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2V77
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Crystal Structure of Human Carboxypeptidase A1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ...
著者Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J.
登録日2007-07-27
公開日2008-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Acta Crystallogr. D Biol. Crystallogr., D64, 2008
6FXU
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BU of 6fxu by Molmil
Crystal structure of human transthyretin mutant T119M at pH 5.5
分子名称: Transthyretin
著者Varejao, N, Esperante, S, Ventura, S, Reverter, D.
登録日2018-03-09
公開日2019-03-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.359 Å)
主引用文献Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FZL
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BU of 6fzl by Molmil
Crystal structure of human transthyretin double mutant K35T/T119M
分子名称: Transthyretin
著者Esperante, S, Ventura, S, Reverter, D, Varejao, N.
登録日2018-03-15
公開日2019-03-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.446 Å)
主引用文献Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
5FW8
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BU of 5fw8 by Molmil
Structure of human transthyretin mutant E89K
分子名称: TRANSTHYRETIN
著者Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2016-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW7
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Structure of human transthyretin mutant A109V
分子名称: TRANSTHYRETIN
著者Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
登録日2016-02-12
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
1ZFI
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BU of 1zfi by Molmil
Solution structure of the leech carboxypeptidase inhibitor
分子名称: Metallocarboxypeptidase inhibitor
著者Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S.
登録日2005-04-20
公開日2005-09-13
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
4D7B
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BU of 4d7b by Molmil
Structure of human transthyretin in complex with Tolcapone
分子名称: TRANSTHYRETIN, Tolcapone
著者Gallego, P, Sant'anna, R.O, Ventura, S, Reverter, D.
登録日2014-11-21
公開日2016-01-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
2BO9
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Human carboxypeptidase A4 in complex with human latexin.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ...
著者Pallares, I, Bonet, R, Garcia-Castellanos, R, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Rueth, F.X.
登録日2005-04-08
公開日2005-04-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
1E6H
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A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
分子名称: SPECTRIN ALPHA CHAIN
著者Vega, M.C, Serrano, L.
登録日2000-08-17
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6G
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BU of 1e6g by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
分子名称: SPECTRIN ALPHA CHAIN, SULFATE ION
著者Vega, M.C, Serrano, L.
登録日2000-08-15
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1H8K
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BU of 1h8k by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
分子名称: SPECTRIN ALPHA CHAIN
著者Vega, M.C, Serrano, L.
登録日2001-02-09
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1PYT
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BU of 1pyt by Molmil
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
分子名称: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
著者Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
登録日1995-06-21
公開日1997-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
2K2X
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BU of 2k2x by Molmil
Solution Structure of Tick Carboxypeptidase Inhibitor at pH 3.5
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Z
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BU of 2k2z by Molmil
Solution structure of the folded domain of intermediate IIIb of Tick Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2Y
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BU of 2k2y by Molmil
Solution structure of the folded domain of intermediate IIIa of Tick Carboxypeptidase Inhibitor
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2KMO
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BU of 2kmo by Molmil
Solution structure of native Leech-derived tryptase inhibitor, LDTI
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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BU of 2kmr by Molmil
Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMP
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Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
分子名称: Leech-derived tryptase inhibitor C
著者Pantoja-Uceda, D, Santoro, J.
登録日2009-08-03
公開日2009-11-10
最終更新日2011-08-10
実験手法SOLUTION NMR
主引用文献Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
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