1O5R
 
 | | Crystal structure of adenosine deaminase complexed with a potent inhibitor | | Descriptor: | 1-[(1R)-3-(6-{[(BENZYLAMINO)CARBONYL]AMINO}-1H-INDOL-1-YL)-1-(HYDROXYMETHYL)PROPYL]-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | | Authors: | Kinoshita, T. | | Deposit date: | 2003-10-05 | | Release date: | 2004-09-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
J.Med.Chem., 47, 2004
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5WVO
 | | Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3 | | Descriptor: | DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ... | | Authors: | Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K. | | Deposit date: | 2016-12-28 | | Release date: | 2017-11-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
Mol. Cell, 68, 2017
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5YJ9
 | | Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ... | | Authors: | Okatsu, K, Sato, Y, Fukai, S. | | Deposit date: | 2017-10-09 | | Release date: | 2018-07-25 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Structural insights into ubiquitin phosphorylation by PINK1.
Sci Rep, 8, 2018
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7X54
 | | A CBg-ParM filament with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ParM/StbA family protein | | Authors: | Koh, A, Ali, S, Robinson, R, Narita, A. | | Deposit date: | 2022-03-04 | | Release date: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | A new actin-like filament from Clostridium botulinum exhibits a new system of filament turn over
To Be Published
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7X59
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7X55
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7X56
 | | A CBg-ParM filament with ADP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ParM/StbA family protein | | Authors: | Koh, A, Ali, S, Robinson, R, Narita, A. | | Deposit date: | 2022-03-04 | | Release date: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | A new actin-like filament from Clostridium botulinum exhibits a new system of filament turn over
To Be Published
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1V5W
 | | Crystal structure of the human Dmc1 protein | | Descriptor: | Meiotic recombination protein DMC1/LIM15 homolog | | Authors: | Kinebuchi, T, Kagawa, W, Enomoto, R, Ikawa, S, Shibata, T, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-11-26 | | Release date: | 2004-05-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein dmc1
Mol.Cell, 14, 2004
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5XPT
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5XPU
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7W4Z
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7W52
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7W51
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7W50
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7YNE
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2ZFU
 | | Structure of the methyltransferase-like domain of nucleomethylin | | Descriptor: | Cerebral protein 1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Minami, H, Hashimoto, H, Murayama, A, Yanagisawa, J, Sato, M, Shimizu, T. | | Deposit date: | 2008-01-14 | | Release date: | 2008-12-02 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Epigenetic control of rDNA loci in response to intracellular energy status
Cell(Cambridge,Mass.), 133, 2008
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2E1W
 | | Crystal structure of adenosine deaminase complexed with potent inhibitors | | Descriptor: | 1-{(1R,2S)-2-HYDROXY-1-[2-(1-NAPHTHYL)ETHYL]PROPYL}-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | | Authors: | Kinoshita, T. | | Deposit date: | 2006-10-30 | | Release date: | 2006-11-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-Based Design and Synthesis of Non-Nucleoside, Potent, and Orally Bioavailable Adenosine Deaminase Inhibitors
J.Med.Chem., 47, 2004
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1QXL
 | | Crystal structure of Adenosine deaminase complexed with FR235380 | | Descriptor: | 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(5-PHENYLPENTANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | | Authors: | Kinoshita, T. | | Deposit date: | 2003-09-08 | | Release date: | 2004-09-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
J.Med.Chem., 47, 2004
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1UML
 | | Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624 | | Descriptor: | 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | | Authors: | Kinoshita, T. | | Deposit date: | 2003-10-03 | | Release date: | 2004-09-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
J.Med.Chem., 47, 2004
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3A33
 | | UbcH5b~Ubiquitin Conjugate | | Descriptor: | GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 | | Authors: | Sakata, E, Satoh, T, Yamamoto, S, Yamaguchi, Y, Yagi-Utsumi, M, Kurimoto, E, Wakatsuki, S, Kato, K. | | Deposit date: | 2009-06-08 | | Release date: | 2009-11-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of UbcH5b~Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2~Ub Conjugates
Structure, 18, 2010
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3ADE
 | | Crystal Structure of Keap1 in Complex with Sequestosome-1/p62 | | Descriptor: | Kelch-like ECH-associated protein 1, SULFATE ION, Sequestosome-1 | | Authors: | Kurokawa, H, Yamamoto, M. | | Deposit date: | 2010-01-19 | | Release date: | 2010-03-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Nat.Cell Biol., 12, 2010
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7Y15
 | | Cryo-EM structure of apo-state MrgD-Gi complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | | Deposit date: | 2022-06-06 | | Release date: | 2022-07-20 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM.
Commun Biol, 5, 2022
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7Y12
 | | Cryo-EM structure of MrgD-Gi complex with beta-alanine | | Descriptor: | BETA-ALANINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | | Deposit date: | 2022-06-06 | | Release date: | 2022-07-20 | | Last modified: | 2023-02-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM.
Commun Biol, 5, 2022
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7Y14
 | | Cryo-EM structure of MrgD-Gi complex with beta-alanine (local) | | Descriptor: | BETA-ALANINE, PALMITIC ACID, Soluble cytochrome b562,Mas-related G-protein coupled receptor member D | | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | | Deposit date: | 2022-06-06 | | Release date: | 2022-07-20 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM.
Commun Biol, 5, 2022
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7Y13
 | | Cryo-EM structure of apo-state MrgD-Gi complex (local) | | Descriptor: | PALMITIC ACID, Soluble cytochrome b562,Mas-related G-protein coupled receptor member D | | Authors: | Suzuki, S, Iida, M, Kawamoto, A, Oshima, A. | | Deposit date: | 2022-06-06 | | Release date: | 2022-07-20 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM.
Commun Biol, 5, 2022
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