7Y12

Cryo-EM structure of MrgD-Gi complex with beta-alanine

Summary for 7Y12

• Entry DOI: 10.2210/pdb7y12/pdb
• EMDB information: 33554
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: gpcr, complex, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 170507.34

Authors

Suzuki, S.,Iida, M.,Kawamoto, A.,Oshima, A. (deposition date: 2022-06-06, release date: 2022-07-20, Last modification date: 2023-02-15)

• Primary citation: Suzuki, S.,Iida, M.,Hiroaki, Y.,Tanaka, K.,Kawamoto, A.,Kato, T.,Oshima, A.; Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM.; Commun Biol, 5:707-707, 2022; PubMed: 35840655; DOI: 10.1038/s42003-022-03668-3

Experimental method

ELECTRON MICROSCOPY (3.1 Å)