2QOJ
 
 | | Coevolution of a homing endonuclease and its host target sequence | | 分子名称: | I-AniI DNA target seq1, I-AniI DNA target seq2, LAGLIDADG endonuclease, ... | | 著者 | Scalley-Kim, M, McConnell Smith, A, Stoddard, B.L. | | 登録日 | 2007-07-20 | | 公開日 | 2008-11-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Coevolution of a homing endonuclease and its host target sequence.
J.Mol.Biol., 372, 2007
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1A73
 | | INTRON-ENCODED ENDONUCLEASE I-PPOI COMPLEXED WITH DNA | | 分子名称: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON 3 (I-PPO) ENCODED ENDONUCLEASE, ... | | 著者 | Flick, K.E, Monnat Junior, R.J, Stoddard, B.L. | | 登録日 | 1998-03-19 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI.
Nature, 394, 1998
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2FLD
 | | I-MsoI Re-Designed for Altered DNA Cleavage Specificity | | 分子名称: | 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | | 著者 | Ashworth, J, Duarte, C.M, Havranek, J.J, Sussman, D, Monnat, R.J, Stoddard, B.L, Baker, D. | | 登録日 | 2006-01-05 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006
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6MAG
 | | native BbvCI B2 dimer in space group C222 | | 分子名称: | ACETATE ION, BbvCI endonuclease subunit 2, GLYCEROL, ... | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2018-08-27 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
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6MAF
 | | native BbvCI A2B2 tetramer at low resolution | | 分子名称: | BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2 | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2018-08-27 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.79 Å) | | 主引用文献 | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
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2O3K
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6M9G
 | | BbvCI B2 dimer with Ta6Br14 clusters | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, BROMIDE ION, ... | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2018-08-23 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
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2O6M
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2OST
 | | The structure of a bacterial homing endonuclease : I-Ssp6803I | | 分子名称: | CALCIUM ION, Putative endonuclease, Synthetic DNA 29 MER | | 著者 | Zhao, L, Bonocora, R.P, Shub, D.A, Stoddard, B.L. | | 登録日 | 2007-02-06 | | 公開日 | 2007-03-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The restriction fold turns to the dark side: a bacterial homing endonuclease with a PD-(D/E)-XK motif.
Embo J., 26, 2007
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5ESP
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1IDE
 | | ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION) | | 分子名称: | ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION, ... | | 著者 | Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L. | | 登録日 | 1995-01-18 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
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6CZI
 | | Structure of a redesigned beta barrel, mFAP1, bound to DFHBI | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP1 | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2018-04-09 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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6UVW
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6UWK
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6UWJ
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6UWH
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6UWG
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6UW0
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6CZH
 | | Structure of a redesigned beta barrel, mFAP0, bound to DFHBI | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP0 | | 著者 | Doyle, L.A, Stoddard, B.L. | | 登録日 | 2018-04-09 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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6D0T
 | | De novo design of a fluorescence-activating beta barrel - BB1 | | 分子名称: | BB1 | | 著者 | Dou, J, Vorobieva, A.A, Sheffler, W, Doyle, L.A, Park, H, Bick, M.J, Mao, B, Foight, G.W, Lee, M, Carter, L, Sankaran, B, Ovchinnikov, S, Marcos, E, Huang, P, Vaughan, J.C, Stoddard, B.L, Baker, D. | | 登録日 | 2018-04-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
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6EG7
 | | BbvCI B2 dimer with I3C clusters | | 分子名称: | 1,2-ETHANEDIOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, BbvCI endonuclease subunit 2, ... | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2018-08-19 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
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4OUD
 | | Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine | | 分子名称: | TYROSINE, Tyrosyl-tRNA synthetase | | 著者 | Takeuchi, R, Mandell, D.J, Lajoie, M.J, Church, G.M, Stoddard, B.L. | | 登録日 | 2014-02-16 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Biocontainment of genetically modified organisms by synthetic protein design.
Nature, 518, 2015
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4QPZ
 | | Crystal structure of the formolase FLS_v2 in space group P 21 | | 分子名称: | Formolase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | | 著者 | Shen, B.W, Siegel, J.B, Stoddard, B.L, Baker, D. | | 登録日 | 2014-06-25 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Computational protein design enables a novel one-carbon assimilation pathway.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4R6J
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1QVJ
 | | structure of NUDT9 complexed with ribose-5-phosphate | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-O-phosphono-beta-D-ribofuranose, ADP-ribose pyrophosphatase, ... | | 著者 | Shen, B.W, Perraud, A.-L, Scharenberg, A.S, Stoddard, B.L. | | 登録日 | 2003-08-27 | | 公開日 | 2003-09-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | The crystal structure and mutational analysis of human NUDT9
J.Mol.Biol., 332, 2003
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