1CK1
 
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1DG9
 | | CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PTPASE COMPLEXED WITH HEPES | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TYROSINE PHOSPHATASE | | 著者 | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | 登録日 | 1999-11-23 | | 公開日 | 1999-12-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of bovine low molecular weight phosphotyrosyl phosphatase complexed with the transition state analog vanadate.
Biochemistry, 36, 1997
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4GZD
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4I56
 | | HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa | | 分子名称: | (3S,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-thioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | 著者 | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Crichelow, C.J, Rodwell, V.W, Wrensford, L.V, Min, J, Burgner II, J.W. | | 登録日 | 2012-11-28 | | 公開日 | 2013-07-17 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
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4I64
 | | 3-hydroxy-3-methylglutaryl Coenzyme A reductase from Pseudomonas mevalonii, a high resolution native structure | | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | 著者 | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | 登録日 | 2012-11-29 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
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4I6W
 | | 3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate | | 分子名称: | (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | 著者 | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | 登録日 | 2012-11-30 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
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4I6A
 | | 3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | 著者 | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | 登録日 | 2012-11-29 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
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4I6Y
 | | 3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate | | 分子名称: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | 著者 | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | 登録日 | 2012-11-30 | | 公開日 | 2013-07-17 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
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1X9E
 | | Crystal structure of HMG-CoA synthase from Enterococcus faecalis | | 分子名称: | HMG-CoA synthase, SULFATE ION | | 著者 | Steussy, C.N, Vartia, A.A, Burgner II, J.W, Sutherlin, A, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 2004-08-20 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA
Biochemistry, 44, 2005
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1YSL
 | | Crystal structure of HMG-CoA synthase from Enterococcus faecalis with AcetoAcetyl-CoA ligand. | | 分子名称: | ACETOACETIC ACID, COENZYME A, GLYCEROL, ... | | 著者 | Steussy, C.N, Vartia, A.A, Burgner II, J.W, Sutherlin, A, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 2005-02-08 | | 公開日 | 2005-11-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA.
Biochemistry, 44, 2005
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1Z12
 | | Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Vanadate | | 分子名称: | Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION | | 著者 | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | 登録日 | 2005-03-03 | | 公開日 | 2005-04-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
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1Z13
 | | Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Molybdate | | 分子名称: | Low molecular weight phosphotyrosine protein phosphatase, MOLYBDATE ION | | 著者 | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | 登録日 | 2005-03-03 | | 公開日 | 2005-04-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
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1P8A
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1QAY
 | | TERNARY COMPLEX OF PSEUDOMONAS MEVALONII HMG-COA REDUCTASE WITH MEVALONATE AND NAD+ | | 分子名称: | (R)-MEVALONATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE) | | 著者 | Tabernero, L, Bochar, D.A, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 1999-04-07 | | 公開日 | 1999-06-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1QAX
 | | TERNARY COMPLEX OF PSEUDOMONAS MEVALONII HMG-COA REDUCTASE WITH HMG-COA AND NAD+ | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE) | | 著者 | Tabernero, L, Bochar, D.A, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 1999-04-06 | | 公開日 | 1999-06-18 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1R7I
 | | HMG-CoA Reductase from P. mevalonii, native structure at 2.2 angstroms resolution. | | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, SULFATE ION | | 著者 | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 2003-10-21 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-COA Reductase.
To be Published
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1R31
 | | HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA | | 分子名称: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, ... | | 著者 | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | | 登録日 | 2003-09-30 | | 公開日 | 2003-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase.
To be Published
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5PNT
 | | CRYSTAL STRUCTURE OF A HUMAN LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE. IMPLICATIONS FOR SUBSTRATE SPECIFICITY | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE | | 著者 | Zhang, M, Stauffacher, C, Lin, D, Vanetten, R. | | 登録日 | 1998-04-29 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity.
J.Biol.Chem., 273, 1998
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1D1Q
 | | CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE SUBSTRATE PNPP | | 分子名称: | 4-NITROPHENYL PHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Wang, S, Tabernero, L, Zhang, M, Harms, E, Van Etten, R.L, Staufacher, C.V. | | 登録日 | 1999-09-20 | | 公開日 | 2000-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Biochemistry, 39, 2000
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7M66
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1T02
 | | Crystal structure of a Statin bound to class II HMG-CoA reductase | | 分子名称: | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | 著者 | Tabernero, L, Rodwell, V.W, Stauffacher, C. | | 登録日 | 2004-04-07 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
J.Biol.Chem., 278, 2003
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1JCK
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1AC6
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