7CKY
 
 | | Cryo-EM structure of PW0464 bound dopamine receptor DRD1-Gs signaling complex | | 分子名称: | 6-[4-[3-[bis(fluoranyl)methoxy]pyridin-2-yl]oxy-2-methyl-phenyl]-1,5-dimethyl-pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Yan, W, Shao, Z. | | 登録日 | 2020-07-20 | | 公開日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184, 2021
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7CKX
 | | Cryo-EM structure of A77636 bound dopamine receptor DRD1-Gs signaling complex | | 分子名称: | (1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Yan, W, Shao, Z. | | 登録日 | 2020-07-20 | | 公開日 | 2021-03-03 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184, 2021
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7SQO
 | | Structure of the orexin-2 receptor(OX2R) bound to TAK-925, Gi and scFv16 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | McGrath, A.P, Kang, Y, Flinspach, M. | | 登録日 | 2021-11-05 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-07-06 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Molecular mechanism of the wake-promoting agent TAK-925.
Nat Commun, 13, 2022
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6KQI
 | | Structure of an allosteric modulator bound to the CB1 cannabinoid receptor | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide, ... | | 著者 | Shao, Z.H, Yan, W. | | 登録日 | 2019-08-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.245 Å) | | 主引用文献 | Structure of an allosteric modulator bound to the CB1 cannabinoid receptor.
Nat.Chem.Biol., 15, 2019
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5U09
 | | High-resolution crystal structure of the human CB1 cannabinoid receptor | | 分子名称: | Cannabinoid receptor 1,GlgA glycogen synthase, DI(HYDROXYETHYL)ETHER, N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide, ... | | 著者 | Shao, Z.H, Yin, J, Rosenbaum, D. | | 登録日 | 2016-11-23 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High-resolution crystal structure of the human CB1 cannabinoid receptor.
Nature, 2016
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