6KQI
Structure of an allosteric modulator bound to the CB1 cannabinoid receptor
Summary for 6KQI
Entry DOI | 10.2210/pdb6kqi/pdb |
Descriptor | Cannabinoid receptor 1,GlgA glycogen synthase,Cannabinoid receptor 1, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide, ... (6 entities in total) |
Functional Keywords | helix, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 58387.24 |
Authors | Shao, Z.H.,Yan, W. (deposition date: 2019-08-17, release date: 2019-10-23, Last modification date: 2023-11-22) |
Primary citation | Shao, Z.,Yan, W.,Chapman, K.,Ramesh, K.,Ferrell, A.J.,Yin, J.,Wang, X.,Xu, Q.,Rosenbaum, D.M. Structure of an allosteric modulator bound to the CB1 cannabinoid receptor. Nat.Chem.Biol., 15:1199-1205, 2019 Cited by PubMed: 31659318DOI: 10.1038/s41589-019-0387-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.245 Å) |
Structure validation
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