4W6W
 
 | | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6 | | Descriptor: | F18 fimbrial adhesin AC, NbFedF6 | | Authors: | Moonens, K, De Kerpel, M, Annelies, C, Cox, E, Pardon, E, Remaut, H, De Greve, H. | | Deposit date: | 2014-08-21 | | Release date: | 2014-12-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
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4W6X
 | | Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF7 | | Descriptor: | F18 fimbrial adhesin AC, Nanobody NbFedF7 | | Authors: | Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H. | | Deposit date: | 2014-08-21 | | Release date: | 2014-12-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
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4G0H
 | | Crystal structure of the N-terminal domain of Helicobacter pylori CagA protein | | Descriptor: | Cytotoxicity-associated immunodominant antigen | | Authors: | Kaplan-Turkoz, B, Remaut, H, Dian, C, Louche, A, Terradot, L. | | Deposit date: | 2012-07-09 | | Release date: | 2012-08-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural insights into Helicobacter pylori oncoprotein CagA interaction with beta 1 integrin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5AFO
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4UV3
 | | Structure of the curli transport lipoprotein CsgG in its membrane- bound conformation | | Descriptor: | CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG | | Authors: | Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. | | Deposit date: | 2014-08-04 | | Release date: | 2014-09-24 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.59 Å) | | Cite: | Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg.
Nature, 516, 2014
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1PG5
 | | CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS | | Descriptor: | Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION | | Authors: | De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J. | | Deposit date: | 2003-05-27 | | Release date: | 2004-06-08 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
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8CN1
 | | hDLG1-PDZ1 in complex with a TAX1 peptide from HTLV-1 | | Descriptor: | Disks large homolog 1, GLU-THR-GLU-VAL, SULFATE ION | | Authors: | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | Deposit date: | 2023-02-21 | | Release date: | 2023-08-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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8CN3
 | | hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1 | | Descriptor: | Disks large homolog 1, GLU-THR-GLU-VAL | | Authors: | Maseko, S, Sogues, A, Volkov, A, Remaut, H, Twizere, J.C. | | Deposit date: | 2023-02-21 | | Release date: | 2023-08-02 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res., 217, 2023
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7YWY
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7OJF
 | | CRYO-EM STRUCTURE OF SLYB13-BAMA FROM ESCHERICHIA COLI | | Descriptor: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | Authors: | Nguyen, V.S, Remaut, H. | | Deposit date: | 2021-05-14 | | Release date: | 2022-07-27 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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4UV2
 | | Structure of the curli transport lipoprotein CsgG in a non-lipidated, pre-pore conformation | | Descriptor: | CURLI PRODUCTION TRANSPORT COMPONENT CSGG | | Authors: | Goyal, P, Krasteva, P.V, Gerven, N.V, Gubellini, F, Broeck, I.V.D, Troupiotis-Tsailaki, A, Jonckheere, W, Pehau-Arnaudet, G, Pinkner, J.S, Chapman, M.R, Hultgren, S.J, Howorka, S, Fronzes, R, Remaut, H. | | Deposit date: | 2014-08-04 | | Release date: | 2014-09-24 | | Last modified: | 2014-12-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and Mechanistic Insights Into the Bacterial Amyloid Secretion Channel Csgg.
Nature, 516, 2014
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4WEN
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V2 | | Descriptor: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC | | Authors: | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | Deposit date: | 2014-09-10 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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4WEM
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1 | | Descriptor: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC, PHOSPHATE ION | | Authors: | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | Deposit date: | 2014-09-10 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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4WEU
 | | Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3 | | Descriptor: | Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD | | Authors: | Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H. | | Deposit date: | 2014-09-11 | | Release date: | 2015-02-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
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8PDZ
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8OPR
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3RFZ
 | | Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate | | Descriptor: | Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... | | Authors: | Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. | | Deposit date: | 2011-04-07 | | Release date: | 2011-06-01 | | Last modified: | 2012-03-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
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6GBH
 | | Helicobacter pylori adhesin HopQ type II bound to the N-terminal domain of human CEACAM1 | | Descriptor: | Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ, SULFATE ION | | Authors: | Moonens, K, Kruse, T, Gerhard, M, Remaut, H. | | Deposit date: | 2018-04-13 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Helicobacter pyloriadhesin HopQ disruptstransdimerization in human CEACAMs.
EMBO J., 37, 2018
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6GBG
 | | Helicobacter pylori adhesin HopQ type I bound to the N-terminal domain of human CEACAM1 | | Descriptor: | BROMIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 1, Outer membrane protein | | Authors: | Moonens, K, Kruse, T, Gerhard, M, Remaut, H. | | Deposit date: | 2018-04-13 | | Release date: | 2018-06-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Helicobacter pyloriadhesin HopQ disruptstransdimerization in human CEACAMs.
EMBO J., 37, 2018
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2W07
 | | Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF | | Descriptor: | CHAPERONE PROTEIN PAPD, MINOR PILIN SUBUNIT PAPF, SULFATE ION | | Authors: | Verger, D, Rose, R.J, Paci, E, Costakes, G, Daviter, T, Hultgren, S, Remaut, H, Ashcroft, A.E, Radford, S.E, Waksman, G. | | Deposit date: | 2008-08-12 | | Release date: | 2008-11-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Determinants of Polymerization Reactivity of the P Pilus Adaptor Subunit Papf.
Structure, 16, 2008
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5NWP
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5ICJ
 | | Crystal structure of the Mycobacterium tuberculosis transcriptional repressor EthR2 in complex with BDM41420 | | Descriptor: | 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)butan-1-one, Probable transcriptional regulatory protein | | Authors: | Wohlkonig, A, Remaut, H, Tanina, A, Meyer, F, Willand, N, Baulard, A.R, Wintjens, R. | | Deposit date: | 2016-02-23 | | Release date: | 2017-04-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Science, 355, 2017
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2J2Z
 | | X-Ray Structure of the Chaperone PapD in complex with the Pilus terminator subunit PapH at 2.3 Angstrom resolution | | Descriptor: | CHAPERONE PROTEIN PAPD, COBALT (II) ION, PAP FIMBRIAL MINOR PILIN PROTEIN, ... | | Authors: | Verger, D, Miller, E, Remaut, H, Waksman, G, Hultgren, S. | | Deposit date: | 2006-08-17 | | Release date: | 2006-11-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular Mechanism of P Pilus Termination in Uropathogenic Escherichia Coli.
Embo Rep., 7, 2006
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5LP2
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3CRE
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