4FHA
 
 | | Structure of Dihydrodipicolinate Synthase from Streptococcus pneumoniae,bound to pyruvate and lysine | | 分子名称: | Dihydrodipicolinate synthase, LYSINE, SODIUM ION | | 著者 | Perugini, M.A, Dogovski, C, Parker, M.W, Gorman, M.A. | | 登録日 | 2012-06-06 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
To be Published
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3TUU
 | | Structure of dihydrodipicolinate synthase from the common grapevine | | 分子名称: | BROMIDE ION, CHLORIDE ION, dihydrodipicolinate synthase | | 著者 | Perugini, M.A, Dobson, R.C, Atkinson, S.C. | | 登録日 | 2011-09-19 | | 公開日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.
Plos One, 7, 2012
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6P90
 | | Crystal structure of PaDHDPS2-H56Q mutant | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL | | 著者 | Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P. | | 登録日 | 2019-06-08 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.
Febs J., 287, 2020
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1PY9
 | | The crystal structure of an autoantigen in multiple sclerosis | | 分子名称: | Myelin-oligodendrocyte glycoprotein, SULFATE ION | | 著者 | Clements, C.S, Reid, H.H, Beddoe, T, Tynan, F.E, Perugini, M.A, Johns, T.G, Bernard, C.C, Rossjohn, J. | | 登録日 | 2003-07-08 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
Proc.Natl.Acad.Sci.USA, 100, 2003
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3HIJ
 | | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | | 著者 | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | | 登録日 | 2009-05-20 | | 公開日 | 2009-11-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
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5KT0
 | | Dihydrodipicolinate reductase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis. | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, MAGNESIUM ION | | 著者 | Christensen, J.B, Soares da Costa, T.P, Faou, P, Pearce, F.G, Panjikar, S, Perugini, M.A. | | 登録日 | 2016-07-10 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Dihydrodipicolinate Reductase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis.
To Be Published
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4XG1
 | | Psychromonas ingrahamii diaminopimelate decarboxylase with LLP | | 分子名称: | (2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid, Diaminopimelate decarboxylase, POTASSIUM ION, ... | | 著者 | Peverelli, M.G, Wubben, J.M, Panjikar, S, Perugini, M.A. | | 登録日 | 2014-12-30 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Expression to crystallization of diaminopimelate decarboxylase from the psychrophile Psychromonas ingrahamii
To Be Published
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4PFM
 | | SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, CITRATE ANION, GLYCEROL, ... | | 著者 | Wubben, J.M, Paxman, J.J, Dogovski, C, Panjikar, S, Perugini, M.A. | | 登録日 | 2014-04-30 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.327 Å) | | 主引用文献 | Defining a Molecular Determinant of Lysine-Mediated Allosteric Inhibition of DHDPS.
To Be Published
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6UE0
 | | Crystal structure of dihydrodipicolinate synthase from Klebsiella pneumoniae bound to pyruvate | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, SULFATE ION | | 著者 | Impey, R.E, Lee, M, Hawkins, D.A, Sutton, J.M, Panjikar, S, Perugini, M.A, Soares da Costa, T.P. | | 登録日 | 2019-09-20 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Mis-annotations of a promising antibiotic target in high-priority gram-negative pathogens.
Febs Lett., 594, 2020
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2OJP
 | | The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL | | 著者 | Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A. | | 登録日 | 2007-01-13 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
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3DEN
 | | Structure of E. coli DHDPS mutant Y107W | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Pearce, F.G, Gerrard, J.A, Perugini, M.A, Jameson, G.B. | | 登録日 | 2008-06-10 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme
Biochemistry, 47, 2008
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3IRD
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2VTY
 | | Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain swapped dimer | | 分子名称: | PROTEIN F1 | | 著者 | Kvansakul, M, Yang, H, Fairlie, W.D, Czabotar, P.E, Fischer, S.F, Perugini, M.A, Huang, D.C.S, Colman, P.M. | | 登録日 | 2008-05-19 | | 公開日 | 2008-06-24 | | 最終更新日 | 2012-01-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Vaccinia Virus Anti-Apoptotic F1L is a Novel Bcl-2-Like Domain-Swapped Dimer that Binds a Highly Selective Subset of Bh3-Containing Death Ligands.
Cell Death Differ., 15, 2008
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2Y6W
 | | Structure of a Bcl-w dimer | | 分子名称: | BCL-2-LIKE PROTEIN 2, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL | | 著者 | Lee, E.F, Evangelista, M, Pettikiriarachchi, A, Dogovski, C, Perugini, M.A, Colman, P.M, Fairlie, W.D. | | 登録日 | 2011-01-27 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of a Bcl-W Domain-Swapped Dimer: Implications for the Function of Bcl-2 Family Proteins.
Structure, 19, 2011
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4JO8
 | | Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor 8, M157 | | 著者 | Berry, R, Ng, N, Saunders, P.M, Vivian, J.P, Lin, J, Deuss, F.A, Corbett, A.J, Forbes, C.A, Widjaja, J.M, Sullivan, L.C, McAlister, A.D, Perugini, M.A, Call, M.J, Scalzo, A.A, Degli-Esposti, M.A, Coudert, J.D, Beddoe, T, Brooks, A.G, Rossjohn, J. | | 登録日 | 2013-03-18 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Targeting of a natural killer cell receptor family by a viral immunoevasin
Nat.Immunol., 14, 2013
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3DAQ
 | | Crystal structure of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus | | 分子名称: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL | | 著者 | Dobson, R.C.J, Burgess, B.R, Jameson, G.B, Gerrard, J.A, Parker, M.W, Perugini, M.A. | | 登録日 | 2008-05-29 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
J.Biol.Chem., 2008
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4HNN
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4I7W
 | | Agrobacterium tumefaciens DHDPS with lysine and pyruvate | | 分子名称: | Dihydrodipicolinate synthase, GLYCEROL, LYSINE | | 著者 | Atkinson, S.C, Dogovski, C, Dobson, R.C.J, Perugini, M.A. | | 登録日 | 2012-12-01 | | 公開日 | 2013-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
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4I7V
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4I7U
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4ICN
 | | Dihydrodipicolinate synthase from shewanella benthica | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DIHYDRODIPICOLINATE SYNTHASE, ... | | 著者 | Wubben, J.M, Paxman, J.J, Dogovski, C, Parker, M.W, Perugini, M.A. | | 登録日 | 2012-12-10 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Cold enzymology offers insight into molecular evolution in quaternary structure
To be Published
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4IK0
 | | Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli | | 分子名称: | Diaminopimelate epimerase, IODIDE ION | | 著者 | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | 登録日 | 2012-12-24 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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4IJZ
 | | Crystal structure of diaminopimelate epimerase from Escherichia coli | | 分子名称: | Diaminopimelate epimerase, NITRATE ION | | 著者 | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | 登録日 | 2012-12-24 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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3VFL
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5KTL
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