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1NF3
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BU of 1nf3 by Molmil
Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Descriptor: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ...
Authors:Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R.
Deposit date:2002-12-12
Release date:2003-03-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
2GBQ
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BU of 2gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, 15 STRUCTURES
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
1SEM
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BU of 1sem by Molmil
STRUCTURAL DETERMINANTS OF PEPTIDE-BINDING ORIENTATION AND OF SEQUENCE SPECIFICITY IN SH3 DOMAINS
Descriptor: 10-RESIDUE PROLINE-RICH PEPTIDE FROM MSOS (ACE-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG), SEM-5
Authors:Lim, W.A, Richards, F.M, Fox, R.O.
Deposit date:1995-03-28
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains.
Nature, 372, 1994
2NSQ
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BU of 2nsq by Molmil
Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-11-06
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
3SO8
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BU of 3so8 by Molmil
Crystal Structure of ANKRA
Descriptor: Ankyrin repeat family A protein 2
Authors:Xu, C, Bochkarev, A, Bian, C.B, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-06-30
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3T04
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BU of 3t04 by Molmil
Crystal structure of monobody 7c12/abl1 sh2 domain complex
Descriptor: GLYCEROL, MONOBODY 7C12, SULFATE ION, ...
Authors:Wojcik, J.B, Wyrzucki, A.M, Koide, S.
Deposit date:2011-07-19
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis.
Cell(Cambridge,Mass.), 147, 2011
3TWQ
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BU of 3twq by Molmil
Crystal structure of ARC4 from human Tankyrase 2 (apo form)
Descriptor: GLYCEROL, SULFATE ION, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWW
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BU of 3tww by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide)
Descriptor: SULFATE ION, Tankyrase-2, human LNPEP
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWS
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BU of 3tws by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWV
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BU of 3twv by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWR
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BU of 3twr by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SH3 domain-binding protein 2, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWX
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BU of 3twx by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWT
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BU of 3twt by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide)
Descriptor: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, NONAETHYLENE GLYCOL, ...
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3TWU
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BU of 3twu by Molmil
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Tankyrase-2
Authors:Guettler, S, Sicheri, F.
Deposit date:2011-09-22
Release date:2011-12-07
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease.
Cell(Cambridge,Mass.), 147, 2011
3UXG
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BU of 3uxg by Molmil
Crystal structure of RFXANK
Descriptor: DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
Authors:Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-05
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V30
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BU of 3v30 by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK
Descriptor: DNA-binding protein RFX5, DNA-binding protein RFXANK
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3UZD
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BU of 3uzd by Molmil
Crystal structure of 14-3-3 GAMMA
Descriptor: 14-3-3 protein gamma, Histone deacetylase 4, MAGNESIUM ION, ...
Authors:Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-07
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2X
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BU of 3v2x by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V31
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BU of 3v31 by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, CHLORIDE ION, Histone deacetylase 4, ...
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2O
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BU of 3v2o by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
Descriptor: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
Authors:Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
2NQ3
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BU of 2nq3 by Molmil
Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
Descriptor: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
1MIL
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BU of 1mil by Molmil
TRANSFORMING PROTEIN
Descriptor: SHC ADAPTOR PROTEIN
Authors:Mikol, V.
Deposit date:1995-09-20
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data.
J.Mol.Biol., 254, 1995
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