1HQC
 
 | | STRUCTURE OF RUVB FROM THERMUS THERMOPHILUS HB8 | | Descriptor: | ADENINE, MAGNESIUM ION, RUVB | | Authors: | Yamada, K, Kunishima, N, Mayanagi, K, Iwasaki, H, Morikawa, K. | | Deposit date: | 2000-12-15 | | Release date: | 2001-02-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of the Holliday junction migration motor protein RuvB from Thermus thermophilus HB8.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1IXS
 | | Structure of RuvB complexed with RuvA domain III | | Descriptor: | Holliday junction DNA helicase ruvA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RuvB | | Authors: | Yamada, K, Miyata, T, Tsuchiya, D, Oyama, T, Fujiwara, Y, Ohnishi, T, Iwasaki, H, Shinagawa, H, Ariyoshi, M, Mayanagi, K, Morikawa, K. | | Deposit date: | 2002-07-04 | | Release date: | 2002-11-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal Structure of the RuvA-RuvB Complex: A Structural Basis for the Holliday Junction Migrating Motor Machinery
Mol.Cell, 10, 2002
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1IXR
 | | RuvA-RuvB complex | | Descriptor: | Holliday junction DNA helicase ruvA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RuvB | | Authors: | Yamada, K, Miyata, T, Tsuchiya, D, Oyama, T, Fujiwara, Y, Ohnishi, T, Iwasaki, H, Shinagawa, H, Ariyoshi, M, Mayanagi, K, Morikawa, K. | | Deposit date: | 2002-07-04 | | Release date: | 2002-11-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of the RuvA-RuvB Complex: A Structural Basis for the Holliday Junction Migrating Motor Machinery
Mol.Cell, 10, 2002
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3AN3
 | | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO3S | | Descriptor: | (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | | Deposit date: | 2010-08-30 | | Release date: | 2011-07-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
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3AN4
 | | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R | | Descriptor: | (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | | Deposit date: | 2010-08-30 | | Release date: | 2011-07-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
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1HJR
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1J23
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain | | Descriptor: | ATP-dependent RNA helicase, putative | | Authors: | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | Deposit date: | 2002-12-25 | | Release date: | 2003-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1J25
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Mn cocrystal | | Descriptor: | ATP-dependent RNA helicase, putative, MANGANESE (II) ION | | Authors: | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | Deposit date: | 2002-12-25 | | Release date: | 2003-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1J24
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Ca cocrystal | | Descriptor: | ATP-dependent RNA helicase, putative, CALCIUM ION | | Authors: | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | Deposit date: | 2002-12-25 | | Release date: | 2003-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1ISR
 | | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion | | Descriptor: | GADOLINIUM ATOM, GLUTAMIC ACID, Metabotropic Glutamate Receptor subtype 1 | | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | | Deposit date: | 2001-12-21 | | Release date: | 2002-03-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1ISS
 | | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist | | Descriptor: | (S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE, Metabotropic Glutamate Receptor subtype 1 | | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | | Deposit date: | 2001-12-21 | | Release date: | 2002-03-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1J22
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, selenomet derivative | | Descriptor: | ATP-dependent RNA helicase, putative | | Authors: | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | Deposit date: | 2002-12-25 | | Release date: | 2003-04-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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1KVE
 | | KILLER TOXIN FROM HALOTOLERANT YEAST | | Descriptor: | SMK TOXIN | | Authors: | Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K. | | Deposit date: | 1996-10-04 | | Release date: | 1997-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin.
Structure, 5, 1997
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1KVD
 | | KILLER TOXIN FROM HALOTOLERANT YEAST | | Descriptor: | SMK TOXIN, SULFATE ION | | Authors: | Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K. | | Deposit date: | 1996-10-04 | | Release date: | 1997-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin.
Structure, 5, 1997
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2D3T
 | | Fatty Acid beta-oxidation multienzyme complex from Pseudomonas Fragi, Form V | | Descriptor: | 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, Fatty oxidation complex alpha subunit, ... | | Authors: | Tsuchiya, D, Shimizu, N, Ishikawa, M, Suzuki, Y, Morikawa, K. | | Deposit date: | 2005-10-01 | | Release date: | 2006-02-21 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Ligand-Induced Domain Rearrangement of Fatty Acid beta-Oxidation Multienzyme Complex
Structure, 14, 2006
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2DHR
 | | Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FtsH | | Authors: | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | | Deposit date: | 2006-03-24 | | Release date: | 2006-06-27 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
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2DI4
 | | Crystal structure of the FtsH protease domain | | Descriptor: | Cell division protein ftsH homolog, MERCURY (II) ION | | Authors: | Suno, R, Niwa, H, Tsuchiya, D, Zhang, X, Yoshida, M, Morikawa, K. | | Deposit date: | 2006-03-28 | | Release date: | 2006-06-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structure of the Whole Cytosolic Region of ATP-Dependent Protease FtsH
Mol.Cell, 22, 2006
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2DSO
 | | Crystal structure of D138N mutant of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus | | Descriptor: | CALCIUM ION, Drp35, GLYCEROL | | Authors: | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | Deposit date: | 2006-07-04 | | Release date: | 2006-12-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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2DG0
 | | Crystal structure of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus | | Descriptor: | DrP35 | | Authors: | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | Deposit date: | 2006-03-07 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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2DG1
 | | Crystal structure of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus, complexed with Ca2+ | | Descriptor: | CALCIUM ION, DrP35, GLYCEROL | | Authors: | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | Deposit date: | 2006-03-07 | | Release date: | 2006-12-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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3VSP
 | | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28 | | Descriptor: | (2R)-2-benzyl-3-[3-({[4-(piperidin-1-yl)benzoyl]amino}methyl)-4-propoxyphenyl]propanoic acid, Peroxisome proliferator-activated receptor gamma | | Authors: | Oyama, T, Waku, T, Ohashi, M, Morikawa, K, Miyachi, H. | | Deposit date: | 2012-04-30 | | Release date: | 2013-05-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28
To be Published
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3W0K
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2DQU
 | | Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | | Descriptor: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | | Authors: | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | | Deposit date: | 2006-05-30 | | Release date: | 2006-06-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
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2DQT
 | | High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | | Descriptor: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | | Authors: | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | | Deposit date: | 2006-05-30 | | Release date: | 2006-06-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
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1HJP
 | | HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI | | Descriptor: | RUVA | | Authors: | Nishino, T, Ariyoshi, M, Iwasaki, H, Shinagawa, H, Morikawa, K. | | Deposit date: | 1997-08-21 | | Release date: | 1998-02-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Functional Analyses of the Domain Structure in the Holliday Junction Binding Protein Ruva
Structure, 6, 1998
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