4Y9E
 
 | | Crystal structure of V30M mutated transthyretin in complex with gamma-mangostin | | Descriptor: | 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, CHLORIDE ION, Transthyretin | | Authors: | Yokoyama, T, Mizuguchi, M. | | Deposit date: | 2015-02-17 | | Release date: | 2015-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor
Sci Rep, 5, 2015
|
|
4Y9C
 | | Crystal structure of V30M mutated transthyretin with bromide in complex with alpha-mangostin | | Descriptor: | 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, BROMIDE ION, Transthyretin | | Authors: | Yokoyama, T, Mizuguchi, M. | | Deposit date: | 2015-02-17 | | Release date: | 2015-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor
Sci Rep, 5, 2015
|
|
4Y9G
 | | Crystal structure of V30M mutated transthyretin in complex with 3-isomangostin | | Descriptor: | 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one, Transthyretin | | Authors: | Yokoyama, T, Mizuguchi, M. | | Deposit date: | 2015-02-17 | | Release date: | 2015-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor
Sci Rep, 5, 2015
|
|
2JX8
 | | Solution structure of hPCIF1 WW domain | | Descriptor: | Phosphorylated CTD-interacting factor 1 | | Authors: | Kouno, T, Iwamoto, Y, Hirose, Y, Aizawa, T, Demura, M, Kawano, K, Ohkuma, Y, Mizuguchi, M. | | Deposit date: | 2007-11-09 | | Release date: | 2008-11-11 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | 1H, 13C, and 15N resonance assignments of hPCIF1 WW domain
To be Published
|
|
1WRU
 | | Structure of central hub elucidated by X-ray analysis of gene product 44; baseplate component of bacteriophage Mu | | Descriptor: | 43 kDa tail protein | | Authors: | Kondou, Y, Kitazawa, D, Takeda, S, Yamashita, E, Mizuguchi, M, Kawano, K, Tsukihara, T. | | Deposit date: | 2004-10-27 | | Release date: | 2005-09-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of central hub elucidated by X-ray analysis of gene product 44; baseplate component of bacteriophage Mu
To be Published
|
|
4N87
 | | Crystal structure of V30M mutant human transthyretin complexed with glabridin | | Descriptor: | 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, Transthyretin | | Authors: | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | Deposit date: | 2013-10-17 | | Release date: | 2014-02-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.794 Å) | | Cite: | Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
|
|
4N85
 | |
4N86
 | | Crystal structure of human transthyretin complexed with glabridin | | Descriptor: | 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, CALCIUM ION, Transthyretin | | Authors: | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | Deposit date: | 2013-10-17 | | Release date: | 2014-02-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Crystal structures of human transthyretin complexed with glabridin
J.Med.Chem., 57, 2014
|
|
2KOZ
 | |
2KP0
 | |
1IRR
 | | Solution structure of paralytic peptide of the silkworm, Bombyx mori | | Descriptor: | paralytic peptide | | Authors: | Miura, K, Kamimura, M, Aizawa, T, Kiuchi, M, Hayakawa, Y, Mizuguchi, M, Kawano, K. | | Deposit date: | 2001-10-23 | | Release date: | 2003-02-11 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of paralytic peptide of silkworm, Bombyx mori
peptides, 23, 2002
|
|
3A5P
 | | Crystal structure of hemagglutinin | | Descriptor: | Haemagglutinin I | | Authors: | Watanabe, N, Sakai, N, Nakamura, T, Nabeshima, Y, Kouno, T, Mizuguchi, M, Kawano, K. | | Deposit date: | 2009-08-10 | | Release date: | 2010-08-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold
J.Mol.Biol., 405, 2011
|
|
6AA4
 | | Crystal structure of MTH1 in complex with alpha-mangostin (cocktail No. 9) | | Descriptor: | 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, ... | | Authors: | Yokoyama, T, Kitakami, R, Mizuguchi, M. | | Deposit date: | 2018-07-17 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
Eur J Med Chem, 167, 2019
|
|
6AA3
 | | Crystal structure of MTH1 in apo form (cocktail No. 1) | | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, ZINC ION | | Authors: | Yokoyama, T, Kitakami, R, Mizuguchi, M. | | Deposit date: | 2018-07-17 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
Eur J Med Chem, 167, 2019
|
|
6AA5
 | | Crystal structure of MTH1 in complex with 3-isomangostin | | Descriptor: | 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, ... | | Authors: | Yokoyama, T, Kitakami, R, Mizuguchi, M. | | Deposit date: | 2018-07-17 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening.
Eur J Med Chem, 167, 2019
|
|
5FVL
 | | Crystal structure of Vps4-Vps20 complex from S.cerevisiae | | Descriptor: | VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 20, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4 | | Authors: | Kojima, R, Obita, T, Onoue, K, Mizuguchi, M. | | Deposit date: | 2016-02-09 | | Release date: | 2016-04-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.973 Å) | | Cite: | Structural Fine-Tuning of Mit Interacting Motif 2 (Mim2) and Allosteric Regulation of Escrt-III by Vps4 in Yeast.
J.Mol.Biol., 428, 2016
|
|
5FVK
 | | Crystal structure of Vps4-Vfa1 complex from S.cerevisiae at 1.66 A resolution. | | Descriptor: | VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4, VPS4-ASSOCIATED PROTEIN 1 | | Authors: | Kojima, R, Obita, T, Onoue, K, Mizuguchi, M. | | Deposit date: | 2016-02-09 | | Release date: | 2016-04-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.658 Å) | | Cite: | Structural Fine-Tuning of Mit Interacting Motif 2 (Mim2) and Allosteric Regulation of Escrt-III by Vps4 in Yeast.
J.Mol.Biol., 428, 2016
|
|
5H0Z
 | | Crystal structure of P113A mutated human transthyretin | | Descriptor: | CHLORIDE ION, SULFATE ION, Transthyretin | | Authors: | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | Deposit date: | 2016-10-07 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.735 Å) | | Cite: | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
5H0V
 | | Crystal structure of H88A mutated human transthyretin | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Transthyretin | | Authors: | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | Deposit date: | 2016-10-07 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
5H0X
 | |
5H0W
 | | Crystal structure of H88F mutated human transthyretin | | Descriptor: | SULFATE ION, Transthyretin | | Authors: | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | Deposit date: | 2016-10-07 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.904 Å) | | Cite: | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
5GPY
 | | Crystal structure of the human TFIIE complex | | Descriptor: | General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, ZINC ION | | Authors: | Obita, T, Miwa, K, Kojima, R, Ohkuma, Y, Tamura, Y, Mizuguchi, M. | | Deposit date: | 2016-08-05 | | Release date: | 2016-11-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of Human General Transcription Factor TFIIE at Atomic Resolution
J.Mol.Biol., 428, 2016
|
|
1V4Z
 | | Solution structure of the N-terminal fragment of S100C/A11 protein | | Descriptor: | Calgizzarin | | Authors: | Kouno, T, Mizuguchi, M, Sakaguchi, M, Makino, E, Huh, N, Kawano, K. | | Deposit date: | 2003-11-20 | | Release date: | 2005-03-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Study on structure-activity relationship between the N-terminal region of S100C protein and its function
Peptide Science, 40, 2003
|
|
1V50
 | | Solution structure of phosphorylated N-terminal fragment of S100C/A11 protein | | Descriptor: | Calgizzarin | | Authors: | Kouno, T, Mizuguchi, M, Sakaguchi, M, Makino, E, Huh, N, Kawano, K. | | Deposit date: | 2003-11-20 | | Release date: | 2005-03-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Study on structure-activity relationship between the N-terminal region of S100C protein and its function
Peptide Science, 40, 2003
|
|
6AAR
 | | Crystal structure of DAPK1 in complex with purpurin | | Descriptor: | Death-associated protein kinase 1, Purpurin | | Authors: | Yokoyama, T, Mizuguchi, M. | | Deposit date: | 2018-07-19 | | Release date: | 2019-07-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural and thermodynamic analyses of interactions between death-associated protein kinase 1 and anthraquinones.
Acta Crystallogr D Struct Biol, 76, 2020
|
|
