4Y9E
Crystal structure of V30M mutated transthyretin in complex with gamma-mangostin
Summary for 4Y9E
| Entry DOI | 10.2210/pdb4y9e/pdb |
| Related | 4PWE 4Y9B 4Y9C 4Y9F 4Y9G |
| Descriptor | Transthyretin, 1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | transthyretin, inhibitor, natural product, transporter, transport protein-inhibitor complex, transport protein/inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 35619.84 |
| Authors | Yokoyama, T.,Mizuguchi, M. (deposition date: 2015-02-17, release date: 2015-09-09, Last modification date: 2023-11-08) |
| Primary citation | Yokoyama, T.,Ueda, M.,Ando, Y.,Mizuguchi, M. Discovery of gamma-Mangostin as an Amyloidogenesis Inhibitor Sci Rep, 5:13570-13570, 2015 Cited by PubMed: 26310724DOI: 10.1038/srep13570 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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