Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042572 | biological_process | retinol metabolic process |
| A | 0070324 | molecular_function | thyroid hormone binding |
| A | 0070327 | biological_process | thyroid hormone transport |
| B | 0042572 | biological_process | retinol metabolic process |
| B | 0070324 | molecular_function | thyroid hormone binding |
| B | 0070327 | biological_process | thyroid hormone transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue MKT A 200 |
| Chain | Residue |
| A | LYS15 |
| A | THR119 |
| A | THR119 |
| A | VAL121 |
| A | CL201 |
| A | CL201 |
| A | CL202 |
| A | HOH301 |
| A | HOH301 |
| A | LYS15 |
| A | LEU17 |
| A | LEU17 |
| A | THR106 |
| A | ALA108 |
| A | ALA108 |
| A | LEU110 |
| A | SER117 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 201 |
| Chain | Residue |
| A | ALA108 |
| A | SER117 |
| A | THR118 |
| A | THR119 |
| A | MKT200 |
| A | MKT200 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 202 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue MKT B 200 |
| Chain | Residue |
| B | LYS15 |
| B | LYS15 |
| B | LEU17 |
| B | LEU17 |
| B | THR106 |
| B | ALA108 |
| B | ALA108 |
| B | LEU110 |
| B | SER117 |
| B | SER117 |
| B | THR119 |
| B | THR119 |
| B | VAL121 |
| B | CL201 |
| B | CL201 |
| B | CL202 |
| B | HOH301 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| B | ALA108 |
| B | SER117 |
| B | THR118 |
| B | THR119 |
| B | MKT200 |
| B | MKT200 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 202 |
| Chain | Residue |
| B | LYS15 |
| B | MKT200 |
Functional Information from PROSITE/UniProt
| site_id | PS00769 |
| Number of Residues | 13 |
| Details | TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS |
| Chain | Residue | Details |
| A | TYR105-SER117 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11418763","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ICT","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Sulfocysteine","evidences":[{"source":"PubMed","id":"17175208","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2H4E","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"4-carboxyglutamate; in a patient with Moyamoya disease","evidences":[{"source":"PubMed","id":"18221012","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02767","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"}]} |
