3DVM
| Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A | Authors: | Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L. | Deposit date: | 2008-07-18 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008
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3DVK
| Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent R-type calcium channel subunit alpha-1E | Authors: | Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L. | Deposit date: | 2008-07-18 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008
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3DVJ
| Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent N-type calcium channel subunit alpha-1B | Authors: | Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L. | Deposit date: | 2008-07-18 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008
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3V0D
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S) | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-07 | Release date: | 2012-05-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0F
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), form II | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-07 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0I
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 256-576, E411F | Descriptor: | SULFATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-08 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0J
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), Deletion of 401-405 | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-08 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0E
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 256-576(C363S) | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-07 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0H
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), complexed with D-MYO-inositol-1,4,5-triphosphate | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-08 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3V0G
| Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), form III | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2011-12-08 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A glutamate switch controls voltage-sensitive phosphatase function. Nat.Struct.Mol.Biol., 19, 2012
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3HFE
| A trimeric form of the Kv7.1 A domain Tail | Descriptor: | Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Xu, Q, Minor, D.L. | Deposit date: | 2009-05-11 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif. Protein Sci., 18, 2009
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3HFC
| A trimeric form of the Kv7.1 A domain Tail, L602M/L606M mutant Semet | Descriptor: | Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Xu, Q, Minor, D.L. | Deposit date: | 2009-05-11 | Release date: | 2009-09-01 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif. Protein Sci., 18, 2009
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3OXQ
| Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex | Descriptor: | CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C | Authors: | Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L. | Deposit date: | 2010-09-21 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29, 2010
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3OX6
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3OX5
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2OVC
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1QDV
| N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 | Descriptor: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 1999-07-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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1QDW
| N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119 | Descriptor: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 1999-07-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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1DSX
| KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT | Descriptor: | PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL) | Authors: | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | Deposit date: | 2000-01-10 | Release date: | 2000-09-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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8D6G
| Nanorana parkeri saxiphilin | Descriptor: | PENTAETHYLENE GLYCOL, Saxiphilin | Authors: | Zakrzewska, S, Chen, Z, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6T
| Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal) | Descriptor: | CACODYLATE ION, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6O
| Nanorana parkeri saxiphilin:F-STX (soaked) | Descriptor: | (2P)-4-({6-[({[(3aS,4R,7R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methoxy}carbonyl)amino]hexyl}carbamoyl)-2-{[4aP,9(9a)P]-6-hydroxy-3-oxo-3H-xanthen-9-yl}benzoic acid, PENTAETHYLENE GLYCOL, Saxiphilin | Authors: | Zakrzewska, S, Chen, Z, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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8D6P
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8D6Q
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8D6S
| Rana catesbeiana saxiphilin mutant - Y558A:STX (co-crystal) | Descriptor: | Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | Deposit date: | 2022-06-06 | Release date: | 2022-11-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family. Proc.Natl.Acad.Sci.USA, 119, 2022
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