3QPC
| Structure of Fusarium Solani Cutinase expressed in Pichia pastoris, crystallized in the presence of Paraoxon | 分子名称: | Cutinase | 著者 | Lu, A, Gosser, Y, Montclare, J.K, Liu, Z, Kong, X. | 登録日 | 2011-02-11 | 公開日 | 2012-02-29 | 実験手法 | X-RAY DIFFRACTION (0.978 Å) | 主引用文献 | Structure of Fusarium Solani Cutinase expressed in Pichia pastoris To be Published
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3R0W
| Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors. | 分子名称: | Multidrug-resistant clinical isolate 769 HIV-1 Protease, N-[(2R)-1-{[(2S,3S)-5-{[(2R)-1-{[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino}-3-chloro-1-oxopropan-2-yl]amino}-3-hydroxy-5-oxo-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide | 著者 | Yedidi, R.S, Gupta, D, Liu, Z, Brunzelle, J, Kovari, I.A, Woster, P.M, Kovari, L.C. | 登録日 | 2011-03-09 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds. Biochem.Biophys.Res.Commun., 421, 2012
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3R0Y
| Crystal Structures of Multidrug-resistant HIV-1 Protease in Complex with Mechanism-Based Aspartyl Protease Inhibitors | 分子名称: | Multidrug-resistant clinical isolate 769 HIV-1 Protease, N-[(2S)-1-{[(2S,3S)-3-hydroxy-5-oxo-5-{[(2R)-1-oxo-3-phenyl-1-(prop-2-yn-1-ylamino)propan-2-yl]amino}-1-phenylpentan-2-yl]amino}-3-methyl-1-oxobutan-2-yl]pyridine-2-carboxamide | 著者 | Yedidi, R.S, Gupta, D, Liu, Z, Brunzelle, J, Kovari, I.A, Woster, P.M, Kovari, L.C. | 登録日 | 2011-03-09 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds. Biochem.Biophys.Res.Commun., 421, 2012
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3SO9
| Darunavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, HIV-1 protease | 著者 | Wang, Y, Liu, Z, Brunzelle, S.J, Kovari, L.C, Kovari, I.A. | 登録日 | 2011-06-30 | 公開日 | 2011-10-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | The higher barrier of darunavir and tipranavir resistance for HIV-1 protease. Biochem.Biophys.Res.Commun., 412, 2011
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3SPK
| Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant | 分子名称: | HIV-1 protease, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE | 著者 | Wang, Y, Liu, Z, Brunzelle, J.S, Kovari, I.A, Kovari, L.C. | 登録日 | 2011-07-01 | 公開日 | 2011-10-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | The higher barrier of darunavir and tipranavir resistance for HIV-1 protease. Biochem.Biophys.Res.Commun., 412, 2011
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5XK5
| Relaxed state of S65-phosphorylated ubiquitin | 分子名称: | Polyubiquitin-B | 著者 | Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | 登録日 | 2017-05-05 | 公開日 | 2017-06-28 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5GUJ
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6IJJ
| Photosystem I of Chlamydomonas reinhardtii | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. | 登録日 | 2018-10-10 | 公開日 | 2019-03-20 | 最終更新日 | 2019-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex. Nat Plants, 5, 2019
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6INW
| A Pericyclic Reaction enzyme | 分子名称: | O-methyltransferase lepI, S-ADENOSYLMETHIONINE | 著者 | Feng, Y, Chang, M, Wang, H, Liu, Z, Zhou, Y. | 登録日 | 2018-10-28 | 公開日 | 2019-07-03 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Crystal structure of the multifunctional SAM-dependent enzyme LepI provides insights into its catalytic mechanism. Biochem.Biophys.Res.Commun., 515, 2019
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6IJO
| Photosystem I of Chlamydomonas reinhardtii | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | 著者 | Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. | 登録日 | 2018-10-10 | 公開日 | 2019-03-20 | 最終更新日 | 2019-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex. Nat Plants, 5, 2019
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6K41
| cryo-EM structure of alpha2BAR-GoA complex | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | 登録日 | 2019-05-23 | 公開日 | 2020-04-15 | 最終更新日 | 2020-05-13 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine. Nat.Chem.Biol., 16, 2020
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6NHY
| Structure of the transmembrane domain of the Death Receptor 5 mutant (G217Y) - Trimer Only | 分子名称: | Tumor necrosis factor receptor superfamily member 10B | 著者 | Chou, J.J, Pan, L, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H, Liu, Z. | 登録日 | 2018-12-24 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling. Cell, 176, 2019
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6JZF
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6JZN
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6K42
| cryo-EM structure of alpha2BAR-Gi1 complex | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | 登録日 | 2019-05-23 | 公開日 | 2020-04-15 | 最終更新日 | 2020-05-13 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine. Nat.Chem.Biol., 16, 2020
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4I3K
| Crystal structure of a metabolic reductase with 1-hydroxy-6-(4-hydroxybenzyl)-4-methylpyridin-2(1H)-one | 分子名称: | 1-hydroxy-6-(4-hydroxybenzyl)-4-methylpyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zheng, B, Yao, Y, Liu, Z, Deng, L, Anglin, J.L, Jiang, H, Prasad, B.V.V, Song, Y. | 登録日 | 2012-11-26 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.3056 Å) | 主引用文献 | Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase. ACS Med Chem Lett, 4, 2013
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4I3L
| Crystal structure of a metabolic reductase with 6-benzyl-1-hydroxy-4-methylpyridin-2(1H)-one | 分子名称: | 6-benzyl-1-hydroxy-4-methylpyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Zheng, B, Yao, Y, Liu, Z, Deng, L, Anglin, J.L, Jiang, H, Prasad, B.V.V, Song, Y. | 登録日 | 2012-11-26 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.292 Å) | 主引用文献 | Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase. ACS Med Chem Lett, 4, 2013
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4IX3
| Crystal structure of a Stt7 homolog from Micromonas algae | 分子名称: | MAGNESIUM ION, MsStt7d protein | 著者 | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | 登録日 | 2013-01-24 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4IX5
| Crystal structure of a Stt7 homolog from Micromonas algae in complex with AMP-PNP | 分子名称: | MAGNESIUM ION, MsStt7d protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | 登録日 | 2013-01-24 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4IX6
| Crystal structure of a Stt7 homolog from Micromonas algae soaked with ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MsStt7d protein | 著者 | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | 登録日 | 2013-01-24 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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4IX4
| Crystal structure of a Stt7 homolog from Micromonas algae in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MsStt7d protein | 著者 | Guo, J, Wei, X, Li, M, Pan, X, Chang, W, Liu, Z. | 登録日 | 2013-01-24 | 公開日 | 2013-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae Protein Cell, 4, 2013
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5YIK
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7KH0
| Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex | 分子名称: | Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C. | 登録日 | 2020-10-19 | 公開日 | 2021-05-26 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex. Cell Res., 31, 2021
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7E2M
| Crystal structure of the RWD domain of human GCN2 - 2 | 分子名称: | eIF-2-alpha kinase GCN2 | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | 登録日 | 2021-02-05 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2. Biochem.Biophys.Res.Commun., 549, 2021
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7E2K
| Crystal structure of the RWD domain of human GCN2 - 1 | 分子名称: | eIF-2-alpha kinase GCN2 | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | 登録日 | 2021-02-05 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.041 Å) | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2. Biochem.Biophys.Res.Commun., 549, 2021
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