7X84
| Cryo-EM structure of the TMEM106B fibril from Parkinson's disease dementia | Descriptor: | Transmembrane protein 106B | Authors: | Zhao, Q.Y, Xia, W.C, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C. | Deposit date: | 2022-03-11 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res., 32, 2022
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7X83
| Cryo-EM structure of the TMEM106B fibril from normal elder | Descriptor: | Transmembrane protein 106B | Authors: | Xia, W.C, Zhao, Q.Y, Fan, Y, Sun, Y.P, Tao, Y.Q, Liu, C. | Deposit date: | 2022-03-11 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res., 32, 2022
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3T4G
| AIIGLMV segment from Alzheimer's Amyloid-Beta displayed on 54-membered macrocycle scaffold | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide (ORN)AIIGLMV(ORN)KF(HAO)(4BF)K | Authors: | Zhao, M, Liu, C, Cheng, P.N, Eisenberg, D, Nowick, J.S. | Deposit date: | 2011-07-26 | Release date: | 2012-10-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Amyloid beta-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity. Nat Chem, 4, 2012
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7V4A
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7V4B
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7V4C
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7V4D
| Heparin-remodelled alpha-synuclein fibrils | Descriptor: | Alpha-synuclein | Authors: | Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2021-08-12 | Release date: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Heparin-remodelled alpha-synuclein fibrils To Be Published
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3VBC
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6L62
| Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | Descriptor: | Capsid protein, Heavy chain of Fab fragment, Light chain of Fab fragment | Authors: | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | Deposit date: | 2019-10-25 | Release date: | 2020-02-12 | Last modified: | 2020-04-29 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope. J.Virol., 94, 2020
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6LM3
| Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | Descriptor: | Capsid protein | Authors: | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | Deposit date: | 2019-12-24 | Release date: | 2020-02-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope. J.Virol., 94, 2020
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4KXB
| Crystal structure of human aminopeptidase A complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX8
| Crystal structure of human aminopeptidase A complexed with amastatin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX7
| Crystal structure of human aminopeptidase A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KXA
| Crystal structure of human aminopeptidase A complexed with aspartate and calcium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX9
| Crystal structure of human aminopeptidase A complexed with arginine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4L3N
| Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | Authors: | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | Deposit date: | 2013-06-06 | Release date: | 2013-07-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus. J.Virol., 87, 2013
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4KXC
| Crystal structure of human aminopeptidase A complexed with glutamate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-25 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KXD
| Crystal structure of human aminopeptidase A complexed with glutamate and calcium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-25 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4MYS
| 1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase with SHCHC and Pyruvate | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, GLYCEROL, ... | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-28 | Release date: | 2014-04-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.423 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
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4MYD
| 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) in complex with SHCHC | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-27 | Release date: | 2014-04-23 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.374 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
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4MXD
| 1.45 angstronm crystal structure of E.coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (MenH) | Descriptor: | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Sun, Y, Yin, S, Feng, Y, Li, J, Zhou, J, Liu, C, Zhu, G, Guo, Z. | Deposit date: | 2013-09-26 | Release date: | 2014-04-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Molecular basis of the general base catalysis of an alpha / beta-hydrolase catalytic triad. J.Biol.Chem., 289, 2014
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4P32
| Crystal structure of E. coli LptB in complex with ADP-magnesium | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION | Authors: | Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D. | Deposit date: | 2014-03-05 | Release date: | 2014-03-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc.Natl.Acad.Sci.USA, 111, 2014
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4P33
| Crystal structure of E. coli LptB-E163Q in complex with ATP-sodium | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Lipopolysaccharide export system ATP-binding protein LptB, ... | Authors: | Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D. | Deposit date: | 2014-03-05 | Release date: | 2014-03-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc.Natl.Acad.Sci.USA, 111, 2014
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4P31
| Crystal structure of a selenomethionine derivative of E. coli LptB in complex with ADP-Magensium | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION | Authors: | Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D. | Deposit date: | 2014-03-05 | Release date: | 2014-03-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc.Natl.Acad.Sci.USA, 111, 2014
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2KKM
| Solution NMR structure of yeast protein YOR252W [residues 38-178]: Northeast Structural Genomics Consortium target YT654 | Descriptor: | Translation machinery-associated protein 16 | Authors: | Cort, J.R, Yee, A, Liu, C, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-26 | Release date: | 2009-10-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of yeast protein YOR252W To be Published
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