6IGB
 
 | | the structure of Pseudomonas aeruginosa Periplasmic gluconolactonase, PpgL | | 分子名称: | ACETATE ION, Periplasmic gluconolactonase, PpgL, ... | | 著者 | Song, Y.J, Shen, Y.L, Wang, K.L, Li, T, Zhu, Y.B, Li, C.C, He, L.H, Zhao, N.L, Zhao, C, Yang, J, Huang, Q, Mu, X.Y. | | 登録日 | 2018-09-25 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structural and Functional Insights into PpgL, a Metal-Independent beta-Propeller Gluconolactonase That Contributes toPseudomonas aeruginosaVirulence.
Infect.Immun., 87, 2019
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2F7X
 | | Protein Kinase A bound to (S)-2-(1H-Indol-3-yl)-1-[5-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine | | 分子名称: | (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE, PKI, inhibitory peptide, ... | | 著者 | Li, Q, Li, T, Zhu, G.D, Gong, J, Claibone, A, Dalton, C, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Bauch, J.L, Marsh, K.C, Bouska, J.J, Arries, S, De Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | | 登録日 | 2005-12-01 | | 公開日 | 2006-06-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 16, 2006
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2F7Z
 | | Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine | | 分子名称: | (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE, PKI, inhibitory peptide, ... | | 著者 | Li, Q, Woods, K.W, Thomas, S, Zhu, G.D, Packard, G, Fisher, J, Li, T, Gong, J, Dinges, J, Song, X, Abrams, J, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Des Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | | 登録日 | 2005-12-01 | | 公開日 | 2006-06-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
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7CPK
 | | Xylanase R from Bacillus sp. TAR-1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Endo-1,4-beta-xylanase A, ... | | 著者 | Kuwata, K, Suzuki, M, Takita, T, Nakatani, K, Li, T, Katano, Y, Kojima, K, Mizutani, K, Mikami, B, Yatsunami, R, Nakamura, S, Yasukawa, K. | | 登録日 | 2020-08-07 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Insight into the mechanism of thermostabilization of GH10 xylanase from Bacillus sp. strain TAR-1 by the mutation of S92 to E.
Biosci.Biotechnol.Biochem., 85, 2021
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7CPL
 | | Xylanase R from Bacillus sp. TAR-1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Endo-1,4-beta-xylanase A, ... | | 著者 | Kuwata, K, Suzuki, M, Takita, T, Nakatani, K, Li, T, Katano, Y, Kojima, K, Mizutani, K, Mikami, B, Yatsunami, R, Nakamura, S, Yasukawa, K. | | 登録日 | 2020-08-07 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Insight into the mechanism of thermostabilization of GH10 xylanase from Bacillus sp. strain TAR-1 by the mutation of S92 to E.
Biosci.Biotechnol.Biochem., 85, 2021
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4ZHU
 | | Crystal structure of a bacterial repressor protein | | 分子名称: | SULFATE ION, YfiR | | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | | 登録日 | 2015-04-27 | | 公開日 | 2016-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.3968 Å) | | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
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4ZHW
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4ZHY
 | | Crystal structure of a bacterial signalling complex | | 分子名称: | FORMIC ACID, SULFATE ION, YfiB, ... | | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | | 登録日 | 2015-04-27 | | 公開日 | 2016-04-27 | | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
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4ZHV
 | | Crystal structure of a bacterial signalling protein | | 分子名称: | SULFATE ION, YfiB | | 著者 | Li, S, Li, T, Wang, Y, Bartlam, M. | | 登録日 | 2015-04-27 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.585 Å) | | 主引用文献 | Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
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1X81
 | | Farnesyl transferase structure of Jansen compound | | 分子名称: | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ... | | 著者 | Li, Q, Claiborne, A, Li, T, Hasvold, L, Stoll, V.S, Muchmore, S, Jakob, C.G, Gu, W, Cohen, J, Hutchins, C, Frost, D, Rosenberg, S.H, Sham, H.L. | | 登録日 | 2004-08-16 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
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6IQW
 | | Cryo-EM structure of Csm effector complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Csm1, Csm2, ... | | 著者 | Huo, Y, Li, T, Wang, N, Dong, Q, Wang, X, Jiang, T. | | 登録日 | 2018-11-09 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Cryo-EM structure of Type III-A CRISPR effector complex.
Cell Res., 28, 2018
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2WSM
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6KM7
 | | The structural basis for the internal interaction in RBBP5 | | 分子名称: | HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, Retinoblastoma-binding protein 5, ... | | 著者 | Han, J, Li, T, Chen, Y. | | 登録日 | 2019-07-31 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
Nucleic Acids Res., 47, 2019
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1RGR
 | | Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability | | 分子名称: | BETA-ALANINE, Presynaptic density protein 95, postsynaptic protein CRIPT peptide | | 著者 | Piserchio, A, Salinas, G.D, Li, T, Marshall, J, Spaller, M.R, Mierke, D.F. | | 登録日 | 2003-11-12 | | 公開日 | 2004-05-18 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide.
Chem.Biol., 11, 2004
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1TWL
 | | Inorganic pyrophosphatase from Pyrococcus furiosus Pfu-264096-001 | | 分子名称: | Inorganic pyrophosphatase | | 著者 | Zhou, W, Tempel, W, Liu, Z.-J, Chen, L, Clancy Kelley, L.-L, Dillard, B.D, Hopkins, R.C, Arendall III, W.B, Rose, J.P, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-07-01 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Inorganic pyrophosphatase from Pyrococcus furiosus Pfu-264096-001
To be published
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6LZ2
 | | Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb44) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | | 著者 | Cai, H, Yao, H, Li, T, Hutter, C, Tang, Y, Li, Y, Seeger, M, Li, D. | | 登録日 | 2020-02-17 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | An improved fluorescent tag and its nanobodies for membrane protein expression, stability assay, and purification.
Commun Biol, 3, 2020
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2HYE
 | | Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex | | 分子名称: | Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... | | 著者 | Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. | | 登録日 | 2006-08-05 | | 公開日 | 2006-10-03 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
Nature, 443, 2006
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1VJK
 | | Putative molybdopterin converting factor, subunit 1 from Pyrococcus furiosus, Pfu-562899-001 | | 分子名称: | molybdopterin converting factor, subunit 1 | | 著者 | Chen, L, Liu, Z.J, Tempel, W, Shah, A, Lee, D, Rose, J.P, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-03-10 | | 公開日 | 2004-08-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Putative molybdopterin converting factor, subunit 1 from Pyrococcus furiosus, Pfu-562899-001 '
To be published
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1XX7
 | | Conserved hypothetical protein from Pyrococcus furiosus Pfu-403030-001 | | 分子名称: | NICKEL (II) ION, UNKNOWN ATOM OR ION, oxetanocin-like protein | | 著者 | Chen, L, Tempel, W, Habel, J, Zhou, W, Nguyen, D, Chang, S.-H, Lee, D, Kelley, L.-L.C, Dillard, B.D, Liu, Z.-J, Bridger, S, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-11-04 | | 公開日 | 2004-12-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | | 主引用文献 | Conserved hypothetical protein from Pyrococcus furiosus Pfu-403030-001
To be published
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1YBZ
 | | Conserved hypothetical protein from Pyrococcus furiosus Pfu-1581948-001 | | 分子名称: | UNKNOWN ATOM OR ION, chorismate mutase | | 著者 | Lee, D, Chen, L, Nguyen, D, Dillard, B.D, Tempel, W, Habel, J, Zhou, W, Chang, S.-H, Kelley, L.-L.C, Liu, Z.-J, Lin, D, Zhang, H, Praissman, J, Bridger, S, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2004-12-21 | | 公開日 | 2005-02-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Conserved hypothetical protein from Pyrococcus furiosus Pfu-1581948-001
To be published
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5WYB
 | | Structure of Pseudomonas aeruginosa DspI | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, Probable enoyl-CoA hydratase/isomerase | | 著者 | Liu, L, Peng, C, Li, T, Li, C, He, L, Song, Y, Zhu, Y, Shen, Y, Bao, R. | | 登録日 | 2017-01-12 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and functional studies on Pseudomonas aeruginosa DspI: implications for its role in DSF biosynthesis.
Sci Rep, 8, 2018
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7DOL
 | | Mycoplasma genitalium RNase R in complex with double-stranded RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | 登録日 | 2020-12-14 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DCY
 | | Apo form of Mycoplasma genitalium RNase R | | 分子名称: | MAGNESIUM ION, Ribonuclease R | | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | 登録日 | 2020-10-27 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DIC
 | | Mycoplasma genitalium RNase R in complex with single-stranded RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | 登録日 | 2020-11-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DID
 | | Mycoplasma genitalium RNase R in complex with ribose methylated single-stranded RNA | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*AP*AP*AP*A)-3'), Ribonuclease R | | 著者 | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | 登録日 | 2020-11-18 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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