7JQO
| Crystal structure of the R64D mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-11 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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7JQN
| Crystal structure of the R64M mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-11 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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7JRX
| Crystal structure of the R64F mutant of Bauhinia Bauhinioides complexed with Bovine Chymotrypsin | Descriptor: | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-13 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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7JOS
| Crystal structure of BbKI complexed with Human Kallikrein 4 | Descriptor: | Kallikrein 4 (Prostase, enamel matrix, prostate), ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-07 | Release date: | 2021-07-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI Acta Crystallogr.,Sect.D, 77, 2021
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7JR2
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7JR1
| Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Bovine Trypsin | Descriptor: | Cationic trypsin, Kunitz-type inihibitor, SODIUM ION, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-11 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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7JQK
| Crystal structure of the R64A mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | Descriptor: | CADMIUM ION, CHLORIDE ION, Kallikrein-4, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-11 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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7JQV
| Crystal structure of the R64F mutant of Bauhinia Bauhinioides Kallikrein Inhibitor complexed with Human Kallikrein 4 | Descriptor: | CHLORIDE ION, Kallikrein 4 (Prostase, enamel matrix, ... | Authors: | Li, M, Wlodawer, A, Gustchina, A. | Deposit date: | 2020-08-11 | Release date: | 2021-07-21 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021
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8J0N
| cryo-EM structure of human EMC | Descriptor: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | Authors: | Li, M, Zhang, C, Wu, J, Lei, M. | Deposit date: | 2023-04-11 | Release date: | 2024-04-03 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
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8J0O
| cryo-EM structure of human EMC and VDAC | Descriptor: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | Authors: | Li, M, Zhang, C, Wu, J, Lei, M. | Deposit date: | 2023-04-11 | Release date: | 2024-04-03 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
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2QOP
| Crystal structure of the transcriptional regulator AcrR from Escherichia coli | Descriptor: | HTH-type transcriptional regulator acrR | Authors: | Li, M, Gu, R, Su, C.-C, McDermott, G, Yu, E.W. | Deposit date: | 2007-07-20 | Release date: | 2008-02-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of the transcriptional regulator AcrR from Escherichia coli. J.Mol.Biol., 374, 2007
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1DPJ
| THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEINASE A, PROTEINASE INHIBITOR IA3 PEPTIDE, ... | Authors: | Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. | Deposit date: | 1999-12-27 | Release date: | 2000-05-03 | Last modified: | 2021-07-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
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1DP5
| THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT INHIBITOR | Descriptor: | PROTEINASE A, PROTEINASE INHIBITOR IA3, beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. | Deposit date: | 1999-12-23 | Release date: | 2000-05-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
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5C9B
| Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii | Descriptor: | ApRick protease | Authors: | Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A. | Deposit date: | 2015-06-26 | Release date: | 2015-10-14 | Last modified: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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5C9D
| Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii | Descriptor: | ApRick protease, SODIUM ION | Authors: | Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A. | Deposit date: | 2015-06-26 | Release date: | 2015-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease Acta Crystallogr.,Sect.D, 71, 2015
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5E0S
| crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | Descriptor: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | Authors: | LI, M, Wlodawer, A, Maurizi, M. | Deposit date: | 2015-09-29 | Release date: | 2016-02-17 | Last modified: | 2016-04-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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5DZK
| Crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | Descriptor: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, BEZ-LEU-LEU | Authors: | LI, M, Wlodawer, A, Maurizi, M. | Deposit date: | 2015-09-25 | Release date: | 2016-02-17 | Last modified: | 2016-04-13 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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5FIV
| STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR | Descriptor: | RETROPEPSIN, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | Authors: | Li, M, Lee, T, Morris, G, Laco, G, Wong, C, Olson, A, Elder, J, Wlodawer, A, Gustchina, A. | Deposit date: | 1998-12-02 | Release date: | 1998-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease Proteins, 38, 2000
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6U8Q
| CryoEM structure of HIV-1 cleaved synaptic complex (CSC) intasome | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | Authors: | Li, M, Chen, X, Craigie, R. | Deposit date: | 2019-09-05 | Release date: | 2020-02-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.67 Å) | Cite: | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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6VDK
| CryoEM structure of HIV-1 conserved Intasome Core | Descriptor: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | Authors: | Li, M, Chen, X, Craigie, R. | Deposit date: | 2019-12-27 | Release date: | 2020-02-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies. J.Mol.Biol., 432, 2020
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5TBF
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2B7F
| Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design | Descriptor: | (ACE)APQV(STA)VMHP peptide, HTLV protease, PHOSPHATE ION | Authors: | Li, M, Laco, G.S, Jaskolski, M, Rozycki, J, Alexandratos, J, Wlodawer, A, Gustchina, A. | Deposit date: | 2005-10-04 | Release date: | 2005-12-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design Proc.Natl.Acad.Sci.Usa, 102, 2005
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8IP4
| Cryo-EM structure of hMRS-highEDTA | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | Deposit date: | 2023-03-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP5
| Cryo-EM structure of hMRS2-lowEDTA | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | Deposit date: | 2023-03-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP6
| Cryo-EM structure of hMRS2-rest | Descriptor: | CHLORIDE ION, Magnesium transporter MRS2 homolog, mitochondrial | Authors: | Li, M, Li, Y, Yang, X, Shen, Y.Q. | Deposit date: | 2023-03-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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