6YXJ
 
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5HOL
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5HIH
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4WUR
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5LC0
 | | Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor | | 分子名称: | N-((S)-3-(4-(aminomethyl)phenyl)-1-(((R)-4-guanidino-1-(5-hydroxy-1,3,2-dioxaborinan-2-yl)butyl)amino)-1-oxopropan-2-yl)benzamide, NS2B-NS3 protease,NS2B-NS3 protease | | 著者 | Lei, J, Hansen, G, Zhang, L.L, Hilgenfeld, R. | | 登録日 | 2016-06-18 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor.
Science, 353, 2016
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3BJV
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3CZC
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4P16
 | | Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus | | 分子名称: | ORF1a, ZINC ION | | 著者 | Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R. | | 登録日 | 2014-02-25 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features.
Antiviral Res., 109C, 2014
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3L8R
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3RK6
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5NGN
 | | Lybatide 2, a cystine-rich peptide from Lycium barbarum | | 分子名称: | ACETONITRILE, GLYCEROL, TETRAETHYLENE GLYCOL, ... | | 著者 | Lei, J, Tan, W.L, Sakai, N, Hilgenfeld, R. | | 登録日 | 2017-03-18 | | 公開日 | 2017-07-26 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold.
Sci Rep, 7, 2017
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3D3F
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3F7J
 | | B.subtilis YvgN | | 分子名称: | NITRATE ION, POTASSIUM ION, YvgN protein | | 著者 | Zhou, Y.F, Lei, J, Liang, Y.H, Su, X.-D. | | 登録日 | 2008-11-09 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis
Protein Sci., 18, 2009
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1BAI
 | | Crystal structure of Rous sarcoma virus protease in complex with inhibitor | | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE | | 著者 | Wu, J, Adomat, J.M, Ridky, T.W, Louis, J.M, Leis, J, Harrison, R.W, Weber, I.T. | | 登録日 | 1998-04-17 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
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4V6K
 | | Structural insights into cognate vs. near-cognate discrimination during decoding. | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | | 登録日 | 2011-01-07 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (8.25 Å) | | 主引用文献 | Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
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4V6L
 | | Structural insights into cognate vs. near-cognate discrimination during decoding. | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | | 登録日 | 2011-01-07 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (13.2 Å) | | 主引用文献 | Structural insights into cognate versus near-cognate discrimination during decoding.
Embo J., 30, 2011
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1A94
 | | STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES | | 分子名称: | N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE | | 著者 | Wu, J, Adomat, J.M, Ridky, T.W, Louis, J.M, Leis, J, Harrison, R.W, Weber, I.T. | | 登録日 | 1998-04-16 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for specificity of retroviral proteases.
Biochemistry, 37, 1998
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4WTR
 | | Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaribiose | | 分子名称: | beta-1,3-glucanosyltransferase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | 著者 | Qin, Z, Yan, Q, Lei, J, Yang, S, Jiang, Z. | | 登録日 | 2014-10-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | The first crystal structure of a glycoside hydrolase family 17 beta-1,3-glucanosyltransferase displays a unique catalytic cleft.
Acta Crystallogr.,Sect.D, 71, 2015
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4WTP
 | | Crystal structure of glycoside hydrolase family 17 beta-1,3-glucanosyltransferase from Rhizomucor miehei | | 分子名称: | 1,2-ETHANEDIOL, beta-1,3-glucanosyltransferase | | 著者 | Qin, Z, Yan, Q, Lei, J, Yang, S, Jiang, Z. | | 登録日 | 2014-10-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The first crystal structure of a glycoside hydrolase family 17 beta-1,3-glucanosyltransferase displays a unique catalytic cleft.
Acta Crystallogr.,Sect.D, 71, 2015
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4WTS
 | | Active-site mutant of Rhizomucor miehei beta-1,3-glucanosyltransferase in complex with laminaritriose | | 分子名称: | beta-1,3-glucanosyltransferase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | 著者 | Qin, Z, Yan, Q, Lei, J, Yang, S, Jiang, Z. | | 登録日 | 2014-10-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The first crystal structure of a glycoside hydrolase family 17 beta-1,3-glucanosyltransferase displays a unique catalytic cleft.
Acta Crystallogr.,Sect.D, 71, 2015
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4CSU
 | | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | | 分子名称: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ... | | 著者 | Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N. | | 登録日 | 2014-03-10 | | 公開日 | 2014-06-04 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
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2YKR
 | | 30S ribosomal subunit with RsgA bound in the presence of GMPPNP | | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N. | | 登録日 | 2011-05-30 | | 公開日 | 2011-08-24 | | 最終更新日 | 2017-08-30 | | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | | 主引用文献 | Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7OXJ
 | | ttSlyD with M8A pseudo-wild-type S2 peptide | | 分子名称: | 30S ribosomal protein S2, CHLORIDE ION, Fragment of 30S ribosomal protein S2 peptide, ... | | 著者 | Pazicky, S, Lei, J, Loew, C. | | 登録日 | 2021-06-22 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
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7OXK
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7OXH
 | | ttSlyD with pseudo-wild-type S2 peptide | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 30S ribosomal protein S2, CHLORIDE ION, ... | | 著者 | Pazicky, S, Lei, J, Loew, C. | | 登録日 | 2021-06-22 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
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