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4GT7
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BU of 4gt7 by Molmil
An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation
Descriptor: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wurzburg, B.A, Kim, B.K, Jardetzky, T.S.
Deposit date:2012-08-28
Release date:2012-09-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.
J.Biol.Chem., 287, 2012
4JF7
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BU of 4jf7 by Molmil
Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Welch, B.D, Yuan, P, Bose, S, Kors, C.A, Lamb, R.A, Jardetzky, T.S.
Deposit date:2013-02-27
Release date:2013-09-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5018 Å)
Cite:Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain.
Plos Pathog., 9, 2013
7SHT
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BU of 7sht by Molmil
Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
Authors:Pennington, L.F, Jardetzky, T.S.
Deposit date:2021-10-11
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (7.29 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
1F2Q
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BU of 1f2q by Molmil
CRYSTAL STRUCTURE OF THE HUMAN HIGH-AFFINITY IGE RECEPTOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Garman, S.C, Kinet, J.P, Jardetzky, T.S.
Deposit date:2000-05-28
Release date:2000-06-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the human high-affinity IgE receptor.
Cell(Cambridge,Mass.), 95, 1998
1F6A
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BU of 1f6a by Molmil
Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Wurzburg, B.A, Tarchevskaya, S.S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2000-06-20
Release date:2000-07-20
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc (epsilon) RI (alpha).
Nature, 406, 2000
1FP5
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BU of 1fp5 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN IGE-FC CEPSILON3-CEPSILON4 FRAGMENT.
Descriptor: IGE HEAVY CHAIN EPSILON-1
Authors:Wurzburg, B.A, Garman, S.C, Jardetzky, T.S.
Deposit date:2000-08-30
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains.
Immunity, 13, 2000
1NYU
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BU of 1nyu by Molmil
Crystal Structure of Activin A Bound to the ECD of ActRIIB
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1NYS
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BU of 1nys by Molmil
Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Descriptor: Inhibin beta A chain, activin receptor
Authors:Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2003-02-13
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1J87
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BU of 1j87 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), HEXAGONAL CRYSTAL FORM 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J89
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BU of 1j89 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J86
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BU of 1j86 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), MONOCLINIC CRYSTAL FORM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1J88
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BU of 1j88 by Molmil
HUMAN HIGH AFFINITY FC RECEPTOR FC(EPSILON)RI(ALPHA), TETRAGONAL CRYSTAL FORM 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR ALPHA-SUBUNIT, ...
Authors:Garman, S.C, Sechi, S, Kinet, J.P, Jardetzky, T.S.
Deposit date:2001-05-20
Release date:2001-08-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms.
J.Mol.Biol., 311, 2001
1KG0
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BU of 1kg0 by Molmil
Structure of the Epstein-Barr Virus gp42 Protein Bound to the MHC class II Receptor HLA-DR1
Descriptor: Hemagglutinin HA Peptide, MHC class II Receptor HLA-DR1, gp42 Protein
Authors:Mullen, M.M, Haan, K.M, Longnecker, R, Jardetzky, T.S.
Deposit date:2001-11-25
Release date:2002-03-27
Last modified:2016-11-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1.
Mol.Cell, 9, 2002
1SVF
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BU of 1svf by Molmil
PARAMYXOVIRUS SV5 FUSION PROTEIN CORE
Descriptor: CHLORIDE ION, PROTEIN (FUSION GLYCOPROTEIN)
Authors:Baker, K.A, Dutch, R.E, Lamb, R.A, Jardetzky, T.S.
Deposit date:1999-02-27
Release date:1999-03-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for paramyxovirus-mediated membrane fusion.
Mol.Cell, 3, 1999
1Z4V
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BU of 1z4v by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH 7.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4X
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BU of 1z4x by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Z
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BU of 1z4z by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA(soaked with sialic acid, pH7.0))
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4W
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BU of 1z4w by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z50
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BU of 1z50 by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0)
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Y
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BU of 1z4y by Molmil
Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-03-16
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1ZTM
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BU of 1ztm by Molmil
Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein
Authors:Yin, H.S, Paterson, R.G, Wen, X, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-05-27
Release date:2005-07-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein
Proc.Natl.Acad.Sci.USA, 102, 2005
2B0U
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BU of 2b0u by Molmil
The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
2B9B
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BU of 2b9b by Molmil
Structure of the Parainfluenza Virus 5 F Protein in its Metastable, Pre-fusion Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Yin, H.-S, Wen, X, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2005-10-11
Release date:2006-01-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation
Nature, 439, 2006
1BXT
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BU of 1bxt by Molmil
STREPTOCOCCAL SUPERANTIGEN (SSA) FROM STREPTOCOCCUS PYOGENES
Descriptor: PROTEIN (STREPTOCOCCAL SUPERANTIGEN)
Authors:Sundberg, E, Jardetzky, T.
Deposit date:1998-10-08
Release date:1998-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for HLA-DQ binding by the streptococcal superantigen SSA.
Nat.Struct.Biol., 6, 1999
3FD4
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BU of 3fd4 by Molmil
Crystal Structure of Epstein-Barr virus gp42 protein
Descriptor: Glycoprotein gp42
Authors:Kirschner, A, Jardetzky, T.
Deposit date:2008-11-24
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry.
Structure, 17, 2009

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