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Structure of Type VI secretion system cargo delivery vehicle Hcp-VgrG-PAAR
Descriptor:	Bacterodales T6SS protein TssD (Hcp), Type VI secretion system spike protein Paar, Type VI secretion system spike protein VgrG
Authors:	Wen, Y, He, W, Zhu, L.
Deposit date:	2022-09-01
Release date:	2023-07-12
Last modified:	2023-08-30
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Structure and assembly of type VI secretion system cargo delivery vehicle. Cell Rep, 42, 2023

6MQC

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-c.01 in complex with FP (residue 512-519)
Descriptor:	0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-09
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (1.99 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQM

Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV Env fusion peptide residue 512-519, antibody Fab heavy chain, antibody Fab light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (3.484 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQR

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519)
Descriptor:	CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ...
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6N16

Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-b.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV fusion peptide (512-519), antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-11-08
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.302 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQE

Vaccine-elicited NHP FP-targeting HIV neutralizing antibody DFPH-a.15 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	DFPHa.15 antibody Fab heavy chain, DFPHa.15 antibody Fab light chain, HIV fusion peptide
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-09
Release date:	2019-07-31
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.459 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MQS

Vaccine-elicited NHP FP-targeting HIV neutralizing antibody A12V163-a.01 in complex with HIV fusion peptide (residue 512-519)
Descriptor:	HIV fusion peptide residue 512-519, antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain
Authors:	Xu, K, Wang, Y, Kwong, P.D.
Deposit date:	2018-10-10
Release date:	2019-07-31
Last modified:	2019-11-13
Method:	X-RAY DIFFRACTION (2.997 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

3KPH

Crystal structure of Mycoplasma arthritidis-derived mitogen
Descriptor:	PHOSPHATE ION, Superantigen
Authors:	Liu, L.H, Li, H.M.
Deposit date:	2009-11-16
Release date:	2010-05-12
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Crystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped Dimer. J.Mol.Biol., 399, 2010

6L42

Structure of severe fever with thrombocytopenia syndrome virus L protein
Descriptor:	MAGNESIUM ION, RNA polymerase
Authors:	Wang, P, Lou, Z.
Deposit date:	2019-10-15
Release date:	2020-05-13
Last modified:	2021-12-01
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation. Nat Microbiol, 5, 2020

3EOB

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form II
Descriptor:	Efalizumab Fab fragment, heavy chain, light chain, ...
Authors:	Li, S, Ding, J.
Deposit date:	2008-09-26
Release date:	2009-04-14
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (3.6 Å)
Cite:	Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009

3EOA

Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I
Descriptor:	Efalizumab Fab fragment, heavy chain, light chain, ...
Authors:	Li, S, Ding, J.
Deposit date:	2008-09-26
Release date:	2009-04-14
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009

3EO9

Crystal structure the Fab fragment of Efalizumab
Descriptor:	Efalizumab Fab fragment, heavy chain, light chain
Authors:	Li, S, Ding, J.
Deposit date:	2008-09-26
Release date:	2009-04-14
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Proc.Natl.Acad.Sci.USA, 106, 2009

6M18

ACE2-B0AT1 complex
Descriptor:	1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Zhou, Q.
Deposit date:	2020-02-25
Release date:	2020-03-11
Last modified:	2020-11-04
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367, 2020

6M1D

ACE2-B0AT1 complex, open conformation
Descriptor:	Angiotensin-converting enzyme 2, Sodium-dependent neutral amino acid transporter B(0)AT1
Authors:	Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Zhou, Q.
Deposit date:	2020-02-25
Release date:	2020-03-11
Last modified:	2020-04-08
Method:	ELECTRON MICROSCOPY (4.5 Å)
Cite:	Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367, 2020

6MPH

Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ...
Authors:	Acharya, P, Xu, K, Kwong, P.D.
Deposit date:	2018-10-06
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.8 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

3GIZ

Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab
Descriptor:	Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, light chain, ...
Authors:	Du, J, Yang, H, Ding, J.
Deposit date:	2009-03-07
Release date:	2009-05-26
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20 Mol.Immunol., 46, 2009

6N1W

Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DFPH-a.15 Light chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-11-12
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6N1V

Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-a.01 Heavy chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-11-12
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (4 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6MPG

Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ...
Authors:	Acharya, P, Kwong, P.D.
Deposit date:	2018-10-06
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6NF2

Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor:	0PV-c.01 Heavy Chain, 0PV-c.01 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2018-12-18
Release date:	2019-07-24
Last modified:	2020-07-29
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019

6NZ7

Crystal structure of broadly neutralizing Influenza A antibody 429 B01 in complex with Hemagglutinin Hong Kong 1968
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 429 B01 FAB heavy chain, 429 B01 FAB light chain, ...
Authors:	Zhou, T, Kwong, P.D.
Deposit date:	2019-02-13
Release date:	2019-05-08
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine. Sci Immunol, 4, 2019

7C2L

S protein of SARS-CoV-2 in complex bound with 4A8
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Yan, R.H, Zhang, Y.Y, Guo, Y.Y, Li, Y.N, Xia, L, Zhou, Q.
Deposit date:	2020-05-08
Release date:	2020-07-01
Last modified:	2021-02-17
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2. Science, 369, 2020

4DG2

Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20
Descriptor:	MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:	Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:	2012-01-24
Release date:	2012-06-06
Last modified:	2013-01-02
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012

4DG0

Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
Descriptor:	MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:	Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:	2012-01-24
Release date:	2012-06-06
Last modified:	2013-01-02
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012

4DFZ

Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20
Descriptor:	MYRISTIC ACID, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:	Bastidas, A.C, Steichen, J.M, Taylor, S.S.
Deposit date:	2012-01-24
Release date:	2012-06-06
Last modified:	2013-01-02
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. J.Mol.Biol., 422, 2012

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