6SWS
 
 | | The DBB dimerization domain of B-cell adaptor for PI3K (BCAP) is required for down regulation of inflammatory signalling through the Toll-like receptor pathway | | 分子名称: | Phosphoinositide 3-kinase adapter protein 1 | | 著者 | Lauenstein, J.U, Scherm, M.J, Udgata, A, Moncrieffe, M.C, Fisher, D, Gay, N.J. | | 登録日 | 2019-09-23 | | 公開日 | 2020-02-19 | | 最終更新日 | 2020-04-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain.
J Immunol., 204, 2020
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6I3N
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4ARN
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1MD6
 | | High resolution crystal structure of murine IL-1F5 reveals unique loop conformation for specificity | | 分子名称: | interleukin 1 family, member 5 (delta) | | 著者 | Pei, X.Y, Dunn, E.F, Gay, N.J, O'Neill, L.A. | | 登録日 | 2002-08-07 | | 公開日 | 2003-09-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-Resolution Structure of Murine Interleukin 1 Homologue IL-1F5 Reveals Unique Loop Conformations for Receptor Binding Specificity.
Biochemistry, 42, 2003
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1YGO
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4ARR
 | | Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, TOLL RECEPTOR, ... | | 著者 | Gangloff, M, Gay, N.J. | | 登録日 | 2012-04-26 | | 公開日 | 2013-02-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Liesegang-Like Patterns of Toll Crystals Grown in Gel.
J.Appl.Crystallogr., 46, 2013
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4BV4
 | | Structure and allostery in Toll-Spatzle recognition | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN SPAETZLE C-106, PROTEIN TOLL, ... | | 著者 | Lewis, M.F, Arnot, C.J, Beeston, H, McCoy, A, Ashcroft, A.E, Gay, N.J, Gangloff, M. | | 登録日 | 2013-06-24 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Cytokine Spatzle Binds to the Drosophila Immunoreceptor Toll with a Neurotrophin-Like Specificity and Couples Receptor Activation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2YJN
 | | Structure of the glycosyltransferase EryCIII from the erythromycin biosynthetic pathway, in complex with its activating partner, EryCII | | 分子名称: | DTDP-4-KETO-6-DEOXY-HEXOSE 3,4-ISOMERASE, GLYCOSYLTRANSFERASE | | 著者 | Moncrieffe, M.C, Fernandez, M.J, Spiteller, D, Matsumura, H, Gay, N.J, Luisi, B.F, Leadlay, P.F. | | 登録日 | 2011-05-20 | | 公開日 | 2011-11-09 | | 最終更新日 | 2015-04-01 | | 実験手法 | X-RAY DIFFRACTION (3.091 Å) | | 主引用文献 | Structure of the Glycosyltransferase Eryciii in Complex with its Activating P450 Homologue Erycii.
J.Mol.Biol., 415, 2012
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5FOR
 | | Cryptic TIR | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, PENTAETHYLENE GLYCOL, PHOSPHOINOSITIDE 3-KINASE ADAPTER PROTEIN 1 | | 著者 | Halabi, S, Gay, N.J, Moncrieffe, M.C. | | 登録日 | 2015-11-25 | | 公開日 | 2016-12-07 | | 最終更新日 | 2017-03-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome.
J. Biol. Chem., 292, 2017
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7B1B
 | | Cryo-EM of Aedes Aegypti Toll5A dimer bound to Spz1C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AAEL013433-PA, ... | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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7B1C
 | | Cryo-EM of Aedes Aegypti Toll5A trimer bound to Spz1C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AAEL013433-PA, ... | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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7B1D
 | | Cryo-EM of Aedes Aegypti Toll5A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor | | 著者 | Gangloff, M, Hardwick, S.W, Chirgadze, D.Y. | | 登録日 | 2020-11-24 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti.
Nat Commun, 13, 2022
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2Y92
 | | Crystal structure of MAL adaptor protein | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | | 著者 | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | | 登録日 | 2011-02-11 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection.
Proc.Natl.Acad.Sci.USA, 108, 2011
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