8H98
 
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 1 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
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8H9C
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 4 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
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8H9B
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 3 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
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8HK0
 | | Crystal structure of Fic32-33 complex from Streptomyces ficellus NRRL 8067 | | 分子名称: | Acyl-CoA dehydrogenase, Dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cheng, Y, Qiao, H, Liu, W, Fang, P. | | 登録日 | 2022-11-24 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Oxidase Heterotetramer Completes 1-Azabicyclo[3.1.0]hexane Formation with the Association of a Nonribosomal Peptide Synthetase.
J.Am.Chem.Soc., 145, 2023
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2JZY
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7E2M
 | | Crystal structure of the RWD domain of human GCN2 - 2 | | 分子名称: | eIF-2-alpha kinase GCN2 | | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-02-05 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
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7E2K
 | | Crystal structure of the RWD domain of human GCN2 - 1 | | 分子名称: | eIF-2-alpha kinase GCN2 | | 著者 | Hei, Z, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-02-05 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.041 Å) | | 主引用文献 | Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
Biochem.Biophys.Res.Commun., 549, 2021
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7EA9
 | | Crystal Structure of human lysyl-tRNA synthetase Y145H mutant | | 分子名称: | 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, Lysine--tRNA ligase | | 著者 | Wu, S, Hei, Z, Zheng, L, Zhou, J, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2021-03-06 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Biochem.Biophys.Res.Commun., 554, 2021
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7X3O
 | | Crystal structure of Aldo-keto reductase 1C3 complexed with compound S07054 | | 分子名称: | (2~{R})-2-(3-fluoranyl-4-pyrimidin-5-yl-phenyl)butanoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Jiang, J, Liu, Y, He, S, Chen, Y, Chu, X, Liu, Y, Guo, Q, Zhao, L, Feng, F, Liu, W, Zhang, X, Fang, P, Sun, H. | | 登録日 | 2022-03-01 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Crystal structure of Aldo-keto reductase 1C3 complexed with compound S07054
To Be Published
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3N9T
 | | Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4 | | 分子名称: | 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, CITRATE ANION, FE (III) ION, ... | | 著者 | Liu, W, Shen, W, Fang, P, Li, J, Cui, Z. | | 登録日 | 2010-05-31 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cryatal structure of Hydroxyquinol 1,2-dioxygenase from Pseudomonas putida DLL-E4
To be Published
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2MLK
 | | Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae | | 分子名称: | RstA | | 著者 | Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T. | | 登録日 | 2014-03-02 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
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6ZWJ
 | | Neisseria gonorrhoeae transaldolase at 1.35 Angstrom resolution | | 分子名称: | CITRIC ACID, GLYCEROL, Transaldolase | | 著者 | Rabe von Pappenheim, F, Wensien, M, Sautner, V, Tittmann, K. | | 登録日 | 2020-07-28 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
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6ZWF
 | | Neisseria gonorrhoeae transaldolase | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CITRIC ACID, ... | | 著者 | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | | 登録日 | 2020-07-28 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
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6ZX4
 | | Neisseria gonorrhoeae transaldolase | | 分子名称: | CITRIC ACID, GLYCEROL, Transaldolase | | 著者 | Sautner, V, Rabe von Pappenheim, F, Wensien, M, Tittmann, K. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
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6ZWH
 | | Neisseria gonorrhoeae transaldolase at 1.5 Angstrom resolution | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | | 著者 | Rabe von Pappenheim, F, Wensien, M, Funk, L.-M, Sautner, V, Tittmann, K. | | 登録日 | 2020-07-28 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
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7B0L
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7BBW
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7BBX
 | | Neisseria gonorrhoeae transaldolase, variant K8A | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, Transaldolase | | 著者 | Rabe von Pappenheim, F, Wensien, M, Funk, L.M, Tittmann, K. | | 登録日 | 2020-12-18 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Nature, 593, 2021
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5BTM
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3SJ2
 | | A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome | | 分子名称: | ACETATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3') | | 著者 | Kumar, A, Pengfei, F, Park, H, Nettles, K, Guo, M, Disney, M.D. | | 登録日 | 2011-06-20 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome.
Chembiochem, 12, 2011
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3SZX
 | | Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations | | 分子名称: | RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3') | | 著者 | Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D. | | 登録日 | 2011-07-19 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
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3SYW
 | | Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations | | 分子名称: | PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3') | | 著者 | Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D. | | 登録日 | 2011-07-18 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
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7VIC
 | | The crystal structure of SARS-CoV-2 3C-like protease in complex with a traditional Chinese Medicine Inhibitors | | 分子名称: | (1beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R,16beta)-1,6,7,14-tetrahydroxy-7,20-epoxykauran-15-one, 3C-like proteinase | | 著者 | Zhong, B, Chen, B, Zhou, H, Sun, L. | | 登録日 | 2021-09-26 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease.
Small Sci, 2, 2022
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