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6BJI
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Human ABO(H) blood group glycosyltransferase GTA D302C mutant
Descriptor: GLYCEROL, Histo-blood group ABO system transferase
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJK
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Human ABO(H) blood group glycosyltransferase GTB D302C mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJL
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Human ABO(H) blood group glycosyltransferase GTB D302L mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
6BJM
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Human ABO(H) blood group glycosyltransferase GTB R188K mutant
Descriptor: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ...
Authors:Gagnon, S.M.L, Legg, M.S.G, Evans, S.V.
Deposit date:2017-11-06
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
7ST8
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Crystal structure of 7H2.2 Fab in complex with SAS1B C-terminal region
Descriptor: 7H2.2 Fab Heavy Chain, 7H2.2 Fab Light Chain, Astacin-like metalloendopeptidase
Authors:Legg, M.S.G, Evans, S.V.
Deposit date:2021-11-12
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Monoclonal antibody 7H2.2 binds the C-terminus of the cancer-oocyte antigen SAS1B through the hydrophilic face of a conserved amphipathic helix corresponding to one of only two regions predicted to be ordered
Acta Crystallogr.,Sect.D, 78, 2022
7SV6
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Crystal structure of SpaA-SLH/G46A/G109A in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe
Descriptor: Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside
Authors:Legg, M.S.G, Evans, S.V.
Deposit date:2021-11-18
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
7SV4
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Crystal structure of SpaA-SLH in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAc-(1->3)-4,6-Pyr-beta-D-ManNAcOMe
Descriptor: GLYCEROL, Surface (S-) layer glycoprotein, methyl 2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranoside
Authors:Legg, M.S.G, Evans, S.V.
Deposit date:2021-11-18
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
7SV3
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Crystal structure of SpaA-SLH in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe
Descriptor: Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside
Authors:Legg, M.S.G, Evans, S.V.
Deposit date:2021-11-18
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
7SV5
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Crystal structure of SpaA-SLH/G109A in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe
Descriptor: GLYCEROL, Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside
Authors:Legg, M.S.G, Evans, S.V.
Deposit date:2021-11-18
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
7T0H
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Crystal structure of S25-39 Fab Unliganded 2
Descriptor: BROMIDE ION, S25-39 Fab heavy chain, S25-39 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
7T0F
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Crystal structure of S25-39 Fab in complex with 4-MeO-KdoOAll
Descriptor: 3-deoxy-4-O-methyl-alpha-D-manno-oct-2-ulopyranosonic acid, S25-39 Fab heavy chain, S25-39 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
7T0I
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Crystal structure of S25-39 Fab Unliganded 3
Descriptor: S25-39 Fab heavy chain, S25-39 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
7T0J
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Crystal structure of S25-2 Fab Unliganded 3
Descriptor: S25-2 Fab heavy chain, S25-2 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
7T0K
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Crystal structure of S25-2 Fab Unliganded 4
Descriptor: IODIDE ION, S25-2 Fab heavy chain, S25-2 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
7T0G
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Crystal structure of S25-39 Fab Unliganded 1
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S25-39 Fab heavy chain, S25-39 Fab light chain
Authors:Legg, M.S.G, Blackler, R.J, Evans, S.V.
Deposit date:2021-11-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Antigen binding by conformational selection in near-germline antibodies.
J.Biol.Chem., 298, 2022
1I8K
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CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, ...
Authors:Landry, R.C, Klimowicz, A.C, Lavictoire, S.J, Borisova, S, Kottachchi, D.T, Lorimer, I.A, Evans, S.V.
Deposit date:2001-03-14
Release date:2002-03-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.
J.Mol.Biol., 308, 2001
1I8I
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CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT ROOM TEMPERATURE
Descriptor: EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, ...
Authors:Landry, R.C, Klimowicz, A.C, Lavictoire, S.J, Borisova, S, Kottachchi, D.T, Lorimer, I.A, Evans, S.V.
Deposit date:2001-03-14
Release date:2002-03-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.
J.Mol.Biol., 308, 2001
1LZI
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Glycosyltransferase A + UDP + H antigen acceptor
Descriptor: Glycosyltransferase A, MANGANESE (II) ION, MERCURY (II) ION, ...
Authors:Patenaude, S.I, Seto, N.O.L, Borisova, S.N, Szpacenko, A, Marcus, S.L, Palcic, M.M, Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZ0
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Glycosyltransferase A
Descriptor: Glycosyltransferase A, MERCURY (II) ION
Authors:Patenaude, S.I, Seto, N.O.L, Borisova, S.N, Szpacenko, A, Marcus, S.L, Palcic, M.M, Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZ7
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Glycosyltransferase B
Descriptor: Glycosyltransferase B, MERCURY (II) ION
Authors:Patenaude, S.I, Seto, N.O.L, Borisova, S.N, Szpacenko, A, Marcus, S.L, Palcic, M.M, Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1LZJ
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Glycosyltransferase B + UDP + H antigen acceptor
Descriptor: Glycosyltransferase B, MANGANESE (II) ION, MERCURY (II) ION, ...
Authors:Patenaude, S.I, Seto, N.O.L, Borisova, S.N, Szpacenko, A, Marcus, S.L, Palcic, M.M, Evans, S.V.
Deposit date:2002-06-10
Release date:2002-08-28
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:The structural basis for specificity in human ABO(H) blood group biosynthesis.
Nat.Struct.Biol., 9, 2002
1MYT
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BU of 1myt by Molmil
CRYSTAL STRUCTURE TO 1.74 ANGSTROMS RESOLUTION OF METMYOGLOBIN FROM YELLOWFIN TUNA (THUNNUS ALBACARES): AN EXAMPLE OF A MYOGLOBIN LACKING THE D HELIX
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Birnbaum, G.I, Evans, S.V, Przybylska, M, Rose, D.R.
Deposit date:1991-05-06
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:1.70 A resolution structure of myoglobin from yellowfin tuna. An example of a myoglobin lacking the D helix.
Acta Crystallogr.,Sect.D, 50, 1994
1Q9O
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S45-18 Fab Unliganded
Descriptor: MAGNESIUM ION, S45-2 Fab (IgG1k) heavy chain, S45-2 Fab (IgG1k) light chain
Authors:Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
Deposit date:2003-08-25
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
1Q9L
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S25-2 Fab Unliganded 2
Descriptor: MAGNESIUM ION, S25-2 Fab (IgG1k) heavy chain, S25-2 Fab (IgG1k) light chain, ...
Authors:Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
Deposit date:2003-08-25
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003
1Q9W
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S45-18 Fab pentasaccharide bisphosphate complex
Descriptor: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, ...
Authors:Nguyen, H.P, Seto, N.O, MacKenzie, C.R, Brade, L, Kosma, P, Brade, H, Evans, S.V.
Deposit date:2003-08-26
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Germline antibody recognition of distinct carbohydrate epitopes.
Nat.Struct.Biol., 10, 2003

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