1I8I

CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT ROOM TEMPERATURE

Summary for 1I8I

Entry DOI	10.2210/pdb1i8i/pdb
Related	1i8k
Descriptor	EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII PEPTIDE ANTIGEN, ... (4 entities in total)
Functional Keywords	antibody-peptide complex, immunoglobulin fold, peptide antigen, type ii' beta turn, immune system
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	3
Total formula weight	26878.92
Authors	Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V. (deposition date: 2001-03-14, release date: 2002-03-14, Last modification date: 2021-10-27)
Primary citation	Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V. Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII. J.Mol.Biol., 308:883-893, 2001 Cited by PubMed: 11352579 DOI: 10.1006/jmbi.2001.4628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation