1AOX
 
 | | I DOMAIN FROM INTEGRIN ALPHA2-BETA1 | | 分子名称: | INTEGRIN ALPHA 2 BETA, MAGNESIUM ION | | 著者 | Emsley, J, King, S.L, Bergelson, J.M, Liddington, R.C. | | 登録日 | 1997-07-13 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the I domain from integrin alpha2beta1.
J.Biol.Chem., 272, 1997
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1AUQ
 | | A1 DOMAIN OF VON WILLEBRAND FACTOR | | 分子名称: | A1 DOMAIN OF VON WILLEBRAND FACTOR, CADMIUM ION | | 著者 | Emsley, J, Cruz, M, Handin, R, Liddington, R. | | 登録日 | 1997-09-01 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib.
J.Biol.Chem., 273, 1998
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7O2U
 | | PqsR (MvfR) in complex with antagonist 40 | | 分子名称: | 2-[4-[(2S)-3-(6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-propoxy]phenoxy]ethanenitrile, LysR family transcriptional regulator | | 著者 | Emsley, J, Richardson, W. | | 登録日 | 2021-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | PqsR (MvfR) in complex with antagonist 40
To Be Published
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7O2T
 | | PqsR (MvfR) in complex with antagonist 61 | | 分子名称: | 2-[4-[(2S)-3-(6-chloro-4-oxoquinazolin-3-yl)-2-hydroxypropoxy]phenyl]acetonitrile, LysR family transcriptional regulator | | 著者 | Emsley, J, Richardson, W. | | 登録日 | 2021-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | PqsR (MvfR) in complex with antagonist 61
To Be Published
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1Q7D
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1DZI
 | | integrin alpha2 I domain / collagen complex | | 分子名称: | COBALT (II) ION, COLLAGEN, INTEGRIN | | 著者 | Emsley, j, Knight, G, Farndale, R, Barnes, M, Liddington, R. | | 登録日 | 2000-03-01 | | 公開日 | 2001-03-01 | | 最終更新日 | 2017-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis of Collagen Recognition by Integrin Alpha2Beta1
Cell(Cambridge,Mass.), 101, 2000
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1SAC
 | | THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT | | 分子名称: | ACETIC ACID, CALCIUM ION, SERUM AMYLOID P COMPONENT | | 著者 | White, H.E, Emsley, J, O'Hara, B.P, Oliva, G, Srinivasan, N, Tickle, I.J, Blundell, T.L, Pepys, M.B, Wood, S.P. | | 登録日 | 1994-01-27 | | 公開日 | 1994-05-31 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of pentameric human serum amyloid P component.
Nature, 367, 1994
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6EJX
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1GWB
 | | STRUCTURE OF GLYCOPROTEIN 1B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ... | | 著者 | Emsley, J, Uff, S, Clemetson, K.J.M, Clemetson, J.M, Harrison, T. | | 登録日 | 2002-03-14 | | 公開日 | 2003-02-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
J.Biol.Chem., 277, 2002
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2X0C
 | | Crystal Structure of the R7R8 domains of Talin | | 分子名称: | TALIN-1 | | 著者 | Gingras, A.R, Goult, B.T, Bate, N, Barsukov, I.L, Emsley, J, Critchely, D.R. | | 登録日 | 2009-12-08 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-03-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Central Region of Talin Has a Unique Fold that Binds Vinculin and Actin.
J.Biol.Chem., 285, 2010
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7B01
 | | ADAMTS13-CUB12 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Maltodextrin-binding protein,Maltodextrin-binding protein,Maltodextrin-binding protein,ADAMTS13 CUB12,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13,A disintegrin and metalloproteinase with thrombospondin motifs 13, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Kim, H.J, Emsley, J. | | 登録日 | 2020-11-18 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of ADAMTS13 CUB domains reveals their role in global latency.
Sci Adv, 7, 2021
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6I44
 | | Allosteric activation of human prekallikrein by apple domain disc rotation | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | 著者 | Li, C, Pathak, M, MaCrae, K, Dreveny, I, Emsley, J. | | 登録日 | 2018-11-09 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J.Thromb.Haemost., 17, 2019
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6I58
 | | Allosteric activation of human prekallikrein by apple domain disc rotation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Li, C, Pathak, M, McCrae, K, Dreveny, I, Emsley, J. | | 登録日 | 2018-11-13 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J.Thromb.Haemost., 17, 2019
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2I1U
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4XE4
 | | Coagulation Factor XII protease domain crystal structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XII, GLYCEROL | | 著者 | Pathak, M, Wilmann, P, Awford, J, Li, C, Fisher, P.M, Dreveny, I, Dekker, L.V, Emsley, J. | | 登録日 | 2014-12-22 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Coagulation factor XII protease domain crystal structure.
J.Thromb.Haemost., 13, 2015
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4XDE
 | | Coagulation Factor XII protease domain crystal structure | | 分子名称: | CITRATE ANION, Coagulation factor XII, ISOPROPYL ALCOHOL | | 著者 | Pathak, M, Wilmann, P, Awford, J, Li, C, Fisher, P.M, Dreveny, I, Dekker, L.V, Emsley, J. | | 登録日 | 2014-12-19 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Coagulation factor XII protease domain crystal structure.
J.Thromb.Haemost., 13, 2015
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3RFE
 | | Crystal structure of glycoprotein GPIb ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Platelet glycoprotein Ib beta chain, ... | | 著者 | McEwan, P.A, Yang, W, Carr, K.H, Mo, X, Zheng, X, Li, R, Emsley, J. | | 登録日 | 2011-04-06 | | 公開日 | 2011-12-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.245 Å) | | 主引用文献 | Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbbeta and a GPIbbeta/GPIX chimer
Blood, 118, 2011
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3T9L
 | | Structure of N-terminal DUSP-UBL domains of human USP15 | | 分子名称: | SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | | 著者 | Harper, S, Besong, T.M.D, Emsley, J, Scott, D.J, Dreveny, I. | | 登録日 | 2011-08-03 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the USP15 N-Terminal Domains: A beta-Hairpin Mediates Close Association between the DUSP and UBL Domains
Biochemistry, 50, 2011
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3KD0
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7QOT
 | | Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIa heavy chain, Kininogen-1 light chain, ... | | 著者 | Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J. | | 登録日 | 2021-12-28 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
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7QOX
 | | Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | 著者 | Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J. | | 登録日 | 2021-12-29 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI.
J Thromb Haemost, 17, 2019
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2QP2
 | | Structure of a MACPF/perforin-like protein | | 分子名称: | CALCIUM ION, Unknown protein | | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | | 登録日 | 2007-07-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
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2M32
 | | Alpha-1 integrin I-domain in complex with GLOGEN triple helical peptide | | 分子名称: | GLOGEN peptide, Integrin alpha-1, MAGNESIUM ION | | 著者 | Chin, Y, Headey, S, Mohanty, B, McEwan, P, Swarbrick, J, Mulhern, T, Emsley, J, Simpson, J, Scanlon, M. | | 登録日 | 2013-01-07 | | 公開日 | 2013-11-06 | | 最終更新日 | 2014-02-12 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure of Integrin alpha 1I Domain in Complex with a Collagen-mimetic Peptide.
J.Biol.Chem., 288, 2013
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6SZW
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2OWL
 | | Crystal structure of E. coli RdgC | | 分子名称: | CALCIUM ION, Recombination-associated protein rdgC | | 著者 | Briggs, G.S, McEwan, P.A, Yu, J, Moore, T, Emsley, J, Lloyd, R.G. | | 登録日 | 2007-02-16 | | 公開日 | 2007-03-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ring Structure of the Escherichia coli DNA-binding Protein RdgC Associated with Recombination and Replication Fork Repair.
J.Biol.Chem., 282, 2007
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