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4PZS
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BU of 4pzs by Molmil
Crystal structure of p300 histone acetyltransferase domain in complex with Acetyl-Coenzyme A
Descriptor: ACETYL COENZYME *A, DIMETHYL SULFOXIDE, Histone acetyltransferase p300
Authors:Maksimoska, J, Marmorstein, R.
Deposit date:2014-03-31
Release date:2014-06-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues.
Biochemistry, 53, 2014
5TJ8
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BU of 5tj8 by Molmil
Structure of WWP2 WW2-2,3-linker-HECT (no WW2 observed)
Descriptor: NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION
Authors:Chen, Z, Gabelli, S.B.
Deposit date:2016-10-03
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
5TJ7
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BU of 5tj7 by Molmil
Structure of WWP2 WW2-2,3-linker-HECT aa 334-398 linked to 485-865
Descriptor: CHLORIDE ION, NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION, ...
Authors:Chen, Z, Gabelli, S.B.
Deposit date:2016-10-03
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
5TJQ
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BU of 5tjq by Molmil
Structure of WWP2 2,3-linker-HECT
Descriptor: NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2
Authors:Chen, Z, Gabelli, S.B.
Deposit date:2016-10-04
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A Tunable Brake for HECT Ubiquitin Ligases.
Mol. Cell, 66, 2017
7JVX
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BU of 7jvx by Molmil
Crystal structure of PTEN (aa 7-353 followed by spacer TGGGSGGTGGGSGGTGGGCY ligated to peptide pSDpTpTDpSDPENEPFDED)
Descriptor: PHOSPHATE ION, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Dempsey, D, Phan, K, Cole, P, Gabelli, S.B.
Deposit date:2020-08-24
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structural basis of PTEN regulation by multi-site phosphorylation.
Nat.Struct.Mol.Biol., 28, 2021
7JUL
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BU of 7jul by Molmil
Crystal structure of non phosphorylated PTEN (n-crPTEN-13sp-T1, SDTTDSDPENEG)
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Dempsey, D, Phan, K, Cole, P, Gabelli, S.B.
Deposit date:2020-08-20
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The structural basis of PTEN regulation by multi-site phosphorylation.
Nat.Struct.Mol.Biol., 28, 2021
7JTX
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BU of 7jtx by Molmil
the structural basis of PTEN regulation by multi-site phosphorylation
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Park, E, Dempsey, D.R, Cole, P.
Deposit date:2020-08-18
Release date:2021-09-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:The structural basis of PTEN regulation by multi-site phosphorylation.
Nat.Struct.Mol.Biol., 28, 2021
5LY1
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BU of 5ly1 by Molmil
JMJD2A/ KDM4A COMPLEXED WITH NI(II) AND Macrocyclic PEPTIDE Inhibitor CP2 (13-mer)
Descriptor: CHLORIDE ION, CP2, GLYCEROL, ...
Authors:King, O.N.F, Chowdhury, R, Kawamura, A, Schofield, C.J.
Deposit date:2016-09-23
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Nat Commun, 8, 2017
5LY2
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BU of 5ly2 by Molmil
JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Macrocyclic PEPTIDE Inhibitor CP2_R6Kme3 (13-mer)
Descriptor: CHLORIDE ION, CP2_R6Kme3, GLYCEROL, ...
Authors:Chowdhury, R, Madden, S.K, Hopkinson, R, Schofield, C.J.
Deposit date:2016-09-23
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Nat Commun, 8, 2017
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