8V6J
| DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024
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8V5N
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8V5O
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8V6G
| DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (11.16 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024
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8V5M
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1YSM
| NMR Structure of N-terminal domain (Residues 1-77) of Siah-Interacting Protein. | Descriptor: | Calcyclin-binding protein | Authors: | Bhattacharya, S, Lee, Y.T, Michowski, W, Jastrzebska, B, Filipek, A, Kuznicki, J, Chazin, W.J. | Deposit date: | 2005-02-08 | Release date: | 2005-07-26 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies. Biochemistry, 44, 2005
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8V6H
| DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024
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8V6I
| DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (14.06 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024
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2AAO
| Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana | Descriptor: | CALCIUM ION, Calcium-dependent protein kinase, isoform AK1 | Authors: | Chandran, V, Stollar, E.J, Lindorff-Larsen, K, Harper, J.F, Chazin, W.J, Dobson, C.M, Luisi, B.F, Christodoulou, J. | Deposit date: | 2005-07-13 | Release date: | 2005-12-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. J.Mol.Biol., 357, 2006
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2AMI
| Solution Structure Of The Calcium-loaded N-Terminal Sensor Domain Of Centrin | Descriptor: | Caltractin | Authors: | Hu, H.T, Fagan, P.A, Bunick, C.G, Sheehan, J.H, Chazin, W.J. | Deposit date: | 2005-08-09 | Release date: | 2005-08-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the N-terminal calcium sensor domain of centrin reveals the biochemical basis for domain-specific function. J.Biol.Chem., 281, 2006
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1KCY
| NMR solution structure of apo calbindin D9k (F36G + P43M mutant) | Descriptor: | calbindin D9k | Authors: | Nelson, M.R, Thulin, E, Fagan, P.A, Forsen, S, Chazin, W.J. | Deposit date: | 2001-11-12 | Release date: | 2001-11-21 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | The EF-hand domain: a globally cooperative structural unit. Protein Sci., 11, 2002
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8S9W
| Murine S100A7/S100A15 in presence of calcium | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Harrison, S.A, Naretto, A, Balakrishnan, S, Chazin, W.J. | Deposit date: | 2023-03-30 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7. J.Biol.Chem., 299, 2023
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8U5Y
| human RADX trimer bound to ssDNA | Descriptor: | DNA (25-MER), RPA-related protein RADX | Authors: | Balakrishnan, S, Chazin, W.J. | Deposit date: | 2023-09-13 | Release date: | 2023-10-11 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Biorxiv, 2023
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8U61
| Human RADX tetramer bound to ssDNA | Descriptor: | RPA-related protein RADX, dT25 DNA (25-MER) | Authors: | Balakrishnan, S, Chazin, W.J. | Deposit date: | 2023-09-13 | Release date: | 2024-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Proc.Natl.Acad.Sci.USA, 121, 2024
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1CB1
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1CNP
| THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES | Descriptor: | CALCYCLIN (RABBIT, APO) | Authors: | Potts, B.C.M, Smith, J, Akke, M, Macke, T.J, Okazaki, K, Hidaka, H, Case, D.A, Chazin, W.J. | Deposit date: | 1995-08-31 | Release date: | 1996-10-14 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | The structure of calcyclin reveals a novel homodimeric fold for S100 Ca(2+)-binding proteins. Nat.Struct.Biol., 2, 1995
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2JTT
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2KEB
| NMR solution structure of the N-terminal domain of the DNA polymerase alpha p68 subunit | Descriptor: | DNA polymerase subunit alpha B | Authors: | Huang, H, Weiner, B.E, Zhang, H, Fuller, B.E, Gao, Y, Wile, B.M, Chazin, W.J, Fanning, E. | Deposit date: | 2009-01-28 | Release date: | 2010-02-02 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. J.Biol.Chem., 285, 2010
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2KBI
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2KWQ
| Mcm10 C-terminal DNA binding domain | Descriptor: | Protein MCM10 homolog, ZINC ION | Authors: | Robertson, P.D, Chagot, B, Chazin, W.J, Eichman, B.F. | Deposit date: | 2010-04-15 | Release date: | 2010-05-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif. J.Biol.Chem., 285, 2010
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2L53
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1OQP
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1PSB
| Solution structure of calcium loaded S100B complexed to a peptide from N-Terminal regulatory domain of NDR kinase. | Descriptor: | Ndr Ser/Thr kinase-like protein, S-100 protein, beta chain | Authors: | Bhattacharya, S, Large, E, Heizmann, C.W, Hemmings, B, Chazin, W.J. | Deposit date: | 2003-06-21 | Release date: | 2003-12-16 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structure of the Ca(2+)/S100B/NDR Kinase Peptide Complex: Insights into S100 Target Specificity and Activation of the Kinase. Biochemistry, 42, 2003
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1QMS
| Head-to-Tail Dimer of Calicheamicin gamma-1-I Oligosaccharide Bound to DNA Duplex, NMR, 9 Structures | Descriptor: | CALICHEAMICIN GAMMA-1-OLIGOSACCHARIDE, DNA (5'-D(*GP*CP*AP*CP*CP*TP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*AP*GP*GP*TP*GP*C)-3'), ... | Authors: | Bifulco, G, Galeone, A, Nicolaou, K.C, Chazin, W.J, Gomez-Paloma, L. | Deposit date: | 1999-10-06 | Release date: | 1999-10-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(ACCT) and D(TCCT) High-Affinity Binding Sites J.Am.Chem.Soc., 120, 1998
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1QX2
| X-ray Structure of Calcium-loaded Calbindomodulin (A Calbindin D9k Re-engineered to Undergo a Conformational Opening) at 1.44 A Resolution | Descriptor: | CALCIUM ION, Vitamin D-dependent calcium-binding protein, intestinal, ... | Authors: | Bunick, C.G, Nelson, M.R, Mangahas, S, Mizoue, L.S, Bunick, G.J, Chazin, W.J. | Deposit date: | 2003-09-04 | Release date: | 2004-05-25 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Designing Sequence to Control Protein Function in an EF-Hand Protein J.Am.Chem.Soc., 126, 2004
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