1QCQ
| UBIQUITIN CONJUGATING ENZYME | 分子名称: | PROTEIN (UBIQUITIN CONJUGATING ENZYME) | 著者 | Cook, W.J, Jeffrey, L.C, Xu, Y, Chau, V. | 登録日 | 1999-05-10 | 公開日 | 1999-05-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4. Biochemistry, 32, 1993
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2UCZ
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4IKF
| PFV intasome with inhibitor MB-76 | 分子名称: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | 著者 | Taltynov, O, Demeulemeester, J, Desimmie, B.A, Suchaud, V, Billamboz, M, Lion, C, Bailly, F, Debyser, Z, Cotelle, P, Christ, F, Strelkov, S.V. | 登録日 | 2012-12-26 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | 2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), novel inhibitors of HIV integrase with a high barrier to resistance. Acs Chem.Biol., 8, 2013
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6UTL
| Yeast Thiol Specific antoxidant 2 with C171S mutation and catalytic cysteine alkylated with iodoacetamide | 分子名称: | Peroxiredoxin TSA2 | 著者 | Tairum, C.A, Bannitz-Fernandes, R, Tonoli, C.C.C, Murakami, M.T, de Oliveira, M.A, Netto, L.E.S. | 登録日 | 2019-10-29 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependent to alternative redox pathways. Free Radic Biol Med, 156, 2020
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1RCM
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1YR9
| PAB0955 crystal structure : a GTPase in GDP and PO4 bound form from Pyrococcus abyssi | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2005-02-03 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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1YR7
| PAB0955 crystal structure : a GTPase in GTP-gamma-S bound form from Pyrococcus abyssi | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ATP(GTP)binding protein | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2005-02-03 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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1YRB
| PAB0955 crystal structure : a GTPase in GDP and Mg bound form from Pyrococcus abyssi | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2005-02-03 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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1YR8
| PAB0955 crystal structure : a GTPase in GTP bound form from Pyrococcus abyssi | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2005-02-03 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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1YRA
| PAB0955 crystal structure : a GTPase in GDP bound form from Pyrococcus abyssi | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-DIPHOSPHATE | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2005-02-03 | 公開日 | 2006-02-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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1YR6
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7F8P
| Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with new carbapenem drug T203 | 分子名称: | (2R,3R)-3-methyl-4-(2-oxidanylidene-2-propan-2-yloxy-ethyl)sulfanyl-2-[(2R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydro-1H-pyrrole-5-carboxylic acid, (4R,5S,6S)-6-((R)-1-hydroxyethyl)-3-((2-isopropoxy-2-oxoethyl)thio)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, GLUTAMIC ACID, ... | 著者 | Kumar, P, Lamichhane, G. | 登録日 | 2021-07-02 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase. Elife, 11, 2022
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7F71
| Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with peptidoglycan sugar moiety and glutamate | 分子名称: | GLUTAMIC ACID, GLYCEROL, L,D-transpeptidase 2, ... | 著者 | Kumar, P, Lamichhane, G. | 登録日 | 2021-06-26 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase. Elife, 11, 2022
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3FT8
| Structure of HSP90 bound with a noval fragment. | 分子名称: | (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime, Heat shock protein HSP 90-alpha | 著者 | Barker, J.B, Cheng, R.K.Y, Palan, S, Felicetti, B. | 登録日 | 2009-01-12 | 公開日 | 2009-06-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fragment-based identification of Hsp90 inhibitors. Chemmedchem, 4, 2009
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3FT5
| Structure of HSP90 bound with a novel fragment | 分子名称: | 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine, Heat shock protein HSP 90-alpha | 著者 | Barker, J.B, Mather, O, Cheng, R.K.Y, Palan, S, Felicetti, B. | 登録日 | 2009-01-12 | 公開日 | 2009-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fragment-based Identification of Hsp90 Inhibitors. Chemmedchem, 4, 2009
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7XXN
| HapR Quadruple mutant, bound to Qstatin | 分子名称: | 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, GLYCEROL, Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-05-30 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7XY0
| HapR Double mutant Y76F, F171C | 分子名称: | Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-05-31 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7XXS
| HapR mutant I141V | 分子名称: | Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-05-30 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7XXO
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7XY5
| HapR_Double Mutant with CHES buffer | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-05-31 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7XXT
| HapR Quadruple mutant, bound to IMTVC-212 | 分子名称: | 1-((5-phenylthiophen-2-yl)sulfonyl)-1H-pyrazole, DIMETHYL SULFOXIDE, Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-05-30 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7Y4J
| HapR_Triple mutant Y76F, L97I, F171C | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-06-14 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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7XYI
| HapR Quadruple mutant Y76F, L97I, I141V, F171C | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hemagglutinin/protease regulatory protein | 著者 | Basu Choudhury, G, Chaudhari, V, Ray Chaudhuri, S, Datta, S. | 登録日 | 2022-06-01 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233, 2023
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5UWV
| Crystal structure of Mycobacterium abscessus L,D-transpeptidase 2 | 分子名称: | L,D-TRANSPEPTIDASE 2 | 著者 | Kumar, P, Ginell, S.L, Lamichhane, G. | 登録日 | 2017-02-21 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins. Antimicrob. Agents Chemother., 61, 2017
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2OXR
| PAB0955 crystal structure : a GTPase in GDP and Mg bound form from Pyrococcus abyssi (after GTP hydrolysis) | 分子名称: | ATP(GTP)binding protein, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Gras, S, Carpentier, P, Armengaud, J, Housset, D. | 登録日 | 2007-02-21 | 公開日 | 2007-04-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into a new homodimeric self-activated GTPase family. Embo Rep., 8, 2007
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