7XXN

HapR Quadruple mutant, bound to Qstatin

Summary for 7XXN

Entry DOI	10.2210/pdb7xxn/pdb
Descriptor	Hemagglutinin/protease regulatory protein, 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, GLYCEROL, ... (4 entities in total)
Functional Keywords	hapr master regulator, transcription
Biological source	Vibrio cholerae
Total number of polymer chains	1
Total formula weight	24033.59
Authors	Basu Choudhury, G.,Chaudhari, V.,Ray Chaudhuri, S.,Datta, S. (deposition date: 2022-05-30, release date: 2023-02-22, Last modification date: 2023-11-29)
Primary citation	Sen, H.,Choudhury, G.B.,Pawar, G.,Sharma, Y.,Bhalerao, S.E.,Chaudhari, V.D.,Datta, S.,Raychaudhuri, S. Diversity in the ligand binding pocket of HapR attributes to its uniqueness towards several inhibitors with respect to other homologues - A structural and molecular perspective. Int.J.Biol.Macromol., 233:123495-123495, 2023 Cited by PubMed: 36739058 DOI: 10.1016/j.ijbiomac.2023.123495 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation