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6D3G
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BU of 6d3g by Molmil
PER-2 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 2.4 Angstrom resolution
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, TETRAETHYLENE GLYCOL
著者Power, P, Ruggiero, M, Gutkind, G, Bonomo, R, Klinke, S.
登録日2018-04-16
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam.
Antimicrob.Agents Chemother., 63, 2019
6DGU
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BU of 6dgu by Molmil
PER-2 class A extended-spectrum beta-lactamase crystal structure at 2.69 Angstrom resolution
分子名称: Beta-lactamase
著者Power, P, Ruggiero, M, Gutkind, G, Bonomo, R, Klinke, S.
登録日2018-05-18
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam.
Antimicrob.Agents Chemother., 63, 2019
6C6I
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BU of 6c6i by Molmil
Crystal structure of a chimeric NDM-1 metallo-beta-lactamase harboring the IMP-1 L3 loop
分子名称: Metallo-beta-lactamase type 2 chimera, ZINC ION
著者Otero, L, Giannini, E, Klinke, S, Palacios, A, Mojica, M, Bonomo, R, Llarrull, L, Vila, A.
登録日2018-01-18
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Reaction Mechanism of Metallo-beta-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop.
Antimicrob. Agents Chemother., 63, 2019
6CAC
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BU of 6cac by Molmil
Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue in L3 loop
分子名称: CADMIUM ION, CALCIUM ION, COBALT (II) ION, ...
著者Alzari, P.M, Giannini, E, Palacios, A, Mojica, M, Bonomo, R, Llarrull, L, Vila, A.
登録日2018-01-30
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献The Reaction Mechanism of Metallo-beta-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop.
Antimicrob. Agents Chemother., 63, 2019
4JLF
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BU of 4jlf by Molmil
Inhibitor resistant (R220A) substitution in the Mycobacterium tuberculosis beta-lactamase
分子名称: Beta-lactamase, PHOSPHATE ION
著者Hazra, S, Kurz, S, Blanchard, J, Bonomo, R.
登録日2013-03-12
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Can inhibitor-resistant substitutions in the Mycobacterium tuberculosis beta-Lactamase BlaC lead to clavulanate resistance?: a biochemical rationale for the use of beta-lactam-beta-lactamase inhibitor combinations.
Antimicrob.Agents Chemother., 57, 2013

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件を2024-04-24に公開中

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