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1YVJ
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BU of 1yvj by Molmil
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, Tyrosine-protein kinase JAK3
著者Boggon, T.J, Li, Y, Manley, P.W, Eck, M.J.
登録日2005-02-15
公開日2005-05-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog
Blood, 106, 2005
233D
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BU of 233d by Molmil
THE CRYSTAL STRUCTURE ANALYSIS OF D(CGCGAASSCGCG)2: A SYNTHETIC DNA DODECAMER DUPLEX CONTAINING FOUR 4'-THIO-2'-DEOXYTHYMIDINE NUCLEOTIDES
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*)-D(*(T49)P*(T49)P*)-D(*CP*GP*CP*G)-3')
著者Boggon, T.J, Hancox, E.L, McAuley-Hecht, K.E, Connolly, B.A, Hunter, W.N, Brown, T, Walker, R.T, Leonard, G.A.
登録日1995-10-16
公開日1996-06-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.
Nucleic Acids Res., 24, 1996
1L3W
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BU of 1l3w by Molmil
C-cadherin Ectodomain
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L.
登録日2002-03-01
公開日2002-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献C-cadherin ectodomain structure and implications for cell adhesion mechanisms
Science, 296, 2002
1C8Z
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BU of 1c8z by Molmil
C-TERMINAL DOMAIN OF MOUSE BRAIN TUBBY PROTEIN
分子名称: PHOSPHATE ION, TUBBY PROTEIN
著者Boggon, T.J, Myers, S.C, Shapiro, L.
登録日1999-07-30
公開日1999-12-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Implication of tubby proteins as transcription factors by structure-based functional analysis.
Science, 286, 1999
4WJ7
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BU of 4wj7 by Molmil
CCM2 PTB domain in complex with KRIT1 NPxY/F3
分子名称: KRIT1 NPxY/F3, Malcavernin
著者Fisher, O.S, Liu, W, Zhang, R, Stiegler, A.L, Boggon, T.J.
登録日2014-09-29
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
J.Biol.Chem., 290, 2015
8DGQ
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BU of 8dgq by Molmil
Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide
分子名称: MALONATE ION, Ras GTPase-activating protein 1, Rho GTPase-activating protein 35
著者Stiegler, A.L, Vish, K.J, Boggon, T.J.
登録日2022-06-24
公開日2022-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP.
Structure, 30, 2022
8GI4
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BU of 8gi4 by Molmil
Crystal structure of human LIMK2 PDZ domain
分子名称: LIM domain kinase 2
著者Casanova Sepulveda, G, Boggon, T.J.
登録日2023-03-13
公開日2023-12-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Autoregulation of the LIM kinases by their PDZ domain
Nat Commun, 14, 2023
6BHC
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BU of 6bhc by Molmil
Crystal structure of pseduokinase PEAK1 (Sugen Kinase 269)
分子名称: Pseudopodium-enriched atypical kinase 1
著者Ha, B.H, Boggon, T.J.
登録日2017-10-30
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization.
J. Biol. Chem., 293, 2018
6D4G
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N-GTPase domain of p190RhoGAP-A
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 35
著者Stiegler, A.L, Boggon, T.J.
登録日2018-04-18
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase.
Structure, 26, 2018
3F6Q
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BU of 3f6q by Molmil
Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain
分子名称: IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ...
著者Chiswell, B.P, Calderwood, D.A, Boggon, T.J.
登録日2008-11-06
公開日2008-12-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structural basis of integrin-linked kinase-PINCH interactions.
Proc.Natl.Acad.Sci.USA, 105, 2008
6PXB
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BU of 6pxb by Molmil
N-Terminal SH2 domain of the p120RasGAP
分子名称: Ras GTPase-activating protein 1
著者Jaber Chehayeb, R, Stiegler, A.L, Boggon, T.J.
登録日2019-07-25
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide.
Plos One, 14, 2019
1I7E
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BU of 1i7e by Molmil
C-Terminal Domain Of Mouse Brain Tubby Protein bound to Phosphatidylinositol 4,5-bis-phosphate
分子名称: L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE, TUBBY PROTEIN
著者Santagata, S, Boggon, T.J, Baird, C.L, Shan, W.S, Shapiro, L.
登録日2001-03-08
公開日2001-06-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献G-protein signaling through tubby proteins.
Science, 292, 2001
6PXC
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BU of 6pxc by Molmil
N-Terminal SH2 domain of the p120RasGAP bound to a p190RhoGAP phosphotyrosine peptide
分子名称: Ras GTPase-activating protein 1, phosphopeptide of p190RhoGAP
著者Jaber Chehayeb, R, Stiegler, A.L, Boggon, T.J.
登録日2019-07-25
公開日2019-12-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide.
Plos One, 14, 2019
5D68
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BU of 5d68 by Molmil
Crystal structure of KRIT1 ARD-FERM
分子名称: Krev interaction trapped protein 1
著者Zhang, R, Li, X, Boggon, T.J.
登録日2015-08-11
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
4TKN
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BU of 4tkn by Molmil
Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1
分子名称: Krev interaction trapped protein 1, Sorting nexin-17
著者Stiegler, A.L, Zhang, R, Liu, W, Boggon, T.J.
登録日2014-05-27
公開日2014-07-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
J.Biol.Chem., 289, 2014
4TVQ
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BU of 4tvq by Molmil
CCM3 in complex with CCM2 LD-like motif
分子名称: Cerebral cavernous malformations 2 protein, Cerebral cavernous malformations 3 protein
著者Li, X, Zhang, R, Fisher, O.S, Boggon, T.J.
登録日2014-06-27
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CCM2-CCM3 interaction stabilizes their protein expression and permits endothelial network formation.
J.Cell Biol., 208, 2015
7LO0
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BU of 7lo0 by Molmil
Structure of human ASF1a in complex with a TLK2 peptide
分子名称: Histone chaperone ASF1A, Serine/threonine-protein kinase tousled-like 2
著者Simon, B, Calderwood, D, Turk, B.E, Boggon, T.J.
登録日2021-02-08
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
7LNY
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BU of 7lny by Molmil
Apo structure of the Histone chaperone ASF1A residues 1-155
分子名称: Histone chaperone ASF1A
著者Simon, B, Boggon, T.J, Calderwood, D, Turk, B.E.
登録日2021-02-08
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry.
Nat Commun, 13, 2022
5HVJ
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BU of 5hvj by Molmil
Crystal structure of LIMK1 D460N mutant in complex with AMP-PNP
分子名称: LIM domain kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Hamill, S, Boggon, T.J.
登録日2016-01-28
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Mol.Cell, 62, 2016
5HVK
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BU of 5hvk by Molmil
Crystal structure of LIMK1 mutant D460N in complex with full-length cofilin-1
分子名称: Cofilin-1, LIM domain kinase 1, MAGNESIUM ION, ...
著者Hamill, S, Boggon, T.J.
登録日2016-01-28
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Mol.Cell, 62, 2016
3RQF
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BU of 3rqf by Molmil
Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD2
分子名称: Paxillin LD2 peptide, Programmed cell death protein 10
著者Li, X, Zhang, R, Boggon, T.J.
登録日2011-04-28
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem., 286, 2011
3RQG
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Cerebral cavernous malformation 3 (CCM3) in complex with paxillin LD4
分子名称: Paxillin LD4 peptide, Programmed cell death protein 10
著者Li, X, Zhang, R, Boggon, T.J.
登録日2011-04-28
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem., 286, 2011
4XLI
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BU of 4xli by Molmil
Crystal structure of Abl2/Arg kinase in complex with dasatinib
分子名称: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Non-specific protein-tyrosine kinase, ZINC ION
著者Ha, B.H, Boggon, T.J.
登録日2015-01-13
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the ABL2/ARG kinase in complex with dasatinib.
Acta Crystallogr.,Sect.F, 71, 2015
4Y5O
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CCM2 HHD in complex with MEKK3 NPB1
分子名称: Malcavernin, Mitogen-activated protein kinase kinase kinase 3
著者Fisher, O.S, Boggon, T.J.
登録日2015-02-11
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
Nat Commun, 6, 2015
1OBU
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BU of 1obu by Molmil
Apocrustacyanin C1 crystals grown in space and earth using vapour diffusion geometry
分子名称: CRUSTACYANIN C1 SUBUNIT
著者Habash, J, Boggon, T.J, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
登録日2003-01-31
公開日2003-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Apocrustacyanin C(1) Crystals Grown in Space and on Earth Using Vapour-Diffusion Geometry: Protein Structure Refinements and Electron-Density Map Comparisons
Acta Crystallogr.,Sect.D, 59, 2003

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