8DGQ
Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide
Summary for 8DGQ
Entry DOI | 10.2210/pdb8dgq/pdb |
Descriptor | Ras GTPase-activating protein 1, Rho GTPase-activating protein 35, MALONATE ION, ... (4 entities in total) |
Functional Keywords | sh2 domain, sh3 domain, phosphotyrosine, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 70344.11 |
Authors | Stiegler, A.L.,Vish, K.J.,Boggon, T.J. (deposition date: 2022-06-24, release date: 2022-11-02, Last modification date: 2023-11-15) |
Primary citation | Stiegler, A.L.,Vish, K.J.,Boggon, T.J. Tandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP. Structure, 30:1603-1614.e5, 2022 Cited by PubMed: 36417908DOI: 10.1016/j.str.2022.10.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)