3MEX
| Crystal structure of MexR in oxidized state | Descriptor: | Multidrug resistance operon repressor | Authors: | Chen, H, Yi, C, Zhang, J, Zhang, W, Yang, C.-G, He, C. | Deposit date: | 2010-04-01 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR Embo Rep., 11, 2010
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2LNX
| Solution structure of Vav2 SH2 domain | Descriptor: | Guanine nucleotide exchange factor VAV2 | Authors: | Wu, B, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2012-01-05 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
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2L97
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2AX5
| Solution Structure of Urm1 from Saccharomyces Cerevisiae | Descriptor: | Hypothetical 11.0 kDa protein in FAA3-MAS3 intergenic region | Authors: | Xu, J, Huang, H, Zhang, J, Wu, J, Shi, Y. | Deposit date: | 2005-09-03 | Release date: | 2006-06-27 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of Urm1 and its implications for the origin of protein modifiers. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4URT
| The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R. | Deposit date: | 2014-07-02 | Release date: | 2014-09-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue Neuron, 83, 2014
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6WXK
| PHF23 PHD Domain Apo | Descriptor: | PHD finger protein 23, ZINC ION | Authors: | Vann, K.R, Zhang, J, Zhang, Y, Kutateladze, T. | Deposit date: | 2020-05-11 | Release date: | 2020-07-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun, 11, 2020
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2MLB
| NMR solution structure of a computational designed protein based on template of human erythrocytic ubiquitin | Descriptor: | redesigned ubiquitin | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-02-21 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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2MN4
| NMR solution structure of a computational designed protein based on structure template 1cy5 | Descriptor: | Computational designed protein based on structure template 1cy5 | Authors: | Xiong, P, Wang, M, Zhang, J, Chen, Q, Liu, H. | Deposit date: | 2014-03-28 | Release date: | 2014-10-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability Nat Commun, 5, 2014
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7MT2
| Mtb 70S initiation complex | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-12 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MU0
| MtbEttA in the ADP bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Energy-dependent translational throttle protein EttA, MAGNESIUM ION | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-14 | Release date: | 2022-02-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MSM
| Mtb 70SIC in complex with MtbEttA at Trans_R0 state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-11 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MSZ
| Mtb 70SIC in complex with MtbEttA at Trans_R1 state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-12 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MSH
| Mtb 70SIC in complex with MtbEttA at Pre_R1 state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-11 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MSC
| Mtb 70SIC in complex with MtbEttA at Pre_R0 state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-11 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MT7
| Mtb 70S with P and E site tRNAs | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-13 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7MT3
| Mtb 70S with P/E tRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Cui, Z, Zhang, J. | Deposit date: | 2021-05-12 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
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4WCW
| Ribosomal silencing factor during starvation or stationary phase (RsfS) from Mycobacterium tuberculosis | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Ribosomal silencing factor RsfS | Authors: | Li, X, Sun, Q, Jiang, C, Yang, K, Hung, L, Zhang, J, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2014-09-05 | Release date: | 2014-09-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Ribosomal Silencing Factor Bound to Mycobacterium tuberculosis Ribosome. Structure, 23, 2015
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2M80
| Solution structure of yeast dithiol glutaredoxin Grx8 | Descriptor: | Glutaredoxin-8 | Authors: | Tang, Y, Zhang, J, Yu, J, Wu, J, Zhou, C.Z, Shi, Y. | Deposit date: | 2013-05-02 | Release date: | 2014-05-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure-guided activity enhancement and catalytic mechanism of yeast grx8 Biochemistry, 53, 2014
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5KIP
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7CL0
| Crystal structure of human SIRT6 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... | Authors: | Song, K, Zhang, J. | Deposit date: | 2020-07-20 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Reply to: Binding site for MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
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7CL1
| Human SIRT6 in complex with allosteric activator MDL-801 (3.2A) | Descriptor: | 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Song, K, Zhang, J. | Deposit date: | 2020-07-20 | Release date: | 2021-02-24 | Last modified: | 2021-05-12 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Reply to: Binding site for MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
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4K47
| Structure of the Streptococcus pneumoniae leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | Descriptor: | Leucine--tRNA ligase, SULFATE ION, [(1R,5R,6R,8S)-6-(6-aminopurin-9-yl)-3'-[(R)-oxidanyl(phenyl)methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,9'-8-oxa-9-boranuidabicyclo[4.3.0]nona-1,3,5-triene]-8-yl]methyl dihydrogen phosphate | Authors: | Hu, Q.H, Liu, R.J, Fang, Z.P, Zhang, J, Ding, Y.Y, Tan, M, Wang, M, Pan, W, Zhou, H.C, Wang, E.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase Sci Rep, 3, 2013
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4K48
| Structure of the Streptococcus pneumoniae leucyl-tRNA synthetase editing domain | Descriptor: | Leucine--tRNA ligase | Authors: | Hu, Q.H, Liu, R.J, Fang, Z.P, Zhang, J, Ding, Y.Y, Tan, M, Wang, M, Pan, W, Zhou, H.C, Wang, E.D. | Deposit date: | 2013-04-12 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase Sci Rep, 3, 2013
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8U2B
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6DU8
| Human Polycsytin 2-l1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | Authors: | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | Deposit date: | 2018-06-20 | Release date: | 2018-07-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Cryo-EM structure of the polycystin 2-l1 ion channel. Elife, 7, 2018
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