5HGA
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![BU of 5hga by Molmil](/molmil-images/mine/5hga) | HLA*A2402 complex with HIV nef138 Y2F-8mer mutant epitope | Descriptor: | 8-mer from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2016-01-08 | Release date: | 2016-06-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation. Cell Rep, 15, 2016
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7YV8
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![BU of 7yv8 by Molmil](/molmil-images/mine/7yv8) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ... | Authors: | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2022-08-18 | Release date: | 2023-07-19 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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7YVU
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![BU of 7yvu by Molmil](/molmil-images/mine/7yvu) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2022-08-19 | Release date: | 2023-07-19 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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5IY3
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![BU of 5iy3 by Molmil](/molmil-images/mine/5iy3) | Zika Virus Non-structural Protein NS1 | Descriptor: | Genome polyprotein | Authors: | Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2016-03-23 | Release date: | 2016-04-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses Nat.Struct.Mol.Biol., 23, 2016
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5JHL
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![BU of 5jhl by Molmil](/molmil-images/mine/5jhl) | Crystal structure of zika virus envelope protein in complex with a flavivirus broadly-protective antibody | Descriptor: | Antibody Heavy chain, antibody Light chain, envelope protein | Authors: | Dai, L, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2016-04-21 | Release date: | 2016-05-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody. Cell Host Microbe, 19, 2016
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5JHM
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![BU of 5jhm by Molmil](/molmil-images/mine/5jhm) | |
5H5N
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![BU of 5h5n by Molmil](/molmil-images/mine/5h5n) | |
5GRJ
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![BU of 5grj by Molmil](/molmil-images/mine/5grj) | Crystal structure of human PD-L1 with monoclonal antibody avelumab | Descriptor: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | Authors: | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | Deposit date: | 2016-08-11 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.206 Å) | Cite: | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell Res., 27, 2017
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6AEE
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![BU of 6aee by Molmil](/molmil-images/mine/6aee) | Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G | Descriptor: | 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Wang, Q, Song, H, Qi, J, Gao, G.F. | Deposit date: | 2018-08-04 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.303 Å) | Cite: | Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex. Cell. Mol. Immunol., 2019
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6A7W
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![BU of 6a7w by Molmil](/molmil-images/mine/6a7w) | Structure of a catalytic domain of the colistin resistance enzyme | Descriptor: | Putative integral membrane protein, ZINC ION | Authors: | Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F. | Deposit date: | 2018-07-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.988 Å) | Cite: | Structural and functional insights into MCR-2 mediated colistin resistance. Sci China Life Sci, 61, 2018
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6AED
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![BU of 6aed by Molmil](/molmil-images/mine/6aed) | |
6BR6
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![BU of 6br6 by Molmil](/molmil-images/mine/6br6) | N2 neuraminidase in complex with a novel antiviral compound | Descriptor: | (1R)-4-acetamido-3-amino-1,5-anhydro-2,3,4-trideoxy-1-sulfo-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Li, L.H, Ve, T, Pascolutti, M, Hadhazi, A, Bailly, B, Thomson, R.J, Gao, G.F, von Itzstein, M. | Deposit date: | 2017-11-30 | Release date: | 2018-03-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.03983879 Å) | Cite: | A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity. ChemMedChem, 13, 2018
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6BR5
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![BU of 6br5 by Molmil](/molmil-images/mine/6br5) | N2 neuraminidase in complex with a novel antiviral compound | Descriptor: | (1R)-4-acetamido-1,5-anhydro-3-carbamimidamido-2,3,4-trideoxy-1-sulfo-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, L.H, Ve, T, Pascolutti, M, Hadhazi, A, Bailly, B, Thomson, R.J, Gao, G.F, von Itzstein, M. | Deposit date: | 2017-11-30 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.0379076 Å) | Cite: | A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity. ChemMedChem, 13, 2018
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5H3X
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![BU of 5h3x by Molmil](/molmil-images/mine/5h3x) | |
5E00
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![BU of 5e00 by Molmil](/molmil-images/mine/5e00) | Structure of HLA-A2 P130 | Descriptor: | Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ... | Authors: | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | Deposit date: | 2015-09-26 | Release date: | 2017-01-18 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress. J. Virol., 92, 2018
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5H3W
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![BU of 5h3w by Molmil](/molmil-images/mine/5h3w) | |
3NSS
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![BU of 3nss by Molmil](/molmil-images/mine/3nss) | The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active sites | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Li, Q, Qi, J.X, Zhang, W, Vavricka, C.J, Shi, Y, Gao, G.F. | Deposit date: | 2010-07-02 | Release date: | 2010-09-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site Nat.Struct.Mol.Biol., 17, 2010
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3P2T
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![BU of 3p2t by Molmil](/molmil-images/mine/3p2t) | Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, SULFATE ION | Authors: | Chen, Y, Nam, G, Cheng, H, Zhang, J.H, Willcox, B.E, Gao, G.F. | Deposit date: | 2010-10-04 | Release date: | 2011-03-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance J.Biol.Chem., 286, 2011
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3Q2C
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![BU of 3q2c by Molmil](/molmil-images/mine/3q2c) | Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e) | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily A member 3 | Authors: | Ryu, M, Chen, Y, Qi, J.X, Liu, J, Shi, Y, Cheng, H, Gao, G.F. | Deposit date: | 2010-12-20 | Release date: | 2011-07-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence Plos One, 6, 2011
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8WP8
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![BU of 8wp8 by Molmil](/molmil-images/mine/8wp8) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | Deposit date: | 2023-10-09 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 To Be Published
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8WOY
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![BU of 8woy by Molmil](/molmil-images/mine/8woy) | Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | Deposit date: | 2023-10-08 | Release date: | 2023-12-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency. Mbio, 15, 2024
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8WOZ
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![BU of 8woz by Molmil](/molmil-images/mine/8woz) | Cryo-EM structure of SARS-CoV RBD in complex with rabbit ACE2 | Descriptor: | Angiotensin-converting enzyme, Spike protein S1, ZINC ION | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | Deposit date: | 2023-10-08 | Release date: | 2023-12-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency. Mbio, 15, 2024
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8WOX
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![BU of 8wox by Molmil](/molmil-images/mine/8wox) | Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with rabbit ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | Deposit date: | 2023-10-08 | Release date: | 2023-12-13 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency. Mbio, 15, 2024
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8Y16
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![BU of 8y16 by Molmil](/molmil-images/mine/8y16) | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | Deposit date: | 2024-01-23 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Spike structures, receptor binding and immune escape of SARS-CoV-2 Omicron recently-circulating BA.2.86.1, JN.1, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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8XLV
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![BU of 8xlv by Molmil](/molmil-images/mine/8xlv) | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | Deposit date: | 2023-12-26 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis of receptor binding and immune escape for SARS-CoV-2 Omicron BA.2.86, EG.5, EG.5.1 and HV.1 sub-variants To Be Published
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