Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4ZT2
DownloadVisualize
BU of 4zt2 by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575)
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ...
Authors:Koh, C.-Y, Hol, W.G.J.
Deposit date:2015-05-14
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors.
Acs Infect Dis., 2, 2016
1UEA
DownloadVisualize
BU of 1uea by Molmil
MMP-3/TIMP-1 COMPLEX
Descriptor: CALCIUM ION, MATRIX METALLOPROTEINASE-3, TISSUE INHIBITOR OF METALLOPROTEINASE-1, ...
Authors:Bode, W, Maskos, K, Gomis-Rueth, F.-X, Nagase, H.
Deposit date:1997-06-06
Release date:1998-10-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.
Nature, 389, 1997
3STO
DownloadVisualize
BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
Descriptor: Serine protease inhibitor
Authors:Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
Deposit date:2011-07-11
Release date:2012-05-30
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
2QFY
DownloadVisualize
BU of 2qfy by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with a-ketoglutarate
Descriptor: 2-OXOGLUTARIC ACID, Isocitrate dehydrogenase [NADP]
Authors:Peng, Y.J, Ding, J.P.
Deposit date:2007-06-28
Release date:2008-07-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
4TZR
DownloadVisualize
BU of 4tzr by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1561
Descriptor: 1-{4-amino-3-[2-(cyclopropyloxy)quinolin-6-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-2-methylpropan-2-ol, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A.
Deposit date:2014-07-10
Release date:2014-08-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
J. Med. Chem., 59, 2016
2QFV
DownloadVisualize
BU of 2qfv by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+)
Descriptor: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Peng, Y.J, Ding, J.P.
Deposit date:2007-06-28
Release date:2008-07-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2QFX
DownloadVisualize
BU of 2qfx by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADPH, a-ketoglutarate and Ca(2+)
Descriptor: 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ...
Authors:Peng, Y.J, Ding, J.P.
Deposit date:2007-06-28
Release date:2008-07-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2QFW
DownloadVisualize
BU of 2qfw by Molmil
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate
Descriptor: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP]
Authors:Peng, Y.J, Ding, J.P.
Deposit date:2007-06-28
Release date:2008-07-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008
2GP4
DownloadVisualize
BU of 2gp4 by Molmil
Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis
Descriptor: 6-phosphogluconate dehydratase
Authors:Schormann, N, Symersky, J, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-04-16
Release date:2006-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of [FeS]cluster-free Apo Form of 6-Phosphogluconate Dehydratase from Shewanella oneidensis
To be Published
2RKI
DownloadVisualize
BU of 2rki by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (RT) in Complex with a triazole derived NNRTI
Descriptor: 4-benzyl-3-[(2-chlorobenzyl)sulfanyl]-5-thiophen-2-yl-4H-1,2,4-triazole, CHLORIDE ION, GLYCEROL, ...
Authors:Lansdon, E.B, Kirschberg, T.A.
Deposit date:2007-10-16
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase-structure-activity relationships and crystallographic analysis.
Bioorg.Med.Chem.Lett., 18, 2008
6V3E
DownloadVisualize
BU of 6v3e by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 30S subunit
Descriptor: 16s Ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2019-11-25
Release date:2020-02-05
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
4ONA
DownloadVisualize
BU of 4ona by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1517
Descriptor: 5-amino-1-tert-butyl-3-(7-ethoxyquinolin-3-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A.
Deposit date:2014-01-28
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold.
ACS Med Chem Lett, 5, 2014
6V3A
DownloadVisualize
BU of 6v3a by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with E-site tRNA
Descriptor: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2019-11-25
Release date:2020-02-05
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
6V3D
DownloadVisualize
BU of 6v3d by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 50S subunit
Descriptor: 23s ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2019-11-25
Release date:2020-02-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
6UJI
DownloadVisualize
BU of 6uji by Molmil
Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant
Descriptor: Protective antigen PA-63
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Bann, J.G.
Deposit date:2019-10-03
Release date:2020-10-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structure of the anthrax protective antigen D425A dominant negative mutant reveals a stalled intermediate state of pore maturation.
J.Mol.Biol., 2022
6V3B
DownloadVisualize
BU of 6v3b by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S in Empty state
Descriptor: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2019-11-25
Release date:2020-02-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
6V39
DownloadVisualize
BU of 6v39 by Molmil
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA
Descriptor: 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Morgan, C.E, Yu, E.W.
Deposit date:2019-11-25
Release date:2020-02-05
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Mbio, 11, 2020
7LRF
DownloadVisualize
BU of 7lrf by Molmil
Netrin-1 in complex with SOS
Descriptor: 1,2-ETHANEDIOL, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ...
Authors:Gupta, M, McDougall, M, Torres, A.M, Stetefeld, J.
Deposit date:2021-02-16
Release date:2022-02-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Nat Commun, 14, 2023
7LER
DownloadVisualize
BU of 7ler by Molmil
Netrin-1 filament assembly
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Netrin-1, ...
Authors:McDougall, M, Gupta, M, Stetefeld, J.
Deposit date:2021-01-14
Release date:2022-02-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (5.99 Å)
Cite:The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Nat Commun, 14, 2023
7N9E
DownloadVisualize
BU of 7n9e by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB34
Descriptor: Nb34 nanobody, Spike glycoprotein
Authors:Sun, D, Zhang, C, Shi, Y.
Deposit date:2021-06-17
Release date:2021-08-04
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9B
DownloadVisualize
BU of 7n9b by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB21
Descriptor: NB21 Nanobody, Spike glycoprotein
Authors:Sun, D, Zhang, C, Shi, Y.
Deposit date:2021-06-17
Release date:2021-08-04
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
7N9A
DownloadVisualize
BU of 7n9a by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS RBD with NB21
Descriptor: Nanobody Nb21, Spike protein S1
Authors:Sun, D, Zhang, C, Shi, Y.
Deposit date:2021-06-17
Release date:2021-08-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes
To Be Published
7N9C
DownloadVisualize
BU of 7n9c by Molmil
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95
Descriptor: Nanobody NB95, Spike glycoprotein
Authors:Sun, D, Zhang, C, Shi, Y.
Deposit date:2021-06-17
Release date:2021-08-04
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
Nat Commun, 12, 2021
8EKY
DownloadVisualize
BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
Descriptor: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
Authors:Su, C.C.
Deposit date:2022-09-22
Release date:2023-05-03
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EOJ
DownloadVisualize
BU of 8eoj by Molmil
Microsomal triglyceride transfer protein
Descriptor: Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase
Authors:Zhang, Z.
Deposit date:2022-10-03
Release date:2023-05-03
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023

221716

PDB entries from 2024-06-26

PDB statisticsPDBj update infoContact PDBjnumon