8GBZ
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![BU of 8gbz by Molmil](/molmil-images/mine/8gbz) | Crystal structure of PC39-55C, an anti-HIV broadly neutralizing antibody | Descriptor: | DI(HYDROXYETHYL)ETHER, PC39-55C Fab heavy chain, PC39-55C Fab light chain | Authors: | Murrell, S, Omorodion, O, Wilson, I.A. | Deposit date: | 2023-02-28 | Release date: | 2023-06-07 | Last modified: | 2023-07-12 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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5NIQ
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![BU of 5niq by Molmil](/molmil-images/mine/5niq) | |
4PM3
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![BU of 4pm3 by Molmil](/molmil-images/mine/4pm3) | |
5BZD
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![BU of 5bzd by Molmil](/molmil-images/mine/5bzd) | |
5BZW
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![BU of 5bzw by Molmil](/molmil-images/mine/5bzw) | |
4HIC
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![BU of 4hic by Molmil](/molmil-images/mine/4hic) | |
4P0Y
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![BU of 4p0y by Molmil](/molmil-images/mine/4p0y) | |
4P0Z
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![BU of 4p0z by Molmil](/molmil-images/mine/4p0z) | |
5CW6
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![BU of 5cw6 by Molmil](/molmil-images/mine/5cw6) | Structure of metal dependent enzyme DrBRCC36 | Descriptor: | DrBRCC36, ZINC ION | Authors: | Zeqiraj, E. | Deposit date: | 2015-07-27 | Release date: | 2015-09-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.193 Å) | Cite: | Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
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5CW4
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![BU of 5cw4 by Molmil](/molmil-images/mine/5cw4) | Structure of CfBRCC36-CfKIAA0157 complex (Selenium Edge) | Descriptor: | BRCA1/BRCA2-containing complex subunit 3, GLYCEROL, Protein FAM175B, ... | Authors: | Zeqiraj, E. | Deposit date: | 2015-07-27 | Release date: | 2015-09-16 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.543 Å) | Cite: | Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
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7D5L
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![BU of 7d5l by Molmil](/molmil-images/mine/7d5l) | Discovery of BMS-986144, a Third Generation, Pan Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection | Descriptor: | NS3/4A Protease, ZINC ION, [1,1,1-tris(fluoranyl)-2-methyl-propan-2-yl] ~{N}-[(1~{S},4~{R},6~{S},7~{Z},11~{R},13~{R},14~{S},18~{R})-13-ethyl-18-(7-fluoranyl-6-methoxy-isoquinolin-1-yl)oxy-11-methyl-4-[(1-methylcyclopropyl)sulfonylcarbamoyl]-2,15-bis(oxidanylidene)-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-en-14-yl]carbamate | Authors: | Ghosh, K, Anumula, R, Kumar, A. | Deposit date: | 2020-09-26 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection. J.Med.Chem., 63, 2020
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5CW5
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![BU of 5cw5 by Molmil](/molmil-images/mine/5cw5) | Structure of CfBRCC36-CfKIAA0157 complex (QSQ mutant) | Descriptor: | BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B | Authors: | Zeqiraj, E. | Deposit date: | 2015-07-27 | Release date: | 2015-09-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.736 Å) | Cite: | Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
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5CW3
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![BU of 5cw3 by Molmil](/molmil-images/mine/5cw3) | Structure of CfBRCC36-CfKIAA0157 complex (Zn Edge) | Descriptor: | BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B, ZINC ION | Authors: | Zeqiraj, E. | Deposit date: | 2015-07-27 | Release date: | 2015-09-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
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2HQ6
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![BU of 2hq6 by Molmil](/molmil-images/mine/2hq6) | Structure of the Cyclophilin_CeCYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 from Homo Sapiens | Descriptor: | GLYCEROL, IODIDE ION, Serologically defined colon cancer antigen 10 | Authors: | Walker, J.R, Davis, T, Paramanathan, R, Newman, E.M, Finerty Jr, P.J, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-07-18 | Release date: | 2006-08-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol., 8, 2010
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2KNB
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![BU of 2knb by Molmil](/molmil-images/mine/2knb) | Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain | Descriptor: | E3 ubiquitin-protein ligase parkin, Endophilin-A1 | Authors: | Trempe, J, Guennadi, K, Edna, C.M, Kalle, G. | Deposit date: | 2009-08-20 | Release date: | 2009-12-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination. Mol.Cell, 36, 2009
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2ZR1
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![BU of 2zr1 by Molmil](/molmil-images/mine/2zr1) | Agglutinin from Abrus Precatorius | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Agglutinin-1 chain A, Agglutinin-1 chain B | Authors: | Cheng, J, Lu, T.H, Liu, C.L, Lin, J.Y. | Deposit date: | 2008-08-22 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A biophysical elucidation for less toxicity of Agglutinin than Abrin-a from the Seeds of Abrus Precatorius in consequence of crystal structure J.Biomed.Sci., 17, 2010
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5T5W
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![BU of 5t5w by Molmil](/molmil-images/mine/5t5w) | Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon lambda receptor 1, Interferon lambda-3, ... | Authors: | Mendoza, J.L, Jude, K.M, Garcia, K.C. | Deposit date: | 2016-08-31 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity, 46, 2017
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2M2S
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![BU of 2m2s by Molmil](/molmil-images/mine/2m2s) | Solution structure of the antimicrobial peptide [Aba5,7,12,14]BTD-2 | Descriptor: | [Aba5,7,12,14]BTD-2 | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | Deposit date: | 2013-01-02 | Release date: | 2013-02-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. J.Biol.Chem., 288, 2013
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2LWV
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![BU of 2lwv by Molmil](/molmil-images/mine/2lwv) | |
2LWT
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![BU of 2lwt by Molmil](/molmil-images/mine/2lwt) | |
2MG9
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![BU of 2mg9 by Molmil](/molmil-images/mine/2mg9) | Truncated EGF-A | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor | Authors: | Schroeder, C.I, Rosengren, K. | Deposit date: | 2013-10-30 | Release date: | 2014-04-02 | Method: | SOLUTION NMR | Cite: | Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro. Chem.Biol., 21, 2014
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2M2H
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![BU of 2m2h by Molmil](/molmil-images/mine/2m2h) | Solution structure of the antimicrobial peptide [Aba3,7,12,16]BTD-2 | Descriptor: | [Aba3,7,12,16]BTD-2 | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | Deposit date: | 2012-12-20 | Release date: | 2013-02-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. J.Biol.Chem., 288, 2013
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2M2G
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![BU of 2m2g by Molmil](/molmil-images/mine/2m2g) | Solution structure of the antimicrobial peptide [Aba3,16]BTD-2 | Descriptor: | [Aba3,16]BTD-2 | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | Deposit date: | 2012-12-20 | Release date: | 2013-02-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. J.Biol.Chem., 288, 2013
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2M2X
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![BU of 2m2x by Molmil](/molmil-images/mine/2m2x) | Solution structure of the antimicrobial peptide [Aba3,5,7,12,14,16]BTD-2 | Descriptor: | [Aba3,5,7,12,14,16]BTD-2 | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | Deposit date: | 2013-01-03 | Release date: | 2013-02-27 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. J.Biol.Chem., 288, 2013
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2M78
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![BU of 2m78 by Molmil](/molmil-images/mine/2m78) | [Asp11]RTD-1 | Descriptor: | [Asp11]RTD-1 | Authors: | Conibear, A.C, Bochen, A, Rosengren, K, Kessler, H, Craik, D.J. | Deposit date: | 2013-04-19 | Release date: | 2014-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Cyclic Cystine Ladder of Theta-Defensins as a Stable, Bifunctional Scaffold: A Proof-of-Concept Study Using the Integrin-Binding RGD Motif Chembiochem, 15, 2014
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