2M2X

Solution structure of the antimicrobial peptide [Aba3,5,7,12,14,16]BTD-2

Summary for 2M2X

• Entry DOI: 10.2210/pdb2m2x/pdb
• Related: 2M1P 2M2G 2M2H 2M2S 2M2Y 2lye
• NMR Information: BMRB: 18937
• Related PRD ID: PRD_001009
• Descriptor: [Aba3,5,7,12,14,16]BTD-2 (1 entity in total)
• Functional Keywords: theta-defensin, cyclic peptides, cyclic cystine ladder, disulfide bond, antimicrobial peptide, antimicrobial protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 1982.43

Authors

Conibear, A.C.,Rosengren, K.,Daly, N.L.,Troiera Henriques, S.,Craik, D.J. (deposition date: 2013-01-03, release date: 2013-02-27, Last modification date: 2023-11-15)

• Primary citation: Conibear, A.C.,Rosengren, K.J.,Daly, N.L.,Henriques, S.T.,Craik, D.J.; The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity.; J.Biol.Chem., 288:10830-10840, 2013; PubMed: 23430740; DOI: 10.1074/jbc.M113.451047

Experimental method

SOLUTION NMR