6IYA
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4FKE
| Crystal structure of porcine aminopeptidase-N | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2012-06-13 | Release date: | 2012-10-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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4FKH
| Crystal structure of porcine aminopeptidase-N complexed with alanine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2012-06-13 | Release date: | 2012-10-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HOM
| Crystal structure of porcine aminopeptidase-N complexed with substance P | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2012-10-22 | Release date: | 2012-10-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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4FKK
| Crystal structure of porcine aminopeptidase-N complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2012-06-13 | Release date: | 2012-10-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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4I9H
| Crystal structure of rabbit LDHA in complex with AP28669 | Descriptor: | 1-O-[3-(5-carboxypyridin-2-yl)-5-fluorophenyl]-6-O-[4-({[(5-carboxypyridin-2-yl)sulfanyl]acetyl}amino)-2-chloro-5-methoxyphenyl]-D-mannitol, L-lactate dehydrogenase A chain | Authors: | Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Shakespeare, W.C, Zhu, X, Dalgarno, D.C. | Deposit date: | 2012-12-05 | Release date: | 2013-01-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. J.Med.Chem., 56, 2013
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4KX8
| Crystal structure of human aminopeptidase A complexed with amastatin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KXB
| Crystal structure of human aminopeptidase A complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX7
| Crystal structure of human aminopeptidase A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KXA
| Crystal structure of human aminopeptidase A complexed with aspartate and calcium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4KX9
| Crystal structure of human aminopeptidase A complexed with arginine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-24 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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3R4D
| Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CEA-related cell adhesion molecule 1, ... | Authors: | Peng, G.Q, Sun, D.W, Rajashankar, K.R, Qian, Z.H, Holmes, K.V, Li, F. | Deposit date: | 2011-03-17 | Release date: | 2011-06-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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4L3N
| Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | Authors: | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | Deposit date: | 2013-06-06 | Release date: | 2013-07-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus. J.Virol., 87, 2013
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4KXC
| Crystal structure of human aminopeptidase A complexed with glutamate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-25 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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4LNP
| The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin | Descriptor: | Sorbin and SH3 domain-containing protein 1, Vinculin | Authors: | Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q. | Deposit date: | 2013-07-11 | Release date: | 2014-05-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
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4LN2
| The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin | Descriptor: | Sorbin and SH3 domain-containing protein 1, proline rich peptide | Authors: | Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q. | Deposit date: | 2013-07-11 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
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4KXD
| Crystal structure of human aminopeptidase A complexed with glutamate and calcium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yang, Y, Liu, C, Lin, Y.Y, Li, F. | Deposit date: | 2013-05-25 | Release date: | 2013-07-31 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into central hypertension regulation by human aminopeptidase a. J.Biol.Chem., 288, 2013
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3SCL
| Crystal structure of spike protein receptor-binding domain from SARS coronavirus epidemic strain complexed with human-civet chimeric receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2 chimera, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
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4NVQ
| Human G9a in Complex with Inhibitor A-366 | Descriptor: | 5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indol]-2'-amine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Sweis, R.F, Pliushchev, M, Brown, P.J, Guo, J, Li, F, Maag, D, Petros, A.M, Soni, N.B, Tse, C, Vedadi, M, Michaelides, M.R, Chiang, G.G, Pappano, W.N. | Deposit date: | 2013-12-05 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Discovery and development of potent and selective inhibitors of histone methyltransferase g9a. ACS Med Chem Lett, 5, 2014
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4NN2
| Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6 | Descriptor: | GLYCEROL, PHD finger protein 6, ZINC ION | Authors: | Liu, Z, Li, F, Zhang, J, Mei, Y, Wu, J, Shi, Y. | Deposit date: | 2013-11-16 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.472 Å) | Cite: | Crystal Structure of the second extended PHD domain of human PHF6 protein J.Biol.Chem., 2014
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3SCI
| Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus human strain complexed with human receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
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4OU3
| Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | Authors: | Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2014-02-14 | Release date: | 2014-11-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy. J.Biol.Chem., 289, 2014
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3SCK
| Crystal structure of spike protein receptor-binding domain from a predicted SARS coronavirus civet strain complexed with human-civet chimeric receptor ACE2 | Descriptor: | Angiotensin-converting enzyme 2 chimera, CHLORIDE ION, Spike glycoprotein, ... | Authors: | Wu, K, Peng, G, Wilken, M, Geraghty, R, Li, F. | Deposit date: | 2011-06-07 | Release date: | 2012-02-08 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus. J.Biol.Chem., 287, 2012
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4NAQ
| Crystal structure of porcine aminopeptidase-N complexed with poly-alanine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2013-10-22 | Release date: | 2013-12-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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4NZ8
| Crystal structure of porcine aminopeptidase-N complexed with cleaved poly-alanine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | Authors: | Chen, L, Lin, Y.L, Peng, G, Li, F. | Deposit date: | 2013-12-11 | Release date: | 2013-12-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
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