2DEI
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![BU of 2dei by Molmil](/molmil-images/mine/2dei) | Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PNP and galactose | Descriptor: | MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, Probable galactokinase, alpha-D-galactopyranose | Authors: | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-02-10 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of galaktokinase from Pyrococcus horikoshii To be Published
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2DSY
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![BU of 2dsy by Molmil](/molmil-images/mine/2dsy) | Crystal structure of TTHA0281 from thermus thermophilus HB8 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hypothetical protein TTHA0281, MAGNESIUM ION | Authors: | Okazaki, N, Kumei, M, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-07-07 | Release date: | 2007-03-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a UPF0150-family protein from Thermus thermophilus HB8 ACTA CRYSTALLOGR.,SECT.F, 63, 2007
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2DEV
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![BU of 2dev by Molmil](/molmil-images/mine/2dev) | Crystal structure of tt0972 protein from Thermus Thermophilus with Cs(+) ions | Descriptor: | CESIUM ION, CHLORIDE ION, SODIUM ION, ... | Authors: | Inagaki, E, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-02-17 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of tt0972 protein from Thermus Thermophilus To be Published
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2DEG
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![BU of 2deg by Molmil](/molmil-images/mine/2deg) | Crystal structure of tt0972 protein form Thermus Thermophilus with Mn2(+) ions | Descriptor: | GLYCEROL, MANGANESE (II) ION, SODIUM ION, ... | Authors: | Inagaki, E, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-02-10 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of tt0972 protein form Thermus Thermophilus To be Published
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2E7X
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![BU of 2e7x by Molmil](/molmil-images/mine/2e7x) | Structure of the Lrp/AsnC like transcriptional regulator from Sulfolobus tokodaii 7 complexed with its cognate ligand | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-15 | Release date: | 2008-01-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EFN
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![BU of 2efn by Molmil](/molmil-images/mine/2efn) | Crystal Structure of Ser 32 to Ala of ST1022 from Sulfolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EH3
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![BU of 2eh3 by Molmil](/molmil-images/mine/2eh3) | Crystal structure of aq_1058, a transcriptional regulator (TerR/AcrR family) from Aquifex aeolicus VF5 | Descriptor: | MAGNESIUM ION, Transcriptional regulator | Authors: | Agari, Y, Shinkai, A, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-03 | Release date: | 2007-09-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of aq_1058, a transcriptional regulator (TerR/AcrR family) from Aquifex aeolicus VF5 To be Published
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2E7W
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![BU of 2e7w by Molmil](/molmil-images/mine/2e7w) | Crystal structure of the Lrp/AsnC like transcriptional regulators from Sulfolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-15 | Release date: | 2008-01-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EFP
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![BU of 2efp by Molmil](/molmil-images/mine/2efp) | Crystal Structure of Tyr77 to Ala of ST1022-Glutamine Complex from Sulolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2E85
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![BU of 2e85 by Molmil](/molmil-images/mine/2e85) | Crystal Structure of the Hydrogenase 3 Maturation protease | Descriptor: | CALCIUM ION, Hydrogenase 3 maturation protease | Authors: | Tanaka, T, Kumarevel, T.S, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-18 | Release date: | 2008-01-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of hydrogenase maturating endopeptidase HycI from Escherichia coli Biochem.Biophys.Res.Commun., 389, 2009
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2EFO
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![BU of 2efo by Molmil](/molmil-images/mine/2efo) | Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EFQ
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![BU of 2efq by Molmil](/molmil-images/mine/2efq) | Crystal Structure of Thr134 to Ala of ST1022-Glutamine Complex from Sulfolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2H0A
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![BU of 2h0a by Molmil](/molmil-images/mine/2h0a) | |
2GZW
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![BU of 2gzw by Molmil](/molmil-images/mine/2gzw) | Crystal structure of the E.coli CRP-cAMP complex | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | Authors: | Kumarevel, T.S, Tanaka, T, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-05-12 | Release date: | 2007-05-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of activated CRP protein from E coli To be Published
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2H9U
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![BU of 2h9u by Molmil](/molmil-images/mine/2h9u) | Crystal structure of the archaea specific DNA binding protein | Descriptor: | 1,2-ETHANEDIOL, DNA/RNA-binding protein Alba 2 | Authors: | Kumarevel, T.S, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-06-12 | Release date: | 2007-06-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the archaea specific DNA binding protein from Aeropyrum pernix K1 To be Published
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2EB7
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![BU of 2eb7 by Molmil](/molmil-images/mine/2eb7) | Crystal structure of the hypothetical regulator from Sulfolobus tokodaii 7 | Descriptor: | 146aa long hypothetical transcriptional regulator | Authors: | Kumarevel, T.S, Nishio, M, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-07 | Release date: | 2007-11-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the MarR family regulatory protein, ST1710, from Sulfolobus tokodaii strain 7 J.Struct.Biol., 161, 2008
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2DEJ
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![BU of 2dej by Molmil](/molmil-images/mine/2dej) | Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose | Descriptor: | Probable galactokinase, alpha-D-galactopyranose, {5'-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM | Authors: | Inagaki, E, Sakamoto, K, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-02-10 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of galaktokinase from Pyrococcus horikoshii To be Published
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2DJW
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![BU of 2djw by Molmil](/molmil-images/mine/2djw) | Crystal structure of TTHA0845 from Thermus thermophilus HB8 | Descriptor: | ZINC ION, probable transcriptional regulator, AsnC family | Authors: | Okazaki, N, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-05 | Release date: | 2006-09-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the stand-alone RAM-domain protein from Thermus thermophilus HB8 ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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5WJJ
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![BU of 5wjj by Molmil](/molmil-images/mine/5wjj) | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors | Descriptor: | Mitogen-activated protein kinase 14, N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide | Authors: | Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C. | Deposit date: | 2017-07-23 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors. Bioorg. Med. Chem., 26, 2018
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6ANL
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![BU of 6anl by Molmil](/molmil-images/mine/6anl) | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors | Descriptor: | Mitogen-activated protein kinase 14, TAK-715 | Authors: | Snell, G.P, Okada, K, Bragstad, K, Sang, B.-C. | Deposit date: | 2017-08-14 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors. Bioorg. Med. Chem., 26, 2018
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6OHD
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![BU of 6ohd by Molmil](/molmil-images/mine/6ohd) | P38 in complex with T-3220137 | Descriptor: | 3-(3-tert-butyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-4-methyl-N-(1,2-oxazol-3-yl)benzamide, Mitogen-activated protein kinase 14 | Authors: | Lane, W, Saikatendu, K. | Deposit date: | 2019-04-05 | Release date: | 2019-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]Pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 2. Chemmedchem, 14, 2019
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7WDC
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![BU of 7wdc by Molmil](/molmil-images/mine/7wdc) | Crystal Structure of Cyanobacterial Circadian Clock Protein KaiC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION | Authors: | Furuike, Y, Akiyama, S. | Deposit date: | 2021-12-21 | Release date: | 2022-07-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Highly sensitive tryptophan fluorescence probe for detecting rhythmic conformational changes of KaiC in the cyanobacterial circadian clock system. Biochem.J., 479, 2022
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6M95
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![BU of 6m95 by Molmil](/molmil-images/mine/6m95) | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping: compound 1 | Descriptor: | (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone, Mitogen-activated protein kinase 14 | Authors: | Lane, W, Okada, K. | Deposit date: | 2018-08-22 | Release date: | 2019-04-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1. Chemmedchem, 14, 2019
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6M9L
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![BU of 6m9l by Molmil](/molmil-images/mine/6m9l) | Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping - compound 10 | Descriptor: | 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, Mitogen-activated protein kinase 14 | Authors: | Lane, W, Okada, K. | Deposit date: | 2018-08-23 | Release date: | 2019-04-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1. Chemmedchem, 14, 2019
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3CT2
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![BU of 3ct2 by Molmil](/molmil-images/mine/3ct2) | Crystal structure of muconate cycloisomerase from Pseudomonas fluorescens | Descriptor: | MAGNESIUM ION, Muconate cycloisomerase | Authors: | Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-04-11 | Release date: | 2008-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes. Biochemistry, 48, 2009
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