7UK9
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![BU of 7uk9 by Molmil](/molmil-images/mine/7uk9) | Integrin alaphIIBbeta3 complex with lamifiban (Mn) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-31 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.60001969 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UFH
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![BU of 7ufh by Molmil](/molmil-images/mine/7ufh) | Integrin alaphIIBbeta3 complex with fradafiban (Mn/Ca) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-22 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.99768162 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKT
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![BU of 7ukt by Molmil](/molmil-images/mine/7ukt) | Integrin alaphIIBbeta3 complex with BMS4.2 | Descriptor: | (1-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperidin-4-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-04-01 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.36994433 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UCY
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![BU of 7ucy by Molmil](/molmil-images/mine/7ucy) | Integrin alaphIIBbeta3 complex with gantofiban | Descriptor: | (4-{[(5R)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-17 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.34996319 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKO
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![BU of 7uko by Molmil](/molmil-images/mine/7uko) | Integrin alaphIIBbeta3 complex with sibrafiban (Mn) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-04-01 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UJK
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![BU of 7ujk by Molmil](/molmil-images/mine/7ujk) | Integrin alaphIIBbeta3 complex with lamifiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.43265581 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UDG
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![BU of 7udg by Molmil](/molmil-images/mine/7udg) | Integrin alaphIIBbeta3 complex with lotrafiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-19 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.800069 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UE0
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![BU of 7ue0 by Molmil](/molmil-images/mine/7ue0) | Integrin alaphIIBbeta3 complex with fradafiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-20 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.741962 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UJE
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![BU of 7uje by Molmil](/molmil-images/mine/7uje) | Integrin alaphIIBbeta3 complex with UR2922 in Mn2+ | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.499968 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKP
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![BU of 7ukp by Molmil](/molmil-images/mine/7ukp) | Integrin alaphIIBbeta3 complex with a gantofiban analog | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-04-01 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.80112982 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UBR
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![BU of 7ubr by Molmil](/molmil-images/mine/7ubr) | Integrin alaphIIBbeta3 complex with GR144053 | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-15 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.04992747 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UH8
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![BU of 7uh8 by Molmil](/molmil-images/mine/7uh8) | Integrin alaphIIBbeta3 complex with roxifiban (Mn/Ca) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-25 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.750024 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7U9F
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![BU of 7u9f by Molmil](/molmil-images/mine/7u9f) | Integrin alaphIIBbeta3 complex with BMS compound 4 in Mn2+ | Descriptor: | (4-{[(5S)-3-{4-[(E)-imino(4-methylpiperazin-1-yl)methyl]phenyl}-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-10 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.70000529 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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8EQN
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![BU of 8eqn by Molmil](/molmil-images/mine/8eqn) | |
5EGG
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![BU of 5egg by Molmil](/molmil-images/mine/5egg) | |
5GNV
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![BU of 5gnv by Molmil](/molmil-images/mine/5gnv) | Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain | Descriptor: | Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION | Authors: | Shang, Y, Xia, Y, Zhu, R, Zhu, J. | Deposit date: | 2016-07-25 | Release date: | 2017-08-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain Biochem. J., 474, 2017
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4JTS
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![BU of 4jts by Molmil](/molmil-images/mine/4jts) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072 | Descriptor: | 4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 To be Published
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4JTU
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![BU of 4jtu by Molmil](/molmil-images/mine/4jtu) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with brequinar analogue | Descriptor: | 6-bromo-2-{4-[(2R)-butan-2-yl]phenyl}-3-methylquinoline-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 To be Published
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4JS3
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![BU of 4js3 by Molmil](/molmil-images/mine/4js3) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 | Descriptor: | 2-chloro-4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETIC ACID, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Zhu, J, Ren, X. | Deposit date: | 2013-03-22 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 TO BE PUBLISHED
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4JGD
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![BU of 4jgd by Molmil](/molmil-images/mine/4jgd) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016 | Descriptor: | 1-[4-methyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]ethanone, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-01 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016 TO BE PUBLISHED
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4JTT
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![BU of 4jtt by Molmil](/molmil-images/mine/4jtt) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 066 | Descriptor: | 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Zhu, J, Ren, X. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 TO BE PUBLISHED
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4LS0
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![BU of 4ls0 by Molmil](/molmil-images/mine/4ls0) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033 | Descriptor: | 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzaldehyde, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Li, H, Ren, X, Zhu, J. | Deposit date: | 2013-07-21 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033 To be Published
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4LS2
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![BU of 4ls2 by Molmil](/molmil-images/mine/4ls2) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313 | Descriptor: | 2-[(E)-{2-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Ren, X, Zhu, J. | Deposit date: | 2013-07-21 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313 To be Published
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4G5S
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![BU of 4g5s by Molmil](/molmil-images/mine/4g5s) | Structure of LGN GL3/Galphai3 complex | Descriptor: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | Deposit date: | 2012-07-18 | Release date: | 2012-09-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins To be Published
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7U08
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![BU of 7u08 by Molmil](/molmil-images/mine/7u08) | |