5UOC
| Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(2S)-2-(methylamino)propyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | Authors: | Chreifi, G, Li, H, Poulos, T.L. | Deposit date: | 2017-01-31 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
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5UR9
| Enantiomer-Specific Binding of the Potent Antinociceptive Agent SBFI-26 to Anandamide transporters FABP5 | Descriptor: | (1S,2S,3S,4S)-3-{[(naphthalen-1-yl)oxy]carbonyl}-2,4-diphenylcyclobutane-1-carboxylic acid, Fatty acid-binding protein, epidermal, ... | Authors: | Hsu, H.-C, Li, H. | Deposit date: | 2017-02-09 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.19800353 Å) | Cite: | The Antinociceptive Agent SBFI-26 Binds to Anandamide Transporters FABP5 and FABP7 at Two Different Sites. Biochemistry, 56, 2017
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7TFL
| Atomic model of S. cerevisiae clamp loader RFC bound to DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2022-01-06 | Release date: | 2022-11-16 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Elife, 11, 2022
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3Q6F
| Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | Descriptor: | DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909 | Authors: | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | Deposit date: | 2010-12-31 | Release date: | 2011-05-25 | Last modified: | 2011-10-12 | Method: | X-RAY DIFFRACTION (3.192 Å) | Cite: | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120. Structure, 19, 2011
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3RIV
| The Crystal Structure of Leishmania major Peroxidase | Descriptor: | Ascorbate peroxidase, CALCIUM ION, POTASSIUM ION, ... | Authors: | Jasion, V.S, Li, H, Poulos, T.L. | Deposit date: | 2011-04-14 | Release date: | 2011-05-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structure of Leishmania major Peroxidase and Characterization of the Compound I Tryptophan Radical. J.Biol.Chem., 286, 2011
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3RNR
| Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, GLYCEROL, ... | Authors: | Kim, Y, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-22 | Release date: | 2011-06-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans To be Published
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1WJI
| Solution Structure of the UBA Domain of Human Tudor Domain Containing Protein 3 | Descriptor: | Tudor domain containing protein 3 | Authors: | Kamatari, Y.O, Tochio, N, Nakanishi, T, Miyamoto, K, Li, H, Kobayashi, N, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-29 | Release date: | 2004-11-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of the UBA Domain of Human Tudor Domain Containing Protein 3 To be Published
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5UO9
| Structure of human endothelial nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 7-({3-ethyl-5-[(methylamino)methyl]phenoxy}methyl)quinolin-2-amine, ... | Authors: | Chreifi, G, Li, H, Poulos, T.L. | Deposit date: | 2017-01-31 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
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5UQP
| The crystal structure of cupin protein from Rhodococcus jostii RHA1 | Descriptor: | CHLORIDE ION, Cupin, SULFATE ION, ... | Authors: | Tan, K, Li, H, Clancy, S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2017-02-08 | Release date: | 2017-02-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of cupin protein from Rhodococcus jostii RHA1 To Be Published
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5TGN
| Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus | Descriptor: | CHLORIDE ION, GLYCEROL, Uncharacterized protein | Authors: | Michalska, K, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2016-09-28 | Release date: | 2016-10-26 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal structure of protein Sthe_2403 from Sphaerobacter thermophilus To Be Published
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1RLG
| Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex | Descriptor: | 25-MER, 50S ribosomal protein L7Ae | Authors: | Moore, T, Zhang, Y, Fenley, M.O, Li, H. | Deposit date: | 2003-11-25 | Release date: | 2004-06-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA. STRUCTURE, 12, 2004
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5UO8
| Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(2-aminoquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | Authors: | Chreifi, G, Li, H, Poulos, T.L. | Deposit date: | 2017-01-31 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. J. Med. Chem., 60, 2017
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4KCP
| Structure of bovine endotheial nitric oxide synthase heme domain in complex with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ... | Authors: | Chreifi, G, Li, H, Poulos, T.L. | Deposit date: | 2013-04-24 | Release date: | 2014-02-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma. J.Med.Chem., 57, 2014
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3RPD
| The structure of a B12-independent methionine synthase from Shewanella sp. W3-18-1 in complex with Selenomethionine. | Descriptor: | GLYCEROL, Methionine synthase (B12-independent), SELENOMETHIONINE, ... | Authors: | Cuff, M.E, Li, H, Hatzos-Skintges, C, Tesar, C, Bearden, J, Clancy, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-26 | Release date: | 2011-08-31 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of a B12-independent methionine synthase from Shewanella sp. W3-18-1 in complex with Selenomethionine. TO BE PUBLISHED
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6BS8
| The class 3 DnaB intein from Mycobacterium smegmatis | Descriptor: | Replicative DNA helicase | Authors: | Li, Z, Kelley, D.S, Banavali, N, Belfort, M, Li, H. | Deposit date: | 2017-12-01 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mycobacterial DnaB helicase intein as oxidative stress sensor. Nat Commun, 9, 2018
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3PN8
| The crystal structure of 6-phospho-beta-glucosidase from Streptococcus mutans UA159 | Descriptor: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, Putative phospho-beta-glucosidase, ... | Authors: | Tan, K, Li, H, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-11-18 | Release date: | 2010-12-15 | Last modified: | 2012-08-08 | Method: | X-RAY DIFFRACTION (1.693 Å) | Cite: | The crystal structure of 6-phospho-beta-glucosidase from Streptococcus mutants UA159 To be Published
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1PKH
| STRUCTURAL BASIS FOR RECOGNITION AND CATALYSIS BY THE BIFUNCTIONAL DCTP DEAMINASE AND DUTPASE FROM METHANOCOCCUS JANNASCHII | Descriptor: | 1,2-ETHANEDIOL, Bifunctional deaminase/diphosphatase | Authors: | Huffman, J.L, Li, H, White, R.H, Tainer, J.A. | Deposit date: | 2003-06-05 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii J.Mol.Biol., 331, 2003
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1Q1W
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3ROB
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3RL7
| Crystal structure of hDLG1-PDZ1 complexed with APC | Descriptor: | 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1 | Authors: | Zhang, Z, Li, H, Wu, G. | Deposit date: | 2011-04-19 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein. Plos One, 6, 2011
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1TVK
| The binding mode of epothilone A on a,b-tubulin by electron crystallography | Descriptor: | EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Nettles, J.H, Li, H, Cornett, B, Krahn, J.M, Snyder, J.P, Downing, K.H. | Deposit date: | 2004-06-29 | Release date: | 2004-09-14 | Last modified: | 2023-08-23 | Method: | ELECTRON CRYSTALLOGRAPHY (2.89 Å) | Cite: | The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography Science, 305, 2004
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3R0A
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1S4K
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1PKJ
| Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii | Descriptor: | 1,2-ETHANEDIOL, Bifunctional deaminase/diphosphatase, DEOXYURIDINE-5'-TRIPHOSPHATE | Authors: | Huffman, J.L, Li, H, White, R.H, Tainer, J.A. | Deposit date: | 2003-06-05 | Release date: | 2003-09-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii J.Mol.Biol., 331, 2003
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5VUG
| Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase Domain of Uncharacterized Protein Rv2277c from Mycobacterium tuberculosis | Descriptor: | CALCIUM ION, GLYCEROL, Uncharacterized protein Rv2277c | Authors: | Kim, Y, Li, H, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-05-19 | Release date: | 2017-06-14 | Last modified: | 2017-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of Glycerophosphoryl Diester Phosphodiesterase Domain of Uncharacterized Protein Rv2277c from Mycobacterium tuberculosis To Be Published
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