3CFN
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3CFQ
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3G9V
| Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 | Descriptor: | Interleukin 22 receptor, alpha 2, Interleukin-22 | Authors: | de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I. | Deposit date: | 2009-02-14 | Release date: | 2009-04-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.756 Å) | Cite: | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 FEBS Lett., 583, 2009
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3EXD
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1B8E
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1DN0
| STRUCTURE OF THE FAB FRAGMENT FROM A HUMAN IGM COLD AGGLUTININ | Descriptor: | IGM-KAPPA COLD AGGLUTININ (HEAVY CHAIN), IGM-KAPPA COLD AGGLUTININ (LIGHT CHAIN) | Authors: | Cauerhff, A, Braden, B, Carvalho, J.G, Leoni, J, Polikarpov, I, Goldbaum, F. | Deposit date: | 1999-12-15 | Release date: | 2001-01-24 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Three-dimensional structure of the Fab from a human IgM cold agglutinin. J.Immunol., 165, 2000
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3GWS
| Crystal Structure of T3-Bound Thyroid Hormone Receptor | Descriptor: | 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor beta | Authors: | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Polikarpov, I, Baxter, J.D, Webb, P. | Deposit date: | 2009-04-01 | Release date: | 2009-04-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function J.Mol.Biol., 360, 2006
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3HDL
| Crystal Structure of Highly Glycosylated Peroxidase from Royal Palm Tree | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Watanabe, L, Moura, P.R, Bleicher, L, Nascimento, A.S, Zamorano, L.S, Calvete, J.J, Bursakov, S, Roig, M.G, Shnyrov, V.L, Polikarpov, I. | Deposit date: | 2009-05-07 | Release date: | 2009-11-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia). J.Struct.Biol., 169, 2010
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3ILN
| X-ray structure of the laminarinase from Rhodothermus marinus | Descriptor: | CALCIUM ION, GLYCEROL, Laminarinase | Authors: | Bleicher, L, Golubev, A, Rojas, A.L, Nascimento, A.S, Polikarpov, I. | Deposit date: | 2009-08-07 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations. J.Phys.Chem.B, 115, 2011
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3HZF
| Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group | Descriptor: | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | Authors: | Aparicio, R, Bleicher, L, Polikarpov, I. | Deposit date: | 2009-06-23 | Release date: | 2009-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8, 2008
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1QFE
| THE STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE FROM SALMONELLA TYPHI | Descriptor: | 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, PROTEIN (3-DEHYDROQUINATE DEHYDRATASE) | Authors: | Shrive, A.K, Polikarpov, I, Sawyer, L, Coggins, J.R, Hawkins, A.R. | Deposit date: | 1999-04-05 | Release date: | 2000-04-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction. Nat.Struct.Biol., 6, 1999
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1QG5
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3I36
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1QLL
| Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai | Descriptor: | N-TRIDECANOIC ACID, PHOSPHOLIPASE A2 | Authors: | Lee, W.-H, Polikarpov, I. | Deposit date: | 1999-09-01 | Release date: | 2000-09-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid Biochemistry, 40, 2001
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3KGU
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4CI5
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4DES
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4BCR
| Structure of PPARalpha in complex with WY14643 | Descriptor: | 1,2-ETHANEDIOL, 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA | Authors: | Bernardes, A, Muniz, J.R.C, Polikarpov, I. | Deposit date: | 2012-10-02 | Release date: | 2013-05-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Molecular Mechanism of Peroxisome Proliferator-Activated Receptor Alpha Activation by Wy14643: A New Mode of Ligand Recognition and Receptor Stabilization J.Mol.Biol., 425, 2013
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4DET
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4DER
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4DEW
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4EMA
| Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone | Descriptor: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma | Authors: | Liberato, M.V, Nascimento, A.S, Polikarpov, I. | Deposit date: | 2012-04-11 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists Plos One, 7, 2012
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4EM9
| Human PPAR gamma in complex with nonanoic acids | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma, ... | Authors: | Liberato, M.V, Nascimento, A.S, Polikarpov, I. | Deposit date: | 2012-04-11 | Release date: | 2013-03-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists Plos One, 7, 2012
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4CI4
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4CVU
| Structure of Fungal beta-mannosidase from Glycoside Hydrolase Family 2 of Trichoderma harzianum | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-MANNOSIDASE, CADMIUM ION, ... | Authors: | Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I. | Deposit date: | 2014-03-31 | Release date: | 2014-07-09 | Last modified: | 2023-07-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into the structure and function of fungal beta-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme. FEBS J., 281, 2014
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