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Structure of substrate engaged MIDN-bound human 26S proteasome, EB-MIDN (Composite map)
Descriptor:	26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, ...
Authors:	Peddada, N, Beutler, B.
Deposit date:	2025-02-28
Release date:	2025-05-07
Last modified:	2025-05-21
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Structural insights into the ubiquitin-independent midnolin-proteasome pathway. Proc.Natl.Acad.Sci.USA, 122, 2025

9NKI

Structure of substrate engaged MIDN-bound human 26S proteasome, EB MIDN_UBL state (Composite map)
Descriptor:	26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, ...
Authors:	Peddada, N, Beutler, B.
Deposit date:	2025-02-28
Release date:	2025-05-07
Last modified:	2025-05-21
Method:	ELECTRON MICROSCOPY (2.94 Å)
Cite:	Structural insights into the ubiquitin-independent midnolin-proteasome pathway. Proc.Natl.Acad.Sci.USA, 122, 2025

9NKJ

Structure of substrates-engaged MIDN-bound human 26S proteasome,ED-MIDN state (Composite map)
Descriptor:	26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, ...
Authors:	Peddada, N, Beutler, B.
Deposit date:	2025-02-28
Release date:	2025-05-07
Last modified:	2025-05-21
Method:	ELECTRON MICROSCOPY (3.84 Å)
Cite:	Structural insights into the ubiquitin-independent midnolin-proteasome pathway. Proc.Natl.Acad.Sci.USA, 122, 2025

8H10

Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-2 Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-10-19
Last modified:	2024-11-20
Method:	ELECTRON MICROSCOPY (2.99 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H14

Structure of SARS-CoV-1 Spike Protein with Engineered x3 Disulfide (D414C and V969C), Locked-1 Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-10-19
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.39 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H13

Structure of SARS-CoV-1 Spike Protein with Engineered x2 Disulfide (G400C and V969C), Closed Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-10-19
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (4.05 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H11

Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Closed Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-11-06
Method:	ELECTRON MICROSCOPY (2.72 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H16

Structure of SARS-CoV-1 Spike Protein (S/native) at pH 5.5, Open Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-10-23
Method:	ELECTRON MICROSCOPY (3.35534 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H12

Structure of SARS-CoV-1 Spike Protein with Engineered x2 Disulfide (G400C and V969C), Locked-2 Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (3.44681 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H0Y

Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-112 Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, LINOLEIC ACID, ...
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-11-06
Method:	ELECTRON MICROSCOPY (2.85 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H15

Structure of SARS-CoV-1 Spike Protein (S/native) at pH 5.5, Closed Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-11-20
Method:	ELECTRON MICROSCOPY (3.14182 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

8H0X

Structure of SARS-CoV-1 Spike Protein with Engineered x1 Disulfide (S370C and D967C), Locked-1 Conformation
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, LINOLEIC ACID, ...
Authors:	Zhang, X, Li, Z, Liu, Y, Wang, J, Fu, L, Wang, P, He, J, Xiong, X.
Deposit date:	2022-09-30
Release date:	2022-11-09
Last modified:	2024-11-13
Method:	ELECTRON MICROSCOPY (2.57 Å)
Cite:	Disulfide stabilization reveals conserved dynamic features between SARS-CoV-1 and SARS-CoV-2 spikes. Life Sci Alliance, 6, 2023

4NJ5

Crystal structure of SUVH9
Descriptor:	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH9, ZINC ION
Authors:	Du, J, Patel, D.J.
Deposit date:	2013-11-08
Release date:	2014-01-22
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature, 507, 2014

4E3C

X-ray crystal structure of human IKK2 in an active conformation
Descriptor:	Inhibitor of nuclear factor kappa-B kinase subunit beta
Authors:	Polley, S, Huang, D.B, Hauenstein, A.V, Ghosh, G, Huxford, T.
Deposit date:	2012-03-09
Release date:	2013-06-19
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.98 Å)
Cite:	X-ray crystal structure of human IKK2 in an active conformation Plos.Biol., 2013

4FSX

crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH
Descriptor:	DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:	Du, J, Patel, D.J.
Deposit date:	2012-06-27
Release date:	2012-10-17
Last modified:	2024-11-27
Method:	X-RAY DIFFRACTION (3.2 Å)
Cite:	Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012

4FT4

crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH
Descriptor:	DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE
Authors:	Du, J, Patel, D.J.
Deposit date:	2012-06-27
Release date:	2012-10-17
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012

5V5V

Complex of NLGN2 with MDGA1 Ig1-Ig2
Descriptor:	MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Neuroligin-2
Authors:	Gangwar, S.P, Machius, M, Rudenko, G.
Deposit date:	2017-03-15
Release date:	2017-07-05
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (4.11 Å)
Cite:	Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges. Neuron, 94, 2017

5V5W

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges
Descriptor:	MAM domain-containing glycosylphosphatidylinositol anchor protein 1, SULFATE ION
Authors:	Machius, M, Gangwar, S.P, Rudenko, G.
Deposit date:	2017-03-15
Release date:	2017-07-05
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2.718 Å)
Cite:	Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges. Neuron, 94, 2017

5VIF

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
Descriptor:	2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
Authors:	Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H.
Deposit date:	2017-04-15
Release date:	2017-10-18
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nat. Chem. Biol., 13, 2017

6KN1

P20/P12 of caspase-11 mutant C254A
Descriptor:	Caspase-4
Authors:	Ding, J, Sun, Q.
Deposit date:	2019-08-02
Release date:	2020-03-11
Last modified:	2025-03-12
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020

6KN0

caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
Descriptor:	Caspase-1, Gasdermin-D
Authors:	Ding, J, Sun, Q.
Deposit date:	2019-08-02
Release date:	2020-03-11
Last modified:	2025-03-12
Method:	X-RAY DIFFRACTION (2.793 Å)
Cite:	Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020

5VIE

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
Descriptor:	2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, 2-{[(2E)-but-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, ...
Authors:	Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H.
Deposit date:	2017-04-15
Release date:	2017-10-18
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nat. Chem. Biol., 13, 2017

6KMV

caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
Descriptor:	Caspase-4, Gasdermin-D
Authors:	Ding, J, Sun, Q.
Deposit date:	2019-08-01
Release date:	2020-03-11
Last modified:	2025-03-12
Method:	X-RAY DIFFRACTION (3.35 Å)
Cite:	Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020

6KMZ

caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
Descriptor:	Caspase-4, Gasdermin-D
Authors:	Ding, J, Sun, Q.
Deposit date:	2019-08-01
Release date:	2020-03-11
Last modified:	2025-03-12
Method:	X-RAY DIFFRACTION (3.61 Å)
Cite:	Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020

6KMT

P32 of caspase-11 mutant C254A
Descriptor:	Caspase-4
Authors:	Ding, J, Sun, Q.
Deposit date:	2019-08-01
Release date:	2020-03-11
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180, 2020

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Displayed results:	25
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