4K87
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![BU of 4k87 by Molmil](/molmil-images/mine/4k87) | Crystal structure of human prolyl-tRNA synthetase (substrate bound form) | Descriptor: | ADENOSINE, PROLINE, Proline--tRNA ligase, ... | Authors: | Hwang, K.Y, Son, J.H, Lee, E.H. | Deposit date: | 2013-04-18 | Release date: | 2013-10-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. Acta Crystallogr.,Sect.D, 69, 2013
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4K88
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![BU of 4k88 by Molmil](/molmil-images/mine/4k88) | Crystal structure of human prolyl-tRNA synthetase (halofuginone bound form) | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Proline--tRNA ligase, ZINC ION | Authors: | Hwang, K.Y, Son, J.H, Lee, E.H. | Deposit date: | 2013-04-18 | Release date: | 2013-10-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.619 Å) | Cite: | Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. Acta Crystallogr.,Sect.D, 69, 2013
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2GWO
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![BU of 2gwo by Molmil](/molmil-images/mine/2gwo) | crystal structure of TMDP | Descriptor: | Dual specificity protein phosphatase 13 | Authors: | Kim, S.J, Ryu, S.E, Kim, J.H. | Deposit date: | 2006-05-05 | Release date: | 2007-03-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity Proteins, 66, 2007
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2ESB
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![BU of 2esb by Molmil](/molmil-images/mine/2esb) | Crystal structure of human DUSP18 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Dual specificity protein phosphatase 18 | Authors: | Kim, S.J, Ryu, S.E, Jeong, D.G, Cho, Y.H, Yoon, T.S, Kim, J.H. | Deposit date: | 2005-10-25 | Release date: | 2006-06-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family. Acta Crystallogr.,Sect.D, 62, 2006
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5J4G
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![BU of 5j4g by Molmil](/molmil-images/mine/5j4g) | Crystal structure of the C-terminally His6-tagged HP0902, an uncharacterized protein from Helicobacter pylori 26695 | Descriptor: | Uncharacterized protein | Authors: | Sim, D.W, Lee, W.C, Kim, H.Y, Kim, J.H, Won, H.S. | Deposit date: | 2016-04-01 | Release date: | 2017-02-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural identification of the lipopolysaccharide-binding capability of a cupin-family protein from Helicobacter pylori FEBS Lett., 590, 2016
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5IZV
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![BU of 5izv by Molmil](/molmil-images/mine/5izv) | Crystal structure of the legionella pneumophila effector protein RavZ - F222 | Descriptor: | Uncharacterized protein RavZ | Authors: | Kwon, D.H, Kim, L, Kim, B.-W, Hong, S.B, Song, H.K. | Deposit date: | 2016-03-26 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.814 Å) | Cite: | The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane Autophagy, 13, 2017
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7XZ0
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![BU of 7xz0 by Molmil](/molmil-images/mine/7xz0) | TRIM E3 ubiquitin ligase | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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7XV2
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![BU of 7xv2 by Molmil](/molmil-images/mine/7xv2) | TRIM E3 ubiquitin ligase | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-05-20 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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7XYZ
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![BU of 7xyz by Molmil](/molmil-images/mine/7xyz) | TRIM E3 ubiquitin ligase | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.62 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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7XZ2
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![BU of 7xz2 by Molmil](/molmil-images/mine/7xz2) | TRIM E3 ubiquitin ligase | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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7XYY
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![BU of 7xyy by Molmil](/molmil-images/mine/7xyy) | TRIM E3 ubiquitin ligase WT | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (7.1 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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7XZ1
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![BU of 7xz1 by Molmil](/molmil-images/mine/7xz1) | TRIM E3 ubiquitin ligase | Descriptor: | Tripartite motif-containing protein 72, ZINC ION | Authors: | Park, S.H, Song, H.K. | Deposit date: | 2022-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (5.2 Å) | Cite: | Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane. Nat.Struct.Mol.Biol., 30, 2023
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4RCP
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![BU of 4rcp by Molmil](/molmil-images/mine/4rcp) | Crystal structure of Plk1 Polo-box domain in complex with PL-2 | Descriptor: | 1,2-ETHANEDIOL, PL-2, Serine/threonine-protein kinase PLK1 | Authors: | Lee, W.C, Song, J.H, Kim, H.Y. | Deposit date: | 2014-09-16 | Release date: | 2014-11-12 | Last modified: | 2015-01-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A new class of peptidomimetics targeting the polo-box domain of polo-like kinase 1. J.Med.Chem., 58, 2015
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4KJT
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![BU of 4kjt by Molmil](/molmil-images/mine/4kjt) | Structure of the L100F MUTANT OF DEHALOPEROXIDASE-HEMOGLOBIN A FROM AMPHITRITE ORNATA WITH OXYGEN | Descriptor: | 1,2-ETHANEDIOL, Dehaloperoxidase A, OXYGEN MOLECULE, ... | Authors: | Wang, C, Lovelace, L, Lebioda, L. | Deposit date: | 2013-05-03 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Influence of heme environment structure on dioxygen affinity for the dual function Amphitrite ornata hemoglobin/dehaloperoxidase. Insights into the evolutional structure-function adaptations. Arch.Biochem.Biophys., 545, 2014
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5HZY
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![BU of 5hzy by Molmil](/molmil-images/mine/5hzy) | Crystal structure of the legionella pneumophila effector protein RavZ - P6322 | Descriptor: | Uncharacterized protein RavZ | Authors: | Kwon, D.H, Kim, L, Kim, B.-W, Hong, S.B, Song, H.K. | Deposit date: | 2016-02-03 | Release date: | 2016-11-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.548 Å) | Cite: | The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane Autophagy, 13, 2017
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1BC2
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![BU of 1bc2 by Molmil](/molmil-images/mine/1bc2) | ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS | Descriptor: | METALLO-BETA-LACTAMASE II, SULFATE ION, ZINC ION | Authors: | Fabiane, S.M, Sutton, B.J. | Deposit date: | 1997-04-11 | Release date: | 1998-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 A resolution: binuclear active site with features of a mononuclear enzyme. Biochemistry, 37, 1998
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3CJF
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![BU of 3cjf by Molmil](/molmil-images/mine/3cjf) | Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine | Descriptor: | N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine, SULFATE ION, Vascular endothelial growth factor receptor 2 | Authors: | Nolte, R.T. | Deposit date: | 2008-03-12 | Release date: | 2008-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J.Med.Chem., 51, 2008
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3SLJ
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![BU of 3slj by Molmil](/molmil-images/mine/3slj) | Pre-cleavage Structure of the Autotransporter EspP - N1023A mutant | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP | Authors: | Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K. | Deposit date: | 2011-06-24 | Release date: | 2011-11-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.481 Å) | Cite: | Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter. J.Mol.Biol., 415, 2012
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4KN3
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![BU of 4kn3 by Molmil](/molmil-images/mine/4kn3) | Structure of the Y34NS91G double mutant of Dehaloperoxidase from Amphitrite ornata with 2,4,6-trichlorophenol | Descriptor: | 2,4,6-trichlorophenol, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Wang, C, Lovelace, L, Lebioda, L. | Deposit date: | 2013-05-08 | Release date: | 2013-09-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Complexes of dual-function hemoglobin/dehaloperoxidase with substrate 2,4,6-trichlorophenol are inhibitory and indicate binding of halophenol to compound I. Biochemistry, 52, 2013
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3SLT
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![BU of 3slt by Molmil](/molmil-images/mine/3slt) | Pre-cleavage Structure of the Autotransporter EspP - N1023S Mutant | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP | Authors: | Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K. | Deposit date: | 2011-06-25 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter. J.Mol.Biol., 415, 2012
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3CJG
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![BU of 3cjg by Molmil](/molmil-images/mine/3cjg) | Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine | Descriptor: | N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine, SULFATE ION, Vascular endothelial growth factor receptor 2 | Authors: | Nolte, R.T. | Deposit date: | 2008-03-12 | Release date: | 2008-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J.Med.Chem., 51, 2008
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3SLO
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![BU of 3slo by Molmil](/molmil-images/mine/3slo) | Pre-cleavage Structure of the Autotransporter EspP - N1023D mutant | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Serine protease espP | Authors: | Barnard, T.B, Noinaj, N, Easley, N.C, Kuszak, A.J, Buchanan, S.K. | Deposit date: | 2011-06-24 | Release date: | 2011-11-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter. J.Mol.Biol., 415, 2012
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3SDN
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![BU of 3sdn by Molmil](/molmil-images/mine/3sdn) | Structure of G65I sperm whale myoglobin mutant | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Myoglobin, ... | Authors: | Lebioda, L, Huang, X. | Deposit date: | 2011-06-09 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Amphitrite ornata Dehaloperoxidase (DHP): Investigations of Structural Factors That Influence the Mechanism of Halophenol Dehalogenation Using "Peroxidase-like" Myoglobin Mutants and "Myoglobin-like" DHP Mutants. Biochemistry, 50, 2011
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4KMW
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![BU of 4kmw by Molmil](/molmil-images/mine/4kmw) | Structure of the Y34N MUTANT OF DEHALOPEROXIDASE-HEMOGLOBIN A FROM AMPHITRITE ORNATA WITH 2,4,6-TRICHLOROPHENOL | Descriptor: | 2,4,6-trichlorophenol, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Wang, C, Lovelace, L, Lebioda, L. | Deposit date: | 2013-05-08 | Release date: | 2013-09-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Complexes of dual-function hemoglobin/dehaloperoxidase with substrate 2,4,6-trichlorophenol are inhibitory and indicate binding of halophenol to compound I. Biochemistry, 52, 2013
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3U3E
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![BU of 3u3e by Molmil](/molmil-images/mine/3u3e) | |