Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1Z0N
DownloadVisualize
BU of 1z0n by Molmil
the glycogen-binding domain of the AMP-activated protein kinase
Descriptor: 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose)
Authors:Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W.
Deposit date:2005-03-02
Release date:2005-10-25
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase.
Structure, 13, 2005
1KOA
DownloadVisualize
BU of 1koa by Molmil
TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS
Descriptor: TWITCHIN
Authors:Kobe, B, Heierhorst, J, Feil, S.C, Parker, M.W, Benian, G.M, Weiss, K.R, Kemp, B.E.
Deposit date:1996-06-28
Release date:1997-03-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
1KOB
DownloadVisualize
BU of 1kob by Molmil
TWITCHIN KINASE FRAGMENT (APLYSIA), AUTOREGULATED PROTEIN KINASE DOMAIN
Descriptor: TWITCHIN, VALINE
Authors:Kobe, B, Heierhorst, J, Feil, S.C, Parker, M.W, Benian, G.M, Weiss, K.R, Kemp, B.E.
Deposit date:1996-06-28
Release date:1997-03-12
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Giant protein kinases: domain interactions and structural basis of autoregulation.
EMBO J., 15, 1996
20GS
DownloadVisualize
BU of 20gs by Molmil
GLUTATHIONE S-TRANSFERASE P1-1 COMPLEXED WITH CIBACRON BLUE
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CIBACRON BLUE, GLUTATHIONE S-TRANSFERASE
Authors:Oakley, A.J, Lo Bello, M, Nuccetelli, M, Mazzetti, A.P, Parker, M.W.
Deposit date:1997-12-16
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site).
J.Mol.Biol., 291, 1999
5DAL
DownloadVisualize
BU of 5dal by Molmil
Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the presence of Glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Di-glutathione-PhenylArsine, GLUTATHIONE, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DDL
DownloadVisualize
BU of 5ddl by Molmil
Crystal Structure of WT Human Glutathione Transferase Pi soaked with a metalloid then back-soaked with glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Di-glutathione-PhenylArsine, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-25
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DAK
DownloadVisualize
BU of 5dak by Molmil
Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ARSENIC, Glutathione S-transferase P
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-20
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
5DCG
DownloadVisualize
BU of 5dcg by Molmil
Crystal Structure of WT Apo Human Glutathione Transferase Pi
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glutathione S-transferase P, ...
Authors:Parker, L.J, Parker, M.W, Morton, C.J.
Deposit date:2015-08-24
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Visualisation of Organoarsenic Human Glutathione Transferase P1-1 Complexes: Metabolism of Arsenic-based Therapeutics
To Be Published
3GSS
DownloadVisualize
BU of 3gss by Molmil
HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE, ...
Authors:Oakley, A.J, Rossjohn, J, Parker, M.W.
Deposit date:1996-10-29
Release date:1997-11-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate.
Biochemistry, 36, 1997
6NMY
DownloadVisualize
BU of 6nmy by Molmil
A Cytokine-receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, ...
Authors:Dhagat, U, Kan, W.L, Hercus, T.R, Broughton, S.E, Nero, T.L, Lopez, A.F, Parker, M.W.
Deposit date:2019-01-13
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Signalling conformation of cell surface receptor
To Be Published
8E17
DownloadVisualize
BU of 8e17 by Molmil
BRD4-D1 in complex with BET inhibitor
Descriptor: (4P,6M)-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-4-[5-(methanesulfonyl)-2-methoxyphenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
Authors:Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
Deposit date:2022-08-09
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
8DYR
DownloadVisualize
BU of 8dyr by Molmil
BRD4-D1 in complex with BET inhibitor
Descriptor: (4P,6P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
Authors:Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
Deposit date:2022-08-04
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
8E3W
DownloadVisualize
BU of 8e3w by Molmil
BRD4-D1 in complex with BET inhibitor
Descriptor: (4P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
Authors:Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
Deposit date:2022-08-17
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
6NAL
DownloadVisualize
BU of 6nal by Molmil
Crystal Structure of Gram Negative Toxin
Descriptor: IMIDAZOLE, TETRAETHYLENE GLYCOL, Thiol-activated cytolysin
Authors:Morton, C.J, Lawrence, S.A, Parker, M.W.
Deposit date:2018-12-05
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin.
Mbio, 10, 2019
6OIR
DownloadVisualize
BU of 6oir by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 62
Descriptor: 4-fluoro-N'-(phenylsulfonyl)[1,1'-biphenyl]-3-carbohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ...
Authors:Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B.
Deposit date:2019-04-09
Release date:2019-07-03
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.
J.Med.Chem., 62, 2019
6OWI
DownloadVisualize
BU of 6owi by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor 85
Descriptor: GLYCEROL, Histone acetyltransferase KAT8, N'-[(2-fluorophenyl)sulfonyl]benzohydrazide, ...
Authors:Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B.
Deposit date:2019-05-09
Release date:2020-04-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J.Med.Chem., 63, 2020
6OIN
DownloadVisualize
BU of 6oin by Molmil
Crystal structure of MYST acetyltransferase domain in complex with inhibitor CTX-124143
Descriptor: 2-fluoro-N'-[(naphthalen-2-yl)sulfonyl]benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ...
Authors:Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B.
Deposit date:2019-04-09
Release date:2019-07-03
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.
J.Med.Chem., 62, 2019
2HGS
DownloadVisualize
BU of 2hgs by Molmil
HUMAN GLUTATHIONE SYNTHETASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUTATHIONE, MAGNESIUM ION, ...
Authors:Polekhina, G, Board, P, Rossjohn, J, Parker, M.W.
Deposit date:1999-01-04
Release date:1999-06-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis of glutathione synthetase deficiency and a rare gene permutation event.
EMBO J., 18, 1999
8DFW
DownloadVisualize
BU of 8dfw by Molmil
Crystal Structure of Human BTN2A1 in Complex With Vgamma9-Vdelta2 T Cell Receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Butyrophilin subfamily 2 member A1, ...
Authors:Fulford, T.S, Soliman, C, Castle, R.G, Rigau, M, Ruan, Z, Dolezal, O, Seneviratna, R, Brown, H.G, Hanssen, E, Hammet, A, Li, S, Redmond, S.J, Chung, A, Gorman, M.A, Parker, M.W, Patel, O, Peat, T.S, Newman, J, Behren, A, Gherardin, N.A, Godfrey, D.I, Uldrich, A.P.
Deposit date:2022-06-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Vgamma9-Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers
To Be Published
8DFY
DownloadVisualize
BU of 8dfy by Molmil
Crystal structure of Human BTN2A1 Ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Butyrophilin subfamily 2 member A1, ...
Authors:Fulford, T.S, Soliman, C, Castle, R.G, Rigau, M, Ruan, Z, Dolezal, O, Seneviratna, R, Brown, H.G, Hanssen, E, Hammet, A, Li, S, Redmond, S.J, Chung, A, Gorman, M.A, Parker, M.W, Patel, O, Peat, T.S, Newman, J, Behren, A, Gherardin, N.A, Godfrey, D.I, Uldrich, A.P.
Deposit date:2022-06-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.552 Å)
Cite:Vgamma9-Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers
To Be Published
8DFX
DownloadVisualize
BU of 8dfx by Molmil
Crystal structure of Human BTN2A1-BTN3A1 Ectodomain Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A1
Authors:Fulford, T.S, Soliman, C, Castle, R.G, Rigau, M, Ruan, Z, Dolezal, O, Seneviratna, R, Brown, H.G, Hanssen, E, Hammet, A, Li, S, Redmond, S.J, Chung, A, Gorman, M.A, Parker, M.W, Patel, O, Peat, T.S, Newman, J, Behren, A, Gherardin, N.A, Godfrey, D.I, Uldrich, A.P.
Deposit date:2022-06-22
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (5.55 Å)
Cite:Vgamma9-Vdelta2 T cells recognize butyrophilin 2A1 and 3A1 heteromers
To Be Published
5IMW
DownloadVisualize
BU of 5imw by Molmil
Trapped Toxin
Descriptor: Intermedilysin
Authors:Lawrence, S.L, Feil, S.C, Morton, C.J, Parker, M.W.
Deposit date:2016-03-07
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5IMT
DownloadVisualize
BU of 5imt by Molmil
Toxin receptor complex
Descriptor: CD59 glycoprotein, COPPER (II) ION, Intermedilysin, ...
Authors:Morton, C.J, Lawrence, S.L, Feil, S.C, Parker, M.W.
Deposit date:2016-03-06
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7001 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
5IMY
DownloadVisualize
BU of 5imy by Molmil
Trapped Toxin
Descriptor: CD59 glycoprotein, Vaginolysin
Authors:Lawrence, S.L, Morton, C.J, Parker, M.W.
Deposit date:2016-03-07
Release date:2016-08-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.
Structure, 24, 2016
2AN6
DownloadVisualize
BU of 2an6 by Molmil
Protein-peptide complex
Descriptor: Ubiquitin ligase SIAH1A, ZINC ION, peptide from Phyllopod
Authors:House, C.M, Hancock, N.C, Moller, A, Cromer, B.A, Fedorov, V, Bowtell, D.D.L, Parker, M.W, Polekhina, G.
Deposit date:2005-08-11
Release date:2006-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Elucidation of the substrate binding site of Siah ubiquitin ligase
Structure, 14, 2006

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon