4N7X
 
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3T3M
 | | A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Zhu, J, Zhu, J, Springer, T.A. | | Deposit date: | 2011-07-25 | | Release date: | 2012-03-28 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Sci Transl Med, 4, 2012
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4N7W
 | | Crystal Structure of the sodium bile acid symporter from Yersinia frederiksenii | | Descriptor: | CITRIC ACID, Transporter, sodium/bile acid symporter family, ... | | Authors: | Zhou, X, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2013-10-16 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Structural basis of the alternating-access mechanism in a bile acid transporter.
Nature, 505, 2013
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3DKV
 | | Crystal structure of adenylate kinase variant AKlse1 | | Descriptor: | 1,2-ETHANEDIOL, Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ... | | Authors: | Bannen, R.M, Bianchetti, C.M, Bingman, C.A, Bitto, E.B. | | Deposit date: | 2008-06-26 | | Release date: | 2009-06-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Crystal structure of adenylate kinase variant AKlse1.
To be Published
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2G07
 | | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, phospho-enzyme intermediate analog with Beryllium fluoride | | Descriptor: | Cytosolic 5'-nucleotidase III, MAGNESIUM ION | | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-02-11 | | Release date: | 2006-04-04 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2G06
 | | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, with bound magnesium(II) | | Descriptor: | Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID) | | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-02-11 | | Release date: | 2006-04-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2G0A
 | | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(II) bound in active site | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III, LEAD (II) ION | | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-02-11 | | Release date: | 2006-04-04 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2G09
 | | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product complex | | Descriptor: | Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-02-11 | | Release date: | 2006-04-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2G08
 | | X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product-transition complex analog with Aluminum fluoride | | Descriptor: | ALUMINUM FLUORIDE, Cytosolic 5'-nucleotidase III, MAGNESIUM ION | | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-02-11 | | Release date: | 2006-04-04 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2BDU
 | | X-Ray Structure of a Cytosolic 5'-Nucleotidase III from Mus Musculus MM.158936 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Han, B.W, Bitto, E, Bingman, C.A, Bae, E, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-10-20 | | Release date: | 2005-11-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.
J.Biol.Chem., 281, 2006
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2GU2
 | | Crystal Structure of an Aspartoacylase from Rattus norvegicus | | Descriptor: | Aspa protein, SULFATE ION, ZINC ION | | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-04-28 | | Release date: | 2006-06-20 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2Q4G
 | | Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I | | Descriptor: | CITRIC ACID, Ribonuclease inhibitor, Ribonuclease pancreatic | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.954 Å) | | Cite: | Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
J.Mol.Biol., 368, 2007
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3BVO
 | | Crystal structure of human co-chaperone protein HscB | | Descriptor: | Co-chaperone protein HscB, mitochondrial precursor, SULFATE ION, ... | | Authors: | Bitto, E, Bingman, C.A, McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2008-01-07 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of human J-type co-chaperone HscB reveals a tetracysteine metal-binding domain.
J.Biol.Chem., 283, 2008
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3DL0
 | | Crystal structure of adenylate kinase variant AKlse3 | | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Bannen, R.M, Bianchetti, C.M, Bingman, C.A, McCoy, J.G. | | Deposit date: | 2008-06-26 | | Release date: | 2009-06-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases.
Proteins, 82, 2014
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2A33
 | | X-Ray Structure of a Lysine Decarboxylase-Like Protein from Arabidopsis Thaliana Gene AT2G37210 | | Descriptor: | MAGNESIUM ION, SULFATE ION, hypothetical protein | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-06-23 | | Release date: | 2005-07-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | X-ray crystal structures of the conserved hypothetical proteins from Arabidopsis thaliana gene loci At5g11950 and AT2g37210.
Proteins, 65, 2006
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2A3Q
 | | X-Ray Structure of Protein from Mus Musculus MM.29898 | | Descriptor: | hypothetical protein | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-06-25 | | Release date: | 2005-07-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | X-Ray Structure of Protein from Mus Musculus MM.29898
To be Published
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2AB1
 | | X-Ray Structure of Gene Product from Homo Sapiens HS.95870 | | Descriptor: | hypothetical protein | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-07-14 | | Release date: | 2005-07-26 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | X-Ray Structure of Gene Product from Homo Sapiens HS.95870
To be Published
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2AMY
 | | X-Ray Structure of Human Phosphomannomutase 2 (PMM2) | | Descriptor: | 1,2-ETHANEDIOL, GLYCINE, Phosphomannomutase 2 | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-08-10 | | Release date: | 2005-08-23 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | X-Ray Structure of Human Phosphomannomutase 2 (PMM2)
To be Published
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2A13
 | | X-ray structure of protein from Arabidopsis thaliana AT1G79260 | | Descriptor: | At1g79260 | | Authors: | Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2005-06-17 | | Release date: | 2005-07-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1.
Proteins, 78, 2010
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2NYI
 | | Crystal Structure of an Unknown Protein from Galdieria sulphuraria | | Descriptor: | unknown protein | | Authors: | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2006-11-20 | | Release date: | 2006-12-12 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.
Proteins, 80, 2012
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2Q4H
 | | Ensemble refinement of the crystal structure of GALT-like protein from Arabidopsis thaliana At5g18200 | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Probable galactose-1-phosphate uridyl transferase, ... | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.834 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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2Q51
 | | Ensemble refinement of the protein crystal structure of an aspartoacylase from Homo sapiens | | Descriptor: | Aspartoacylase, PHOSPHATE ION, ZINC ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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2Q4Z
 | | Ensemble refinement of the protein crystal structure of an aspartoacylase from Rattus norvegicus | | Descriptor: | Aspartoacylase, SULFATE ION, ZINC ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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2Q4L
 | | Ensemble refinement of the crystal structure of GALT-like protein from Arabidopsis thaliana At5g18200 | | Descriptor: | Probable galactose-1-phosphate uridyl transferase, ZINC ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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2Q4S
 | | Ensemble refinement of the protein crystal structure of cysteine dioxygenase type I from Mus musculus Mm.241056 | | Descriptor: | 1,2-ETHANEDIOL, Cysteine dioxygenase type 1, NICKEL (II) ION | | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2007-05-31 | | Release date: | 2007-06-19 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
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