2Q51

Ensemble refinement of the protein crystal structure of an aspartoacylase from Homo sapiens

Summary for 2Q51

• Entry DOI: 10.2210/pdb2q51/pdb
• Related: 2GU2
• Descriptor: Aspartoacylase, ZINC ION, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: ensemble refinement, refinement methodology development, canavan disease, n-acetyl-l-aspartate, zinc-dependent hydrolase, aspartoacylase family, aminoacylase-2, acy2, aspa, structural genomics, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P45381
• Total number of polymer chains: 2
• Total formula weight: 73269.72

Authors

Levin, E.J.,Kondrashov, D.A.,Wesenberg, G.E.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2007-05-31, release date: 2007-06-19, Last modification date: 2023-11-15)

• Primary citation: Levin, E.J.,Kondrashov, D.A.,Wesenberg, G.E.,Phillips, G.N.; Ensemble refinement of protein crystal structures: validation and application.; Structure, 15:1040-1052, 2007; PubMed: 17850744; DOI: 10.1016/j.str.2007.06.019

Experimental method

X-RAY DIFFRACTION (2.8 Å)