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2XVI
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BU of 2xvi by Molmil
Crystal structure of the mutant bacterial flavin containing monooxygenase (Y207S)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN-CONTAINING MONOOXYGENASE, ...
Authors:Cho, H.J, Kang, B.S.
Deposit date:2010-10-26
Release date:2011-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural and Functional Analysis of Bacterial Flavin-Containing Monooxygenase Reveals its Ping-Pong-Type Reaction Mechanism.
J.Struct.Biol., 175, 2011
4R3Z
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BU of 4r3z by Molmil
Crystal structure of human ArgRS-GlnRS-AIMP1 complex
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ...
Authors:Fu, Y, Kim, Y, Cho, Y.
Deposit date:2014-08-18
Release date:2014-10-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.033 Å)
Cite:Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation
Proc.Natl.Acad.Sci.USA, 111, 2014
6JPV
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BU of 6jpv by Molmil
Structural analysis of AIMP2-DX2 and HSP70 interaction
Descriptor: Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Authors:Cho, H.Y, Son, S.Y, Jeon, Y.H.
Deposit date:2019-03-28
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15000653 Å)
Cite:Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Nat.Chem.Biol., 16, 2020
6K39
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BU of 6k39 by Molmil
Structural analysis of AIMP2-DX2 and HSP70 interaction
Descriptor: Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Authors:Cho, H.Y, Son, S.Y, Jeon, Y.H.
Deposit date:2019-05-16
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3981427 Å)
Cite:Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Nat.Chem.Biol., 16, 2020
5HWT
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BU of 5hwt by Molmil
Crystal structure of apo-PAS1
Descriptor: Sensor histidine kinase TodS
Authors:Hwang, J, Koh, S.
Deposit date:2016-01-29
Release date:2016-03-02
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
2QMQ
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BU of 2qmq by Molmil
Crystal structure of a n-myc downstream regulated 2 protein (ndrg2, syld, ndr2, ai182517, au040374) from mus musculus at 1.70 A resolution
Descriptor: BENZOIC ACID, MAGNESIUM ION, NONAETHYLENE GLYCOL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2007-07-16
Release date:2007-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.
J.Biol.Chem., 286, 2011
2JDJ
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BU of 2jdj by Molmil
crystal structure of HapK from Hahella chejuensis
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, REDY-LIKE PROTEIN, ...
Authors:Kang, B.S, Cho, H.J, Kim, K.J.
Deposit date:2007-01-10
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight of the Role of the Hahella Chejuensis Hapk Protein in Prodigiosin Biosynthesis.
Proteins, 70, 2008
2V66
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BU of 2v66 by Molmil
Crystal Structure of the coiled-coil domain of Ndel1 (a.a. 58 to 169) C
Descriptor: MERCURY (II) ION, NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1
Authors:Tarricone, C, Perrina, F, Musacchio, A.
Deposit date:2007-07-13
Release date:2007-11-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly.
Structure, 15, 2007
4ALU
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BU of 4alu by Molmil
Benzofuropyrimidinone Inhibitors of Pim-1
Descriptor: 8-bromo-2-(2-chlorophenyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1
Authors:Stout, T.J, Adams, L.
Deposit date:2012-03-05
Release date:2013-01-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ALW
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BU of 4alw by Molmil
Benzofuropyrimidinone Inhibitors of Pim-1
Descriptor: 8-BROMANYL-2-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE, IMIDAZOLE, PIM-1 KINASE
Authors:Stout, T.J, Adams, L.
Deposit date:2012-03-05
Release date:2013-01-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ALV
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BU of 4alv by Molmil
Benzofuropyrimidinone Inhibitors of Pim-1
Descriptor: 8-bromo-2-{2-chloro-4-[(piperidin-4-ylmethyl)amino]phenyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1
Authors:Stout, T.J, Adams, L.
Deposit date:2012-03-05
Release date:2013-01-16
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4ANM
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BU of 4anm by Molmil
Complex of CK2 with a CDC7 inhibitor
Descriptor: 8-BROMANYL-2-[[(3S)-3-OXIDANYLPYRROLIDIN-1-YL]METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE, CASEIN KINASE II SUBUNIT ALPHA
Authors:Stout, T.J.
Deposit date:2012-03-20
Release date:2012-05-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Xl413, a Potent and Selective Cdc7 Inhibitor.
Bioorg.Med.Chem.Lett., 22, 2012
5DQY
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BU of 5dqy by Molmil
A fully oxidized human thioredoxin
Descriptor: BENZOIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Hwang, J.
Deposit date:2015-09-15
Release date:2015-12-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of fully oxidized human thioredoxin.
Biochem.Biophys.Res.Commun., 467, 2015
1RJA
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BU of 1rja by Molmil
Solution Structure and Backbone Dynamics of the Nonreceptor Tyrosine Kinase PTK6/Brk SH2 Domain
Descriptor: Tyrosine-protein kinase 6
Authors:Hong, E, Shin, J, Lee, W.
Deposit date:2003-11-18
Release date:2004-07-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the Non-receptor Protein-tyrosine Kinase-6 Src Homology 2 Domain
J.Biol.Chem., 279, 2004
2Y79
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BU of 2y79 by Molmil
STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS
Descriptor: CALCIUM ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Cho, H.Y, Cho, H.J, Kang, B.S.
Deposit date:2011-01-30
Release date:2011-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett., 585, 2011
2Y8H
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BU of 2y8h by Molmil
STRUCTURE OF THE FIRST GAF DOMAIN E87G MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS
Descriptor: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, TWO COMPONENT SENSOR HISTIDINE KINASE DEVS
Authors:Cho, H.Y, Cho, H.J, Kang, B.S.
Deposit date:2011-02-07
Release date:2011-02-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett., 585, 2011
5ZNX
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BU of 5znx by Molmil
Crystal structure of CM14-treated HlyU from Vibrio vulnificus
Descriptor: Transcriptional activator
Authors:Park, N, Kim, S, Jo, I, Ahn, J, Hong, S, Jeong, S, Baek, Y.
Deposit date:2018-04-11
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species.
Sci Rep, 9, 2019
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